... Open Access The diagnostic value of serum leptin monitoring and its correlation with tumor necrosis factor -a in critically ill patients: a prospective observational studyAyman Abd Al-Maksoud Yousef1*, ... necrosis factor -a (TNF -a) as an importantcytokine in inflammatory states including sepsis [7]. Leptin is an adipocyte secreted hormone. In additionto playing a role in energy regulation, leptin also ... calcium, aspartate aminotransferase,alanine aminotransferase, prothrombin time, albumin,CRP, leptin, IL-6 and TNF -a) and arterial blood gasanalysis. Routine cultures of blood, urine and suspectedsites...