Báo cáo y học: "Interactions between human immunodeficiency virus (HIV)-1 Vpr expression and innate immunity influence neurovirulence " doc

... Interactions between human immunodeficiency virus (HIV)-1 Vpr expression and innate immunity influence neurovirulence. Retrovirology 2011 8:44. Submit your next manuscript to BioMed Central and take ... 27:3703-3711. 21. Kitayama H, Miura Y, Ando Y, Hoshino S, Ishiz aka Y, Koyanagi Y: Human immunodeficiency virus type 1 Vpr inhibits axonal outgrowth thro...

Ngày tải lên: 13/08/2014, 01:20

... Access Inhibition of human immunodeficiency virus type-1 by cdk inhibitors Irene Guendel 1,3† , Emmanuel T Agbottah 2† , Kylene Kehn-Hall 3 , Fatah Kashanchi 1,3,4* Abstract Current therapy for human immunodeficiency ... Guendel et al.: Inhibition of human immunodeficiency virus type-1 by cdk inhibitors. AIDS Research and Therapy 2010 7:7. Submit your next manuscript to BioM...

Ngày tải lên: 10/08/2014, 05:21

... protease autoprocessing. Background Human immunodeficiency virus 1 (HIV-1) is the causa- tive pathogen of AIDS. The HIV protease is a virus- encoded enzyme absolutely required for virus propa ga- tion and infectivity. In ... HG: Cleavage of human immunodeficiency virus type 1 proteinase from the N-terminally adjacent p6* protein is essential for efficient Gag polyprotein pro...

Ngày tải lên: 10/08/2014, 05:21

... protease and inhibition of assembly and budding of virus- like particles. Virology 1993, 193:661-671. 7. Park J, Morrow CD: Overexpression of the gag-pol precursor from human immunodeficiency virus type ... USA 1996, 93:4137-4141. 26. Yu SF, Baldwin DN, Gwynn SR, Yendapalli S, Linial ML: Human foamy virus replication: a pathway distinct from that of retroviruses and hepadnavi...

Ngày tải lên: 13/08/2014, 01:21

... min by measuring pixel inten- sity of the highest band at each time point relative to fully phosphorylated wild-type PAG (Fig. 4B). The wild-type PAG protein was rapidly phosphorylated by Fyn, ... 1C), flanked by strands b4 and b5. The variable loops n-Src and RT are principal determinants for ligand recognition, orientation, and specificity of this domain, with residues Tyr91 and Tyr13...

Ngày tải lên: 24/03/2014, 00:21

... Sawada 1 , Yuta Kochi 2 and Kazuhiko Yamamoto 1 1 Department of Allergy and Rheumatology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan 2 Laboratory ... detect the IL-32 expression in the synovial lining layers, where monocytes and synovial fibroblasts usually exist. Synovial fibroblasts pro- duce cytokines and proteases, which play...

Ngày tải lên: 09/08/2014, 08:23

... hampered by pheno- copy, incomplete penetrance, and genetic heterogeneity [9]. The complexity of the genetics of asthma and other atopy-associated phenotypes is reflected by an increas- ingly large ... in lifestyle significantly contribute to disease expression, heri- tability has been shown to play a major role in the patho- genesis of allergic disease. Multiple twin and family analys...

Ngày tải lên: 12/08/2014, 18:20

... lymphocytes and CD3 in resting lymphocytes. In activated T lymphocytes, LFA-1, CD28 and CD69 expression was 16.6 ± 0.7, 18.9 ± 1.9 and 6.6 ± 1.3, respectively, and was significantly reduced by fibroblasts ... lung fibroblasts and T-lym- phocytes mutually interact. Activated lymphocytes induce COX-2 mRNA accumulation and protein expression and dramatically increase both trans...

Ngày tải lên: 12/08/2014, 18:22

Ngày tải lên: 12/08/2014, 19:22

... HE: Cytoplasmic assembly and accumulation of human immunodeficiency virus types 1 and 2 in recombinant human colony-stimulat- ing factor-1-treated human monocytes: an ultrastructural study. J ... cells. To generate the expression plasmid for the Myc .Vpr protein (pEF.Myc .Vpr) , the vpr gene from HIV-1 NL4-3 was inserted into pEF.BOS.Myc. For the expression of the hybrid...

Ngày tải lên: 13/08/2014, 09:20