Báo cáo y học: "CD4+ T cells spontaneously producing human immunodeficiency virus type I in breast milk from women with or without antiretroviral drugs" potx

... 53:135-148. doi:10.1186/1742-4690-8-34 Cite this article as: Valea et al .: CD4 + T cells spontaneously producing human immunodeficiency virus type I in breast milk from women with or without antiretroviral drugs. Retrovirology 2011 ... cells indicated that the virus particles secreted into the cell culture supernatants from breast milk cells ar...

Ngày tải lên: 13/08/2014, 01:20

... charges in their V3 loop become more resistant to the anti-V3 neutralizing antibodies [21]. This selective force is continuously enriching the R5 viruses during long-lasting persistent infection. The ... viruses. In conclusion, this study, for the first time, characterizes the genotypic and phenotypic properties of HIV-1 CRF07_BC strains circulating in Xinjiang province of China, in c...

Ngày tải lên: 12/08/2014, 23:21

... viral proteins that can bind p53 might inhibit its pro-apoptotic activity, allowing more cells to become either productively or latently infected with HIV-1 [52]. It can be postulated that the ... mRNA in response to virus infection. This process is aimed at preventing the spread of infection by allowing a more rapid induction of apoptosis. It is impor- tant to note that an increase...

Ngày tải lên: 13/08/2014, 05:21

... unique transcriptional milieu in this evolutionarily conserved target cell of all lentiviruses. Importantly, transient trans- complementation by ex vivo nucleofection with the Tat-interacting protein Cyclin ... importantly, while integrants were readily amplified by the newly developed PCR strat- egy at this late time point in Rat2 cells infected with the IN wt vector, provirus fo...

Ngày tải lên: 13/08/2014, 05:22

... healthy individuals, where they retain their capacity to initiate autoimmune inflammation [2], negative selection in the thymus is not sufficient to prevent the activation of self-reactive T cells ... of CD4 + CD25 high T cells from patients with active RA with regard to their ability to suppress pro-inflammatory cytokine production that reverts after treatment with TNF-neut...

Ngày tải lên: 09/08/2014, 06:22

... positively corre- lated with disease activity, and the suppressive function of these cells was intact in cultures without antigen-presenting cells. The functional activity of both patient and healthy control ... Foxp3 + CD4 + cells and correlations with disease activity in SLE may be explained by a variability of disease activity in the patients studied. Investigators who rep...

Ngày tải lên: 09/08/2014, 13:22

... characterized by dominant inhibitory activities, can interfere with lentiviral replication in a species-spe- cific manner. Of potential relevance in the rodent context, the incorporation of the cytidine ... NIH 3T3 fibroblasts infected with either the integration-competent (IN wt) HIV-CMV-GFP or an integration-defective iso- genic HIV-1 vector (IN( D64V)), the latter carrying a c...

Ngày tải lên: 13/08/2014, 05:21

... [38]. Accordingly, it is possible that the mechanism of membrane interaction and destabilization is different in the case of Ab, but it is fair to say that the similarity with the fusion domain of a virus ... data were multi- plied by shifted sine functions (COSY) or lorentz-to-gauss windows (NOESY, TOCSY) in the direct dimension, and by shifted sine or sine square functions in...

Ngày tải lên: 08/03/2014, 09:20

... period. Results from this study suggest that patients requiring a switch in antipsychotic medication can benef it from switching to aripiprazole treatment in both the short and long term. In this study, ... abnormalities while receiving treatment with other antipsychotic agents may benefit from switching to aripiprazole. Hyperprolactinemia, which is associated with some antips...

Ngày tải lên: 09/08/2014, 01:21

... Sahlgrenska University Hospital or at Karolinska University Hospital. The patients were consecutively incorporated into the study. The patients underwent a thorough clinical examination by an experienced ... showed that SLE patients with MRI findings compared with those without MRI findings had significantly higher CSF-tau levels. These increases reflect the neuronal damage of the bra...

Ngày tải lên: 09/08/2014, 01:23