Báo cáo y học: "Selected amino acid mutations in HIV-1 B subtype gp41 are Associated with Specific gp120V3 signatures in the regulation of CoReceptor usag" pot
Báo cáo y học: "Selected amino acid mutations in HIV-1 B subtype gp41 are Associated with Specific gp120V3 signatures in the regulation of CoReceptor usag" pot
... extracellular domain of gp41 is consistent with the idea that gp41 may act as a scaffold in < /b> order to maintain the stability of the gp120 /gp41 complex, and therefore finally influencing the viral tropism ... likely that the principal driving force in < /b> the evolution of the V3 region of HIV-1 < /b> is the cell receptor usage, the escape from host i...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: "Single amino acid change in gp41 region of HIV-1 alters bystander apoptosis and CD4 decline in humanized mice" potx
... also maintained at the 8 weeks end point of our study when we looked at the CD4 levels in < /b> the spleen (Figure 2B) . In < /b> a repeat of the study in < /b> a larger set of mice consisting of 6 mice per group the ... were both compromised in < /b> the V38E mutant. These studies are indicative that the pathogenesis of HIV maybe partially related to the fuso...
Ngày tải lên: 11/08/2014, 21:21
Báo cáo y học: " γδ T lymphocytes from cystic fibrosis patients and healthy donors are high TNF-α and IFN-γ-producers in response to Pseudomonas aeruginosa" pptx
... contrast Th2-type cytokines, as IL-4, induce antibody production by B lymphocytes [22]. Production of Th1 cytokines by CD4-positive lymphocytes has been suggested to be impaired in < /b> CF [17,23]. γδ T cells are ... support the hypothesis that γδ T lymphocytes play an important role in < /b> the immune response to PA and in < /b> the chronic inflammatory lung reaction in < /...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: " Off hour admission to an intensivist-led ICU is not associated with increased mortality" pps
... time period in < /b> which intensivists are rou- tinely present in < /b> the unit and off hours was defined by the time period in < /b> which intensivists are not routinely present in < /b> the ICU but available for consultation ... done in < /b> the present study, that the first few hours of intensive care are more decisive than the time that follows, a difference...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects"
... Considering that no pre- vious report exist reporting on the use of EHA com- bined with autologous bone but without the applica- tion of a membrane in < /b> the treatment of infra bone de- fects, our clinical ... 2005 12. Turley EA. The role of cell -associated hyaluronan bindig pro- tein in < /b> fibroblast behaviour. In:< /b> Evered D, Whelan J, editors. The Biology...
Ngày tải lên: 03/11/2012, 11:35
Tài liệu Báo cáo Y học: BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro Implications in the BIGH3-linked corneal dystrophies pptx
... formation of amyloid fibrils, suggesting the importance of the hydropho- bic NH 2 -end of the peptides. In < /b> the same way, removing the CONH 2 -terminus of the peptides resulted in < /b> increased amyloid fibril ... significantly reduced in < /b> the mix containing BB1 (LPVVD) (35% when compared with the control curve of C110)131 in < /b> the absence of BB...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo Y học: Introducing Wilson disease mutations into the zinc-transporting P-type ATPase ofEscherichia coli The mutation P634L in theÔhingeÕ motif (GDGXNDXP) perturbs the formation of the E2P state pdf
... contribute to the binding site of two calcium ions inside the lipid bilayer. The P domain, in < /b> which the phosphorylated aspartate resides, is composed of the N- and C-terminal parts of the longer cytoplasmic ... wild-type. The amounts of the P 401L and P476L ATPases are about 60% of the wild- type level. In < /b> assays described below, the same amount...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: Mitochondrial DNA deletion mutations A causal role in sarcopenia docx
... represented by the black bars using the left axis, fiber number is represented by the white bars using the right axis, muscle cross-sectional area is represented by the width of the black bars using the ... until they are no longer observable by light microscopy, suggesting that they are broken. The fiber can often be found again several sections later. Our analysis of...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo khoa học: Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (AriceptÒ) to cholinesterases doc
... predicted by these studies. The mutation of Tyr337 to Phe or Ala in < /b> Mo AChE resulted in < /b> a gain of binding energy suggesting that the bulky Tyr residue was sterically hindering the binding of E2020 ... K ss represents the binding of a second substrate molecule to the binary enzyme-substrate com- plexes and b reflects the efficiency of hydrolysis of the t...
Ngày tải lên: 30/03/2014, 20:20
Báo cáo y học: "Dietary fatty acid intake affects the risk of developing bone marrow lesions in healthy middle-aged adults without clinical knee osteoarthritis: a prospective cohort study" docx
... However, there are no longitudinal stud- ies examining the role of fatty acids on incident BMLs in < /b> either healthy or OA populations. Therefore, the aim of this study was to examine the association between ... BMLs. Conclusions Increased fatty acid < /b> consumption may increase the risk of developing BMLs. As subchondral bone is important in < /b> maintaining joint i...
Ngày tải lên: 09/08/2014, 14:20