Báo cáo y học: "The evolution of HIV-1 reverse transcriptase in route to acquisition of Q151M multi-drug resistance is complex and involves mutations in multiple domains" ppt

... evolution of HIV-1 reverse transcriptase in route to acquisition of Q151M multi-drug resistance is complex and involves mutations in multiple domains Jean L Mbisa 1* , Ravi K Gupta 2 , Desire Kabamba 3 , ... reduced susceptibility to all nucleoside reverse transcriptase inhibitors (NRTIs) excluding tenofovir (TDF). This pathway emerges after long...

Ngày tải lên: 13/08/2014, 01:20

... 2002 introns in the evolutionary pathway to c-type genes, but rather the acquisition of an interdomain intron in the evolution of c-crystallins, and of both interdomain and intermotif introns in the evolution ... in favour of a late insertion of introns in crystallin-type genes, as opposed to a late deletion of pre-existing introns, may be based on the intr...

Ngày tải lên: 24/03/2014, 04:21

... out- come of a depressive episode, namely the patient’s psychia- tric and medical history, the p resence of somatic symptoms, including painful symp toms, and demographic and social variables, need to ... adopted to evaluate depressive symptoms, while somatic and painful physical symptoms were assessed by using the 28-item Somatic Symptom Inventory (SSI-28) and a VAS. Result...

Ngày tải lên: 09/08/2014, 01:21

... arthritis. It remains to be determined whether circulating IL-1F8 can contribute to joint inflammation in rheumatoid arthritis. Introduction Until recently, the IL-1 family of cytokines included four ... Internal Medicine, University Hospital and Department of Pathology and Immunology, University of Geneva School of Medicine, Geneva, Switzerland 2 Division of Genomic Medi...

Ngày tải lên: 09/08/2014, 08:22

... not this is related to limited capacity for remodelling of the myocardium, to abnormal coron- ary arterial anatomy, to limited coronary arterial adapta- tion capacity or to other factors is yet ... 32.0 years). Coronary anatomy In 13 out of the 32 patients information on coronary anatomy was explicitly available. In one patient a cir- cumflex coronary artery arose from the...

Ngày tải lên: 10/08/2014, 09:22

... Germany. 17 Vitos Hospital of Psychiatry and Psychotherapy Merxhausen, Hofgeismar, Germany. 18 Vitos Haina Forensic Psychiatric Hospital, Haina, Germany. 19 Department of Psychiatry and Psychotherapy, Regional ... Hospital of Forensic Psychiatry Eltville, Eltville, Germany. 10 Vitos Hospital of Psychiatry and Psychotherapy Merxhausen, Kassel, Germany. 11 Department of Psychiat...

Ngày tải lên: 11/08/2014, 16:22

... suggestive of constrictive physiology. Since the patient continued to remain asymp- High power histologic examination showing the epicardium with lymphoplasmocytic infiltration (hematoxylin-eosin stain)Figure ... instrumental in determining the diagnosis of epicarditis. Prior case reports have suggested the etiology of epicardi- tis to be infectious in origin, including reports...

Ngày tải lên: 11/08/2014, 19:21

... protocol, to the data acquisition, and to data analysis. LM initiated the study within the Phythea laboratories, discussed the protocol, provided the financing for the study, and contrib- uted to ... data mon- itoring; LM is Medical Director, Phythea Laboratories; NM is Professor of Clinical Pharmacology, Head of the Department of Pharmacology, and coordinator of the...

Ngày tải lên: 12/08/2014, 11:22

... oscillating piston pump akin to the woofer of a loudspeaker vibrates this pressurized, flowing gas at a frequency that is generally set between 3 and 10 Hz. A portion of this flow is thereby pumped into ... Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada 2 Associate Professor, Division of Respirology and Interdepartment...

Ngày tải lên: 12/08/2014, 19:22

... Irgb9 and Irgb10, carry the amino-terminal myristoylation signal MGxxxS [18]. This sequence in Irga6 (IIGP1) is indeed myristoylated in vitro [19] and in vivo, and, as expected, favors binding of ... TIQERLSRYIQEFCLANGYLLP KNSFLKEIFYLKYYFL SLEDKLFKYIKHISSVTGGPV AAVTYYRMAYYLQNLFL SIIAQATSAAEAFCAVKGGPE SSAFQALKVYYRRTQFL SLGEKLLRYVEKFCSVSGGLI ATGVYFRKIFYLQNYFL PLGEKLLKYVEKFCSV...

Ngày tải lên: 14/08/2014, 15:20