Báo cáo y học: "HIV-1 integrase modulates the interaction of the HIV-1 cellular cofactor LEDGF/p75 with chromati" pptx
Báo cáo Y học: Cloning, chromosomal localization and characterization of the murine mucin gene orthologous to human MUC4 pdf
... sequence of the 3¢ part of the gene encompassing 17 kb. Three poly(A) signals were found after the stop codon. Analysis of the four cosmid clones by PCR revealed that they do not contain any sequence ... Contigs analysis of the Human Genome Project did not reveal any other mucin on chromosome 3q29 and, interestingly, our analysis allowed the determination of the genomi...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1 pot
... interaction of the N-ter- minus of MDM2 with the N-terminus of p53, and an interaction of the acid domain of MDM2 with the central domain of p53 [24]. Accordingly, ligands such as the NUTLIN and BOX1 peptides ... begin to analyse the role of the ATP- binding domain as a modifier of transcription factors in vivo, with the prospect of developing drugs...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo Y học: Novel regulatory regions found downstream of the rat B29/Ig-b gene docx
... the footprinted region had activity similar to that of the control. The sequence responsible for the major mobility shift and the transc riptional enhancing activity in the 0 .3-kb DNA with the ... sequence. By footprint a nalysis, 20 bases in the middle of the 0.3-kb DNA were protected by Y3 nuclear extract in which the consensus binding site for the OCT family w...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: "Validation and test-retest reliability of the Royal Free Interview for Spiritual and Religious Beliefs when adapted to a Greek population" doc
... Potential subjects were recruited from the community on the basis of their availability. They received a brief explanation of the purpose and the aim of the study, and those who agreed to participate ... experience, they answered that the incident was a prophetic dream, the recovery from an accident or an illness, the presence of an invisible force, the birth of th...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: " Ageing, autoimmunity and arthritis: Senescence of the B cell compartment — implications for humoral immunity" pptx
... quality of the humoral response of aged individuals. Study of the GC reaction in healthy aged humans is impractical for obvious reasons. Nonetheless, the products of the GC reaction, namely antibodies, ... anti-sheep erythrocyte antibody secreting cells than do their young counterparts (probably from follicular B cells), but they produce significant levels of antibody reacti...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Discriminant validity, responsiveness and reliability of the rheumatoid arthritis-specific Work Productivity Survey (WPS-RA)" potx
... weeks 0, 1, 2, and 4 and then q4w until the end of the study or withdrawal; the SF- 36 was administered at weeks 0, 4, and 12 and at the end of the study or withdrawal; and the WPS-RA was administered at ... people with RA drop out of the workforce due to their disability, and yet they still need to do work around the house or someone has to do it for them; therefore,...
Ngày tải lên: 09/08/2014, 14:21
Báo cáo y học: "Comprehensibility, reliability, validity, and responsiveness of the Thai version of the Health Assessment Questionnaire in Thai patients with rheumatoid arthritis" potx
... reliability of the Thai HAQ has been shown to be acceptable with the ICC of 0.89. The test-retest reliability of the Thai HAQ was less than those of the Korean and Japa- nese HAQs but was higher than the ... 0.75. The SRMs for the Thai HAQ com- pared with the other measures of RA disease activity are shown in Table 5. Discussion Approximately 90% of the pat...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Archaeal phylogeny based on proteins of the transcription and translation machineries: tackling the Methanopyrus kandleri paradox" pdf
... triggered the initial evolutionary acceleration of RNA polymerase sub- units that may have facilitated the loss of TFS. Nevertheless, the hypothesis of a direct effect of the loss of a TFIIS-like ... displays an activity more consistent with the function of eukaryotic TFIIS [43,44]. Eukaryotic TFIIS has the ability to strongly enhance the weak intrinsic nuclease ac...
Ngày tải lên: 09/08/2014, 20:21
Báo cáo y học: " Comparative transcriptomics among floral organs of the basal eudicot Eschscholzia californica as reference for floral evolutionary developmental studies" pps
... replicates of each tissue. The points of the arrows point to the samples labeled with Cy5 dyes while the bases of the arrows point to the samples labeled with Cy3 dyes. Zahn et al. Genome Biology 2010, ... families. (a) The AGO gene family; (b) The PAZ gene family; (c) The MYB gene family; (d) The ZHD gene family; (e) The ARF gene family; (f) The bZIP gene fa...
Ngày tải lên: 09/08/2014, 22:23
Báo cáo y học: "Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureu" pot
... and methods). With the exception of the partial block of the cytochrome isoenzymes at high con- centrations of IQ-143, there was no other block pre- dicted for any of the other pathways modeled. ... control with no antibiotic added. In vitro inhibitory activity of IQ-143 on CYP enzymes To test the inhibito ry activity of IQ-143 on the six main human drug-metabo liz...
Ngày tải lên: 09/08/2014, 22:24