Báo cáo y học: "trong mucosal immune responses in SIV infected macaques contribute to viral control and preserved CD4+ T-cell levels in blood and mucosal tissues" pps
Báo cáo y học: "trong mucosal immune responses in SIV infected macaques contribute to viral control and preserved CD4+ T-cell levels in blood and mucosal tissues" pps
... determined in blood and all mucosal sites by quantifying viral RNA and proviral DNA load. Results Baseline characteristics of SIV infected RM This study included 30 SIV- infected rhesus monkeys of Indian ... Schultheiss et al.: Strong mucosal immune responses in SIV infected macaques contribute to viral control and preserved CD4 + T-cell levels...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: " CXCR2 is critical for dsRNA-induced lung injury: relevance to viral lung infection" pps
... recruitment com- pared to controls (Fig. 2B and 2C). DsRNA induces increased lung injury To determine if the influx of neutrophils into lung airways and parenchyma results in lung injury, we measured ... Respiratory viral infections are characterized by the infiltration of leukocytes, including activated neutrophils into the lung that can lead to sustained lung injury and pote...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: "Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy" pps
... the loss of CD4+ T cells in HIV-1 infected patients. Infected CD4+ T cells initially undergo cell cycle arrest at G2 caused by a viral accessory protein, Vpr, and eventually cytolysis [1,2]. ... PI3K/Akt inhibitors, including clinically available Miltefosine, dramatically reduced HIV-1 production from long-living virus -infected macrophages. These PI3K/ Akt inhibitors hyper-sen...
Ngày tải lên: 13/08/2014, 06:20
Báo cáo y học: " The pp24 phosphoprotein of Mason-Pfizer monkey virus contributes to viral genome packaging" potx
... innate ability to assemble into immature capsids or procapsids in the cytoplasm, recog- nize and package the viral RNAs and glycoproteins and facilitate budding from the plasma membrane. During viral ... packages significantly less vRNA into particles lead us to hypothesize that correct Glycoprotein incorporation and Gag processingFigure 4 Glycoprotein incorporation and G...
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: "Pharmacological disruption of insulin-like growth factor 1 binding to IGF-binding proteins restores anabolic responses in human osteoarthritic chondrocytes" ppt
... Holly JMP: Changes in the local regulation of insulin-like growth factors I and II and insulin-like growth factor-binding proteins in osteoarthritis of the canine stifle joint secondary to cruciate ... of insulin-like growth factor-bind- ing protein ligand inhibitors in vitro and in vivo. J Cereb Blood Flow Metab 2003, 23:1160-1167. 45. Lowman HB, Chen YM, Skelton NJ, Morten...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Regulating the immune system: the induction of regulatory T cells in the periphery Jane H Buckner1 and Steven F Ziegler2" pot
... J, Yamazaki S, Sakihama T, Itoh M, Kuniyasu Y, Nomura T, Toda M, Takahashi T: Immunologic tolerance maintained by CD25 + CD4 + regulatory T cells: their common role in controlling autoimmunity, ... [43,44], and the removal of CD4 + CD25 + using depleting antibody leads to a similar autoimmune phenotype seen in mice after thymectomy [45]. Studies of experimental autoimmune encephalo-...
Ngày tải lên: 09/08/2014, 01:24
Báo cáo y học: " The intracellular detection of MIP-1beta enhances the capacity to detect IFN-gamma mediated HIV-1-specific CD8 T-cell responses in a flow cytometric setting pro" ppsx
... other hand, the introduction of polychromatic flow- cytometry-based assays such as the intracellular cytokine staining (ICS) strongly improved the capacity to detect several markers on a single ... be applied to any staining combination including IFN-γ and MIP-1β in combination with the appropriate lineage markers. Thus, for investigators with no access to sophisticated flow cytomet...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Early innate immune events induced by prolonged cold ischemia exacerbate allograft vasculopathy" potx
... neutrophil influx Given their role in immediate innate inflammato ry responses and tissue damage, and our previous evidence implicating N∅ as effectors in early AV events, we examined early N∅ influx in both CI groups. ... we chose were designed to mimic the clinical situation, with 20 min in cold saline being the standard cold ischemic time in our laboratory and 60 min i...
Ngày tải lên: 10/08/2014, 09:23
Báo cáo y học: "Assessment of immune response to repeat stimulation with BCG vaccine using in vitro PBMC model" pdf
... Dickinson Biosciences) and incubated for 30 minutes at room tem- perature. The cells were again washed and resuspended in 1 ml saline and subjected to flowcytometry. Cells col- lected using flow cytometry on a ... listeriolysin, which improves the capacity to stimulate antimycobacterial T-cell responses [11,12]. An interesting complementary approach to improving BCG immunoge...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: "Levamizole enhances immune responsiveness to intra-dermal and intra-muscular hepatitis B vaccination in chronic hemodialysis patients" pps
... of vaccination which could be more effective than the conventional intramuscular (IM) rout. It is effective in inducing HBs antibody production by increasing T and B lymphocyte responsiveness, ... B immunity in hemodialysis patients. vaccine 2002, 20:3230-35. 21. Pyone kyi K, May Oo K, Moh Htun M, Win Maw T, Khin Khin A, San San O, et al.: Clinical trial of the intradermal administratio...
Ngày tải lên: 11/08/2014, 10:23