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Báo cáo y học: "Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembl" potx

Báo cáo y học:

Báo cáo y học: "Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembl" potx

... AccessHighly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assemblyJörg Votteler1†, Liane Neumann1†, Sabine Hahn1, Friedrich Hahn1, Pia Rauch1, Kerstin ... HIVinfection of human lymphoid tissue: correlation of CD4+T cell depletion and virus syncytium-inducing/non-syncytium-inducing phenotype in histocultures inoculated with laboratory strains and patient ... processing by introducing specific mutationsinto the CA-SP1 cleavage site can rescue the defects in core assembly and infectivity induced by the S40F muta-tion. It is known that the affinity of...
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Báo cáo y học: " Central role of nitric oxide in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus" potx

... NG-mono-methyl-L-arginine and nitronidazole both inhibited its production, suggesting a role for NO in regulating IFN-γ synthesis [17]. NO preferentially promotes IFN-γ syn the-sis and type  ... increased NO production of lupus monocytes [31].NO regulates mammalian target of rapamycin activity and TCRζ expression in SLE e mammalian target of rapamycin (mTOR) is a serine/ threonine ... other proinfl ammatory cytokines such as IL-21 and IL-22. Increased levels of IL-17 have been observed in patients with RA. Indeed, IL-17 can directly and indirectly promote cartilage and bone...
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Báo cáo khoa học: The role of residue Thr249 in modulating the catalytic efficiency and substrate specificity of catechol-2,3-dioxygenase from Pseudomonas stutzeri OX1 ppt

Báo cáo khoa học: The role of residue Thr249 in modulating the catalytic efficiency and substrate specificity of catechol-2,3-dioxygenase from Pseudomonas stutzeri OX1 ppt

... micro-organism, since the NADH consumed by the mono-oxygenase-catalyzed hydroxylations of m-xylene and p-xylene cannot be restored by the lower pathway reac-tions. This inefficiency results in a loss ... monoanionic binding of 2,3-dihydroxybi-phenyl to 2,3-dihydroxybiphenyl 1,2-dioxygenase fromUV resonance Raman spectroscopy, UV ⁄ Vis absorptionspectroscopy, and crystallography. J Am Chem ... (1987) Purification and properties of 2,3-dihydroxybiphenyl dioxygenasefrom polychlorinated biphenyl-degrading Pseudomonaspseudoalcaligenes and Pseudomonas aeruginosacarrying the cloned bphC...
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Báo cáo y học: "A psychophysiological investigation of laterality in human emotion elicited by pleasant and unpleasant film clips" pptx

... wasevidence of excessive activity (including a prematureeyeblink) during the baseline period. They were alsorejected if there was no evidence of an eyeblink havingbeen evoked by the startle probe. Altogether, ... baseline EMG and latency to response onset, only the findings onaffective ratings and startle amplitude are reported here.Although no significant interaction effect appeared in the above analysis, ... obtained here and those observed by others [9,10,24] in showing later-alisation of the effects of startle probes. In order toexamine this possibility, in additional analyses every sin-gle startle...
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Báo cáo y học: "Altered expression of inflammatory cytokines in primary osteoarthritis by human T lymphotropic virus type I retrovirus infection: a cross-sectional study" pps

... changes in HAAP include marked proliferation of synoviocytes in thesynovial lining layer, gross infiltration of lymphocytes, and migration of atypical lymphocytes with nuclear indentationinto ... osteophytes and definite joint space narrowing. bScoring was as follows: +/-, minimum staining in one area of the tissue; +, patchy staining involving several areas; ++, moderate diffuse staining. ... taking a variety of medications, including non-steroi-dal anti-inflammatory drugs, external splints and intra-artic-ular injections of prednisone and/ or hyaluronic acid.Intra-articular injection...
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Báo cáo y học: "Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination" pot

... (CIA) and experimental autoimmune encephalomyelitis (EAE) using myelin and synovial antigen arrays. (a, b) Synovial and (d, e) myelin arrays were produced by printing synovial and myelin peptides ... MBP, myelin oli-godendrocyte glycoprotein (MOG), myelin-associatedglycoprotein, myelin-associated oligodendrocyte basic protein and αB-crystallin.Epitope spreading of autoantibody responses in ... protein 20, phosphatidyleth-anolamine binding protein 1, tyrosine 1-monoxygenase activat-ing protein gamma, malate dehydrogenase 2, glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase...
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Báo cáo y học: " Role of dopamine D2 receptors in ischemia/ reperfusion induced apoptosis of cultured neonatal rat cardiomyocytes" potx

... HZ, Tian Y, Lv YJ,Yang BF, Xu CQ: Involvement of calcium-sensing receptor in cardiachypertrophy-induced by angiotensinII through calcineurin pathway in cultured neonatal rat cardiomyocytes. Biochem ... ratventricular myocytes induced by ischemia/reperfusion injury.Methods: Myocardial ischemia/reperfusion injury was simulated by incubating primarily cultured neonatal ratcardiomyocytes in ischemic (hypoxic) ... SZB and GWLparticipated in the design of the study and did most of the experiments,LNW and HL conceived of the study, YJZ, WHZ and YL participated in itsdesign and coordination, YT, BFY, GDY,...
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Báo cáo y học: "Pain as a symptom of peripheral nerve sheath tumors: clinical significance and future therapeutic directions" potx

... NGF may mediate these effects, in part, by inducing cancer cells to invade the perineurium,a great deal of evidence suggests that NGF may directlyinduce hypersensitivity in sensory neurons in ... dichotomy seen clinically between pressure inducedpain (which occurs in both benign and malignanttumors) and rest pain (largely a symptom of malignancy)suggests that these types of pain might result ... early as possible in theclinical work-up and management of these lesions, as theyare treated very differently, and exhibit very different clin-ical and intraoperative behaviors. Ideally, the...
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Báo cáo y học: "Free functional gracilis muscle transfer in children with severe sequelae from obstetric brachial plexus palsy" potx

... analyse the proportion and quality of newly myelinated nerve fibers. Only when theneuropathologist was convinced with a good regenerativecapacity ie a substantial proportion of newly myelinatedfibers, ... between 6 and 13 years.Before surgery, all children had recovered active wrist and finger extension, which are both mandatory requirementsprior to surgery to stabilize the wrist and allow fingerrelease. ... childrenhad been initially treated elsewhere, and did not undergoearly exploration and/ or early microsurgical reconstruc-tion, focusing specially on the lower trunk. They wereoperated in our Unit...
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Báo cáo y học: "Atypical presentation of acute pancreatitis in a man with pancreatic insufficiency and cystic fibrosis: a case report" pptx

... malignancy was found.The patient contin ued to e xperience abdominal pain and ursodeoxycholic acid was introduced to treat anypotential contribution of biliary sludging to cholestasis and also to minimize ... pancreatitisoccurring in an older adult with pancreatic insufficiency and cystic fibrosis but in the setting of normal amylase and l ipase. The few reports available concerning acutepancreatitis in patients ... protein 66 g/L, albumin 36 g/L, alkalinephosphates (ALP) 809IU/L, alanine transaminase (ALT)543IU/L, glutamyl transaminase (GGT) 334IU/L, and bilirubin 23 mmol/L. His serum amylase (42IU/L) and lipase...
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