Báo cáo y học: "Vaccination with live attenuated simian immunodeficiency virus causes dynamic changes in intestinal CD4+CCR5+ T cells" pot

... nef -attenuated SIV vaccine in the cynomolgus macaque model. These data have revealed that vaccination results in dramatic dynamic changes in key lymphocyte subsets in the intestinal tract that appear ... Stebbings 1* Abstract Background: Vaccination with live attenuated SIV can protect against detectable infection with wild-type virus. We have investigated whether tar...

Ngày tải lên: 13/08/2014, 01:20

... why are they not being used? Abbreviations CCO, continuous cardiac output; CO, cardiac output; COtd, bolus thermodilution cardiac output; PAC, pulmonary artery catheter. Competing interests MRP ... output’ they discuss at length the problems of response time when using the continuous method [5]. Dr Pinsky refers in his letter to a paper by de Wilde and colleagues [4], which has a parti...

Ngày tải lên: 14/08/2014, 07:21

... 313:523-526. doi:10.1186/1742-4690-8-4 Cite this article as: Etienne et al.: Characterization of a new simian immunodeficiency virus strain in a naturally infected Pan troglodytes troglodytes chimpanzee with AIDS related symptoms. ... detected in January and nose bleeding in March. In August 2009, an eye infection (inflammation, weeping and pain) was noted; and, despite treatm...

Ngày tải lên: 13/08/2014, 01:20

... 10 days post-immunization, is greater than that observed at later time points, most probably indicating depletion or exhaustion of the anti- gen depot. A very recent work states that antigen ... vast majority of sporozoites reach the liver shortly after inoculation, strengthening the hypothesis that most of the induction of immune cells occurs in the liver. Regarding effector memory CD4 +...

Ngày tải lên: 11/08/2014, 08:21

... sugar binding site of the two lectins and thus inhibit the binding of P. aeruginosa. Methods: 11 adult CF patients with chronic infection with P. aeruginosa were treated twice daily with inhalation ... anti-inflammatory effect. Interestingly we only ob- served a significant reduction of TNFα serum protein levels with inhalation alone but not with combination therapy. It is tempt...

Ngày tải lên: 03/11/2012, 11:48

... with reduced NF-κB activity. The data support the view that IFN-β is a potential therapy for RA that might help to diminish both joint inflammation and destruction by cytokine modulation. Keywords: ... effects on tyrosine kinase signalling pathways in HL-60 cells [31]. Thus, IFN-β treatment may represent a potentially therapeutic strategy in inhibiting bone degrada- tion in arthritis....

Ngày tải lên: 09/08/2014, 01:23

... level, for the env variants, indicating that t he progeny viruses were shed via these secondary routes. It needs to be noted that the gastroin- testinal and urinary tract, but not the saliv ary glands, were ... point mutations at 31 locations were identi- fied, including mutations in the enhancer region. Inter- estingly, 12 mutation sites had been described previously in FeLV-infected c...

Ngày tải lên: 12/08/2014, 23:23

... recognize changes in circulating nutrients, mainly glucose, through a sensor system that facilitate s the metabolism o f glucose in these cells and then the synthesis and secretion of insulin. In contrast with ... during rat ontogenesis in an attempt to uncover whether developmental changes in this enzyme can explain the above alterations in insulin secretion in the fetus....

Ngày tải lên: 31/03/2014, 15:20

... features of footwear that may be of benefit to foot health for people with RA in relation to their needs. Animportantfactorthatwasnotincludedintothe current study was direct or indirect costs. The ... limitations to this study that warrant discussion. The patients were recruited from one large city hospital during the summer months. The findings may not be a true representation of footwea...

Ngày tải lên: 10/08/2014, 21:24

... important components are HLA-restricted specific cytotoxic T lymphocytes (CTLs). As EBV can switch dir ectly from the latent state into the lytic cycle without any expres- sion of further latent ... function. In this study, we found the dimerization do main was h ighly conserved without any AA mutations, suggesting its critical func- tion in the lytic activation. DNA binding domain was...

Ngày tải lên: 12/08/2014, 02:20