Báo cáo y học: "A nuclear export signal within the structural Gag protein is required for prototype foamy virus replication" pdf

... functionally trans-complement that of PFV G ag, the latter was replaced by the NES of HIV-1 Rev. The A PFV Gag (Prototype Foamy virus) SFVͲ1 Gag (Simian Foamy virus 1) SFVͲ3 Gag (Simian Foamy virus 3) HIVͲ1Rev RSV ... Saïb 1,3* Abstract Background: The Gag polyproteins play distinct roles during the replication cycle of retroviruses, hijacking many cellular machineries to fulfil...

Ngày tải lên: 13/08/2014, 01:20

... This was previously observed for another schistosome nuclear receptor, SmRXR [23], and probably reflects the high level of protein synthesis characteristic of these stages. Interest- ingly, the ... corresponding to the theoretical molecu- lar mass of the protein and to the protein synthesized in vitro in rabbit reticulocyte lysates. Interestingly, the levels of receptor...

Ngày tải lên: 23/03/2014, 21:20

... polymerase and bacterial-type plastid RNA polym- erase (PEP) [18]. The former is a single-subunit (phage-type) enzyme of nuclear origin, whereas the latter is a multisub- unit (bacterial-type) ... vitro-synthesized small subunit precursor of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco pSSU; not shown) was used [34], which is a prototype nuclear- encoded protein l...

Ngày tải lên: 24/03/2014, 04:21

... 14:R130 http://ccforum.com/content/14/4/R130 Page 4 of 8 underlying physiology, there is a combination of physio- logical factors predisposing a patient for hyperglycaemia in acute illness, during which hyperglycaemic mecha- nisms in stress ... M: The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability. Crit Care 2008, 12:R129. 40. Rattanataweebo...

Ngày tải lên: 25/10/2012, 10:02

... patients. Therefore, there is a substantial need for new therapeutic options. Because of their relatively low systemic toxicity, vitamin C (VC) and vitamin K 3 (VK 3 ), have been evaluated for their ... with one patient continuing for more than 2 years. Therapy was not discontinued in any patient due to vitamin toxicity or for other safety reasons. The PSA values of these...

Ngày tải lên: 08/08/2014, 17:20

... flow cytometry. For the analyses, a two-parameter histogram with the forward- angle light scatter and side scatter presented on the x axis and the y axis, respectively, is used to position the ... protease inhibitors to the catalytic site of the activated forms of the enzymes. In the present work, we have measured by flow cytometry the net proteolytic activity in syn...

Ngày tải lên: 09/08/2014, 08:22

... gametophyte (pollen) development is dominated by the activity of MIKC*-group genes (blue) and the development of the female gametophyte (embryo sac), embryo and seed is mainly controlled by type ... plants, so that they were somewhat the ‘dark matter of the MADS universe’.  is is in part due to the fact that the type I genes were fi rst identifi ed by genomic studies ra...

Ngày tải lên: 09/08/2014, 20:22

... assembled effectively. Electrophoretic karyotyping showed distinct chromosomal polymorphisms between isolates 0-1 and 15A, and cytological karyotyping confirmed the presence of at least nine chromosomes. The ... level about the mechanisms of P. teres pathogenicity, with neither the mechanism of virulence nor host resistance known. A genome assembly offers a powerful resource to assist...

Ngày tải lên: 09/08/2014, 22:23

... assemblies compared to the reference assembly. The coverage of raw bases for the reference assembly is 6.6-fold, for the 454/Newbler assembly 14-fold, and for the Illumina/SOAP assembly 74-fold. Table ... to other plat- forms. This manifested in our analysis as a higher dele- tion rate in the 454/Newbler assembly than the Illumina/SOAP assembly and the reference assemb...

Ngày tải lên: 09/08/2014, 22:24

... truncated YgfZ totally lost the ability to rescue plumbagin resistance in the ΔygfZ strain. This result is c onsistent with the expec tation that this region is crucial for the YgfZ function. To further ... plumbagin toxicity by detoxifying the superoxide. On t he other hand, in view of the fact that plumbagin is degraded by E. coli, it is then reasonable to hypothesize...

Ngày tải lên: 10/08/2014, 05:21