Báo cáo y học: "A nuclear export signal within the structural Gag protein is required for prototype foamy virus replication" pdf

... functionally trans-complement that of PFV G ag, the latter was replaced by the NES of HIV-1 Rev. The APFV Gag (Prototype Foamy virus) SFVͲ1 Gag (Simian Foamy virus 1)SFVͲ3 Gag (Simian Foamy virus 3)HIVͲ1RevRSV ... Saïb1,3*AbstractBackground: The Gag polyproteins play distinct roles during the replication cycle of retroviruses, hijacking manycellular machineries to fulfill them. In the case of the prototype foamy virus (PFV), Gag ... NES within the p10 domain of the Gag polypro-tein, resulting in nuclear export of Gag- RNA complexes[52,53]. Remarkably, prior to Gag synthesis, nuclear export of intron-containing RNA likely...

Báo cáo Y học: A functionally conserved member of the FTZ-F1 nuclear receptor family from Schistosoma mansoni doc

... This was previouslyobserved for another schistosome nuclear receptor,SmRXR [23], and probably reﬂects the high level of protein synthesis characteristic of these stages. Interest-ingly, the ... corresponding to the theoretical molecu-lar mass of the protein and to the protein synthesizedin vitro in rabbit reticulocyte lysates. Interestingly, the levelsof receptor protein vary considerably throughout ... constructed phylogenetic treesrooted to the mouse GCNF1 nuclear receptor. The latter is the only member of the nuclear receptor subfamily 6 [1],which is most closely related to the FTZ-F1 subfamily.Figure...

Báo cáo Y học: A nuclear-encoded CK2-type chloroplast enzyme with redox-sensitive function docx

... polymerase and bacterial-type plastid RNA polym-erase (PEP) [18]. The former is a single-subunit (phage-type)enzyme of nuclear origin, whereas the latter is a multisub-unit (bacterial-type) ... vitro-synthesizedsmall subunit precursor of ribulose-1,5-bisphosphatecarboxylase/oxygenase (Rubisco pSSU; not shown) was used[34], which is a prototype nuclear- encoded protein localizedto the ... test the biochemical similaritybetween recombinant cpCK2a and authentic PTK wasbased on ﬁndings that the latter is selectively inhibited byGSH, but not by either the oxidized form (GSSG) or otherreductants...

Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"

... 14:R130http://ccforum.com/content/14/4/R130Page 4 of 8underlying physiology, there is a combination of physio-logical factors predisposing a patient for hyperglycaemiain acute illness, during which hyperglycaemic mecha-nisms in stress ... M: The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability. Crit Care 2008, 12:R129.40. Rattanataweeboon P, Vilaichone W, Vannasaeng S: Stress hyperglycemia ... acquiredhyperglycaemia, is a temporary disorder of glucosehomeostasis, caused by failure of beta-cells to overcomeinsulin resistance created by the anti-insulin hormonessecreted by the placenta...

Báo cáo y học: "A 12 Week, Open Label, Phase I/IIa Study Using Apatone® for the Treatment of Prostate Cancer Patients Who Have Failed Standard Therapy" pps

... patients. Therefore, there is a substantial need for new therapeutic options. Because of their relatively low systemic toxicity, vitamin C (VC) and vitamin K3 (VK3), have been evaluated for their ... with one patient continuing for more than 2 years. Therapy was not discontinued in any patient due to vitamin toxicity or for other safety reasons. The PSA values of these patients were checked ... a synergistic increase in antitumor activity.8,20 These results suggest that Apatone may find use in the clinic as a co-adjuvant therapy potentially in addition to docetaxol. Our decision...

Báo cáo y học: "A novel approach to measure the contribution of matrix metalloproteinase in the overall net proteolytic activity present in synovial fluids of patients with arthritis" pptx

... flow cytometry. For the analyses, a two-parameter histogram with the forward-angle light scatter and side scatter presented on the x axis and the y axis, respectively, is used to position the ... protease inhibitors to the catalytic site of the activated forms of the enzymes. In the present work, we have measured by flow cytometry the netproteolytic activity in synovial fluids (SF) collected ... activity allows, in the case ofproteases, one to specifically account for the presence ofenzymatic inhibitors in SF. This is a key issue as the degrada-tion of the tissue architecture and disease...

Báo cáo y học: "A hitchhiker’s guide to the MADS world of plants" pptx

... gametophyte (pollen) development is dominated by the activity of MIKC*-group genes (blue) and the development of the female gametophyte (embryo sac), embryo and seed is mainly controlled by type ... plants, so that they were somewhat the ‘dark matter of the MADS universe’.  is is in part due to the fact that the type I genes were ﬁ rst identiﬁ ed by genomic studies rather than by forward genetics, ... eukaryotes [4].  ese two types are distinguished on the basis of sequence dissimilarity and also diﬀ er in sequence speciﬁ city in DNA binding and the amount of DNA bending that they induce...

Báo cáo y học: "A first genome assembly of the barley fungal pathogen Pyrenophora teres f. teres" ppt

... assembledeffectively. Electrophoretic karyotyping showed distinct chromosomal polymorphisms between isolates 0-1 and15A, and cytological karyotyping confirmed the presence of at least nine chromosomes. The ... level about the mechanisms of P. teres pathogenicity, with neither the mechanism of virulence nor host resistance known. Agenome assembly offers a powerful resource to assist the dissection of ... isolate 0-1. The assembly was validated by comparison to BAC sequences,ESTs, orthologous genes and by PCR, and complemented by cytogenetic karyotyping and the first genome-widegenetic map for P....

Báo cáo y học: "A vertebrate case study of the quality of assemblies derived from next-generation sequence" doc

... assemblies compared to the reference assembly. The coverage of raw bases for the referenceassembly is 6.6-fold, for the 454/Newbler assembly 14-fold, and for the Illumina/SOAP assembly 74-fold.Table ... to other plat-forms. This manifested in our analysis as a higher dele-tion rate in the 454/Newbler assembly than the Illumina/SOAP assembly and the reference assembledwith PCAP, despite the ... heterozygosity and ploidy,as well as the sequencing platform used to generate the primary data. Over the past decade most large (>1 Gbp)genomes were sequenced exclusively on capillary-basedSanger...

Báo cáo y học: "A role of ygfZ in the Escherichia coli response to plumbagin challenge" pdf

... truncated YgfZ totally lost the abilityto rescue plumbagin resistance in the ΔygfZ strain. Thisresult is c onsistent with the expec tation that this region is crucial for the YgfZ function.To further ... plumbagintoxicity by detoxifying the superoxide. On t he otherhand, in view of the fact that plumbagin is degraded byE. coli, it is then reasonable to hypothesize that YgfZ andSodA may counteract ... plumba-ginresistanceintheΔygfZ strain was regained partially(Figure 5B). Since there is only a low degree of identitybetween Rv0811c and YgfZ, it is not clear whether the former is a real counterpart of the...

Xem thêm

Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thống Một số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTP Nghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THz Nghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt nam Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit ĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN Nghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúng Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khí Chuong 2 nhận dạng rui ro Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vật Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vật chuong 1 tong quan quan tri rui ro Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Trách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM