Báo cáo y học: "Disease-associated XMRV sequences are consistent with laboratory contamination" pot
Báo cáo y học: "Disease-associated XMRV sequences are consistent with laboratory contamination" pot
... com-
monly carry retroviruses that can be amplified with pri-
mers erroneously described as specific to XMRV [4,5].
Phylogenetic analysis of XMRV sequences
Analysis of the genetic diversity and phylogenetic ... lack of XMRV genetic diver-
sity is incompatible with this possibility.
Whilst our observations can not conclusively prove
that XMRV is not a human pathogen they appear
c...
Báo cáo y học: "Proton-pump inhibitors are associated with a reduced risk for bleeding and perforated gastroduodenal ulcers attributable to non-steroidal anti-inflammatory drugs: a nested case-control study" pptx
... the efficacy and safety of selective COX-2
inhibitors were conducted in relatively young, healthy subjects.
Our study suggests that these may not be the patients who are
especially at risk for ... criteria are maintained,
and those at high risk for drug side effects or complications
are usually excluded. Conversely, in daily clinical practice, it is
especially at-risk patients who are...
Báo cáo y học: "Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases" potx
... DeWoody K,
Williamson P, Braun J, Ankylosing Spondylitis Study for the Evaluation of
Recombinant Infliximab Therapy Study Group: Efficacy and safety of
infliximab in patients with ankylosing spondylitis: ... 7
Abbreviations
ATI: antibody toward infliximab; BASDAI: Bath Ankylosing Spondylitis Disease
Activity Index; CRP: C-reactive protein; ELISA: enzyme-linked immunosorbent
assay; ESR: eryt...
Báo cáo y học: " Zangfu zheng (patterns) are associated with clinical manifestations of zang shang (target-organ damage) in arterial hypertension" pot
... azing
upwards (gan huo shang yan) (13-17%), qi and blood
deficiency leading to Liver yang rising (qi xue xu gan
yang shang yan) (2-6%) and Kidney-yin/yang deficiency
(shen yin yang xu)(0-3%).Guet al. ... converting enzyme inhibitors for yin-defi-
ciency and yang-hype ractivity or combine d liver-yin and
kidney-yin deficiency [22]. The therapeutic potential of
several antihypertensive agents (...
Báo cáo y học: "Prevalence of psychomorbidity among patients with chronic cough" potx
... response.
Secondly, the specific psychological profile of patients
may influence their perception of symptoms. Patients
with anxiety, depression and hypochondriasis are more
aware of their body's physiology, ... the study population compared with norms estab-
lished by Spielberger [8] are displayed in table 1. Trait
anxiety was significantly higher among all coughers com-
pared t...
Báo cáo y học: "PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA1/2-associated breast cancers"
... [poly(ADP-ribose) polymerase-1] inhibitors kill breast cancer
associated gene-1 and –2 (BRCA1/2) deficient cells with extremely high efficiency while BRCA+/- and
BRCA+/+ cells are relatively ... the human breast
cancer susceptibility gene brca2. J Biol Chem 1997; 272: 31941-4.
29. Bryant HE, and Helleday T. Poly(ADP-ribose) polymerase
inhibitors as potential chemotherapeutic agents....
Báo cáo Y học: Rodent a-chymases are elastase-like proteases pot
... analysis and
detailed structural analysis for MCP-5-chymostatin com-
plex by X-ray crystallography, are necessary to clarify the
mechanism of the inhibition.
Site-directed mutagenesis analysis ... in human chymase [37,38]. They
hydrolyzed the methylated substrate MeO-succinyl-Ala-
Ala-Pro-Val-pNA more effectively than the unmethylated
succinyl-Al-Ala-Pro-Val-pNA, predominantly due to the
lo...
Báo cáo y học: "QTc and psychopharmacs: are there any differences between monotherapy and polytherapy" ppsx
... the study. The monotherapy group
was consisted of thirty-two women treated with an antipsychotic or an antidepressant while the
polytherapy group was composed of twenty-nine women treated with an ... purposes)
Annals of General Psychiatry
Open Access
Primary research
QTc and psychopharmacs: are there any differences between
monotherapy and polytherapy
Jadranka Жulav Sumić*, Vesna Barić...
Báo cáo y học: "NPAS2 and PER2 are linked to risk factors of the metabolic syndrome" pps
... 0.05).
Statistical analysis
Genotype frequencies, allele frequencies and Hardy-
Weinberg p-values were calculated with the Pearson exact
test. Only those haplotypes occurring with a frequency
>0.05 were ... cir-
cadian clock are the light-dark transitions, while the
peripheral clocks are set by metabolic signals in response
to feeding cycles [3]. With shortage of daylight, the me...
Báo cáo y học: "Early Migrating leukocytes are the source of Peroxiredoxin V during inflammation in the airway" potx
... inflammation, multiple
leukocytes appeared in the lung parenchyma, most of
which highly expressed PRXV (Figure 2). Therefore, infil-
tration of the lung parenchyma with leukocytes resulted
in an enhanced ... results are in agree-
ment with our data.
In studies of secreted PRXV, we observed only a 60 kDa
band by Western blot analyses. Peroxiredoxins may form
polymers in an oxidized state...
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