Báo cáo y học: "Disease-associated XMRV sequences are consistent with laboratory contamination" pot
Báo cáo y học: "Disease-associated XMRV sequences are consistent with laboratory contamination" pot
... com- monly carry retroviruses that can be amplified with pri- mers erroneously described as specific to XMRV [4,5]. Phylogenetic analysis of XMRV sequences Analysis of the genetic diversity and phylogenetic ... lack of XMRV genetic diver- sity is incompatible with this possibility. Whilst our observations can not conclusively prove that XMRV is not a human pathogen they appear c...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: "Proton-pump inhibitors are associated with a reduced risk for bleeding and perforated gastroduodenal ulcers attributable to non-steroidal anti-inflammatory drugs: a nested case-control study" pptx
... the efficacy and safety of selective COX-2 inhibitors were conducted in relatively young, healthy subjects. Our study suggests that these may not be the patients who are especially at risk for ... criteria are maintained, and those at high risk for drug side effects or complications are usually excluded. Conversely, in daily clinical practice, it is especially at-risk patients who are...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases" potx
... DeWoody K, Williamson P, Braun J, Ankylosing Spondylitis Study for the Evaluation of Recombinant Infliximab Therapy Study Group: Efficacy and safety of infliximab in patients with ankylosing spondylitis: ... 7 Abbreviations ATI: antibody toward infliximab; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; CRP: C-reactive protein; ELISA: enzyme-linked immunosorbent assay; ESR: eryt...
Ngày tải lên: 12/08/2014, 17:22
Báo cáo y học: " Zangfu zheng (patterns) are associated with clinical manifestations of zang shang (target-organ damage) in arterial hypertension" pot
... azing upwards (gan huo shang yan) (13-17%), qi and blood deficiency leading to Liver yang rising (qi xue xu gan yang shang yan) (2-6%) and Kidney-yin/yang deficiency (shen yin yang xu)(0-3%).Guet al. ... converting enzyme inhibitors for yin-defi- ciency and yang-hype ractivity or combine d liver-yin and kidney-yin deficiency [22]. The therapeutic potential of several antihypertensive agents (...
Ngày tải lên: 13/08/2014, 14:20
Báo cáo y học: "Prevalence of psychomorbidity among patients with chronic cough" potx
... response. Secondly, the specific psychological profile of patients may influence their perception of symptoms. Patients with anxiety, depression and hypochondriasis are more aware of their body's physiology, ... the study population compared with norms estab- lished by Spielberger [8] are displayed in table 1. Trait anxiety was significantly higher among all coughers com- pared t...
Ngày tải lên: 13/08/2014, 08:20
Báo cáo y học: "PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA1/2-associated breast cancers"
... [poly(ADP-ribose) polymerase-1] inhibitors kill breast cancer associated gene-1 and –2 (BRCA1/2) deficient cells with extremely high efficiency while BRCA+/- and BRCA+/+ cells are relatively ... the human breast cancer susceptibility gene brca2. J Biol Chem 1997; 272: 31941-4. 29. Bryant HE, and Helleday T. Poly(ADP-ribose) polymerase inhibitors as potential chemotherapeutic agents....
Ngày tải lên: 31/10/2012, 16:57
Báo cáo Y học: Rodent a-chymases are elastase-like proteases pot
... analysis and detailed structural analysis for MCP-5-chymostatin com- plex by X-ray crystallography, are necessary to clarify the mechanism of the inhibition. Site-directed mutagenesis analysis ... in human chymase [37,38]. They hydrolyzed the methylated substrate MeO-succinyl-Ala- Ala-Pro-Val-pNA more effectively than the unmethylated succinyl-Al-Ala-Pro-Val-pNA, predominantly due to the lo...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo y học: "QTc and psychopharmacs: are there any differences between monotherapy and polytherapy" ppsx
... the study. The monotherapy group was consisted of thirty-two women treated with an antipsychotic or an antidepressant while the polytherapy group was composed of twenty-nine women treated with an ... purposes) Annals of General Psychiatry Open Access Primary research QTc and psychopharmacs: are there any differences between monotherapy and polytherapy Jadranka Жulav Sumić*, Vesna Barić...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "NPAS2 and PER2 are linked to risk factors of the metabolic syndrome" pps
... 0.05). Statistical analysis Genotype frequencies, allele frequencies and Hardy- Weinberg p-values were calculated with the Pearson exact test. Only those haplotypes occurring with a frequency >0.05 were ... cir- cadian clock are the light-dark transitions, while the peripheral clocks are set by metabolic signals in response to feeding cycles [3]. With shortage of daylight, the me...
Ngày tải lên: 10/08/2014, 09:20
Báo cáo y học: "Early Migrating leukocytes are the source of Peroxiredoxin V during inflammation in the airway" potx
... inflammation, multiple leukocytes appeared in the lung parenchyma, most of which highly expressed PRXV (Figure 2). Therefore, infil- tration of the lung parenchyma with leukocytes resulted in an enhanced ... results are in agree- ment with our data. In studies of secreted PRXV, we observed only a 60 kDa band by Western blot analyses. Peroxiredoxins may form polymers in an oxidized state...
Ngày tải lên: 11/08/2014, 08:21