Báo cáo y học: "Mouse DNA contamination in human tissue tested for XMRV" pptx

Báo cáo y học: "Mouse DNA contamination in human tissue tested for XMRV" pptx

Báo cáo y học: "Mouse DNA contamination in human tissue tested for XMRV" pptx

... looked for XMRV sequences in DNA extracted from formalin-fixed paraffin- embedded prostate tissues. To control for contamination, PCR assays to detect either mouse mitochondrial DNA (mtDNA) or intracisternal ... cautionary tale of virus and disease. BMC Biol 2010, 8:24. doi:10.1186/1742-4690-7-108 Cite this article as: Robinson et al.: Mouse DNA contamination in human tiss...

Ngày tải lên: 13/08/2014, 01:20

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Báo cáo y học: "Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels" ppt

Báo cáo y học: "Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels" ppt

... activity of MBD4 (methyl-CpG binding domain pro- tein 4), another thymine glycosylase involved in removing T/G mismatches [17]. Most studies in the field of active DNA demethylation are based on ... be required for the hormone-dependent demethylation of the CYP27B1 gene, suggesting that cytosine deamination may not necessarily be required for demethylation [17]. Another study argued...

Ngày tải lên: 09/08/2014, 20:22

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Báo cáo Y học: Regulation of RAS in human platelets Evidence that activation of RAS is not sufficient to lead to ERK1-2 phosphorylation pot

Báo cáo Y học: Regulation of RAS in human platelets Evidence that activation of RAS is not sufficient to lead to ERK1-2 phosphorylation pot

... GPVI, glycoprotein VI; PtdIns3K, phosphatidylinositol 3-kinase; PVDF, poly(vinylidene difluoride); PKC, protein kinase C; PP1, (4-amino-4-(4-methylphe- nyl)-7-(t-butyl)pyrazola[3,4-d]pyrimidine); ... Furthermore, these proteins can be activated independently, suggesting that each link is func- tional [5–7]. In addition, in megakaryocytic cell lines and in primary megakaryocytes, the prec...

Ngày tải lên: 08/03/2014, 16:20

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Báo cáo y học: "Progress and Challenges in the Understanding of Chronic Urticaria" pptx

Báo cáo y học: "Progress and Challenges in the Understanding of Chronic Urticaria" pptx

... antibodies against the eosinophil low-affinity IgE receptor (CD23), which activate eosinophils and induce histamine release by eosinophie cationic protein (ECP), major basic protein (MBP), or other eosinophil ... that the cytokine phenotype reflects the physiologic potential for cellular cytokine production. The cytokine profile found in our study does not reflect either a Th1 or a Th2 pr...

Ngày tải lên: 08/08/2014, 21:20

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Báo cáo y học: "Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia" pptx

Báo cáo y học: "Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia" pptx

... A: Induction by inter- leukin-7 of lymphokine-activated killer activity in lymphocytes from autologous and syngeneic marrow transplant recipients before and after systemic interleukin-2 therapy. ... primary abnormality. Therefore, supplementation with recombinant IL-7 may be necessary to improve lymphocyte reconstitution in lympho- penic RA patients, with the caveat that this cytokine is...

Ngày tải lên: 09/08/2014, 06:22

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Báo cáo y học: "Degradome expression profiling in human articular cartilage" potx

Báo cáo y học: "Degradome expression profiling in human articular cartilage" potx

... predominantly intracellularly [26,27]. Cathepsin H, cathepsin C, cathepsin F, cathepsin W, cathepsin B and cathepsin S are also increased in expression in OA tissue Table 3 Fold change and threshold cycle ... metalloproteinase domain; ADAMTS: a disintegrin and metalloproteinase domain with thrombospondin motifs; Ct: threshold cycle; IGF: insulin-like growth factor; IL: interleukin; MMP...

Ngày tải lên: 09/08/2014, 14:22

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Báo cáo y học: "Recent key advances in human immunodeficiency virus medicine and implications for Chin" potx

Báo cáo y học: "Recent key advances in human immunodeficiency virus medicine and implications for Chin" potx

... start- ing at 14 instead of 28 weeks and continuing through breastfeeding was added as an option. Although ART can be delivered safely without routine monitoring of hema- tology and biochemistry in ... and developing new ARV drugs, optimizing the ART delivery system, and improving therapy for non-AIDS related conditions and coinfections. Competing interests The authors declare that they h...

Ngày tải lên: 10/08/2014, 05:21

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Báo cáo y học: "Primary cardiac osteosarcoma in a 42-year-old woman" pptx

Báo cáo y học: "Primary cardiac osteosarcoma in a 42-year-old woman" pptx

... symptoms, making early diagnosis a challenge. We describe here a 42-year- old woman with a primary cardiac osteosarcoma, which was surgically removed by cardiopulmonary bypass. Two years later, ... Access Primary cardiac osteosarcoma in a 42-year-old woman Honghe Luo 1 , Yiyan Lei 1 , Chunhua Su 1 , Lie Cai 2 , Tao Wang 3 , Jianyong Zou 1 , Zhenguang Chen 1*† Abstract We describe here a 42-...

Ngày tải lên: 10/08/2014, 09:23

2 318 0
Báo cáo y học: " Bioelectrical impedance analysis in clinical practice: implications for hepatitis C therapy BIA and hepatitis C" pptx

Báo cáo y học: " Bioelectrical impedance analysis in clinical practice: implications for hepatitis C therapy BIA and hepatitis C" pptx

... well by water and electro- lyte-containing parts of a body but poorly by fat and bone mass. A fixed, low-voltage, high-frequency alter- nating current introduced into the human body or tissue is ... significant reduction in body fat in patients with genotype 3. Inter- esti ngly, majo r alter ations in BMI were not present. We suggest a loss in fatty tissue, which might be compen-...

Ngày tải lên: 12/08/2014, 04:20

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Báo cáo y học: "Smad gene expression in pulmonary fibroblasts: indications for defective ECM repair in COPD" ppsx

Báo cáo y học: "Smad gene expression in pulmonary fibroblasts: indications for defective ECM repair in COPD" ppsx

... inducing ubiquination of their receptors. Additionally, Smad7 can induce TGFβ-production by fibroblasts upon activation by pro-inflammatory cytokines like TNF and IFN-gamma, thereby enabling autocrine ... inadequate in a subset of smokers, leading to gradually increasing parenchymal ECM destruction and emphysematous changes [9]. We addressed three ques- tions to obtain more insight in the...

Ngày tải lên: 12/08/2014, 14:20

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