Báo cáo y học: "Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors" pdf
Tài liệu Báo cáo Y học: Evolution of the enzymes of the citric acid cycle and the glyoxylate cycle of higher plants pdf
... complex, the tricarboxylic acid cycle, and the glyoxylate cycle by examining t he individual phylogenies of the 21 s ubunits comprising the 14 enzymes of thesepathways as they occur in eukaryotes, ... out of style (see [26]). Sixty-fouryears later, gene- for -gene phylogenetic analysis can provideinsights into the origin of its individual enzymes.However, the study of the enzymes of the tricarboxylicacid ... compartmentalized in the glyoxysomes of plants [31], the single exception being aconitase, w hich islocalized in the c ytosol [32,33]. Here we investigate the evolution of the enzymes of the pyru vate dehydrogenase(PDH)...
- 16
- 474
- 0
Báo cáo y học: "Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors" pdf
... gag and nef in HLA-B*57 positive ES. We previously showed evolution in the gag gene of ESwhich surprisingly was mostly due to synonymous mutations rather than non-synonymous mutation in targetedCTL ... muta-tions in Nef. However, in all four patients, we saw veryfew non-synonymous mutations and a comparable fre-quency of synonymous mutations in both genes. Thisanalysis is technically challenging ... suggest that the nef and gag genes in thesepatients respond similarly to selective pressure from the host.Findings The mechanisms responsible for the control of the HIV-1 replication in elite suppressors...
- 7
- 346
- 0
Báo cáo y học: " Evolution of the uniquely adaptable lentiviral envelope in a natural reservoir host" potx
... appears to be highly glycosylated in naturallyinfected SMs. Presumably, continually evolving antibodyresponses in these natural hosts maintain a highly glyco-sylated surface protein, albeit without ... extraordinar-ily high intra-host SIVsm env V1V2 diversity in naturallyinfected SMs, maintained by its high replication rate and positive selection most likely mediated by antibodyresponses. Ongoing ... ability of emerging pathogens to infect new species is likely related to the diversity of pathogen variants present in existing reservoirs and their degree of genomic plasticity,which determines their...
- 14
- 265
- 0
Báo cáo y học: " Evolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41" pdf
... posi-tion in the interior of the gp41 core, but the orientation of their side chains differs (fig. 6). The side chain of residue593 (cyan in fig. 6) points towards the interior of the loop,thereby ... reversions in structure model of the HIV-1 gp41 ectodomain [18]Figure 6Modeling of the SOS reversions in structure model of the HIV-1 gp41 ectodomain [18]. The Cα atoms of the relevant residues are indicated ... lost by the C60 5Y substitution. Alternatively, the negative effect of the L593Q substitution in the absence of the disulfide bondcan be partially overcome by acquisition of the compen-satory Q591L...
- 11
- 393
- 0
Báo cáo y học: "Evolution of the core and pan-genome of Streptococcus: positive selection, recombination, and genome composition" pdf
... supported by the majority of genes. Finally, p values were corrected for multiple hypothe-sis testing using the Benjamini and Yekutieli method [75]. The effect of lineages, and genes' TIGR main ... theseresults, and the ambiguity of defining which genes had the same history, we analyzed each gene with its own gene tree in the subsequent positive selection analyses.Within S. pyogenesAs for ... analysisFigure 3Frequency of genes within the 26 genomes included in this analysis. Genes present in a single genome represent lineage specific genes, while at the opposite end of the scale, genes...
- 17
- 245
- 0
Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"
... state the activities of numerous interacting genes are altered which may influence the effect of PPARδ on metabolism. In our data and in the study by Skogsberg et al., the effect of the C ... by silver staining on polyacrylamid gel. Statistical Analysis Allele frequencies were determined by gene counting and compared using the א² test. The data was analysed using SPSS 12.0 software. ... haplotypes on plasma levels of lipids and progression of coronary atherosclerosis and response to statin therapy in the lipoprotein coronary atherosclerosis study. Pharmacogenet. 2004; 14:61-71....
- 4
- 568
- 0
Báo cáo Y học: Cloning of the manganese lipoxygenase gene reveals homology with the lipoxygenase gene family doc
... sequenced the gene of Mn-LOX of G. graminis and the corresponding cDNA. Our mainfinding is that Mn-LOX belongs to the LOX gene familywith a unique difference in one of the conserved regions. The deduced ... deter-mine the impact of deleting one or two amino acids in a helix 9 on the metal center and on the catalyticproperties. The corresponding studies with insertion of one or two amino acids into the ... EOr3A generated a band of 230 bp, which containedFig. 1. Organization of the Mn-LOX-Gga gene, Northern and Southernblot analyses. (A) The Mn-LOX-Gga gene. The open box indicates the protein coding...
- 8
- 424
- 0
Báo cáo y học: "Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis" pdf
... stop taking aspirin and all cytokine inhibitors 10to 14 days prior to surgery.Histology of synovial biopsies and levels of cytokinesHaematoxylin and eosin histology was performed on 26 of the OA ... Representativemicrographs of this grading system are presented in Figure 1.Quantification of inflammatory cytokines in synovial fluidCytokine profiles in synovial fluid were determined using aBD™ cytometric ... simply reflect the level of synthesis/release andcatabolism of endocannabinoids and entourage compounds in the synovium. The source of the endocannabinoids present in the synovium and synovial...
- 14
- 500
- 0
Báo cáo y học: "Disruption of the thrombospondin-2 gene alters the lamellar morphology but does not permit vascularization of the adult mouse lumbar disc" pdf
... the TSP-2 gene with respect to the morphology and cellularity of the annulus, the presence of vascular beds within the disc, andvascularity of the soft tissue margin of the disc that serves tosupply ... vascular ingrowth into discs of the TSP-2-null mice.Conclusion These data confirm a role for TSP-2 in the morphology of the disc and suggest the presence of otherinhibitors of angiogenesis in the ... thatalthough an increase in vasculature was present in the TSP-2-null tissue in the margin of the disc, vascular ingrowth into the body of the disc did not occur. Our results point to the need forfuture...
- 9
- 317
- 0
Báo cáo y học: " Substitution of the Rev-response element in an HIV-1-based gene delivery system with that of SIVmac239 allows efficient delivery of Rev M10 into T-lymphocytes" ppsx
... forintracellular immunization [2]. However, the delivery of such genes using a packaging system based on HIV-1 ishampered by the inhibitory effect of the anti -HIV-1 genes,such as Rev M10, on the ... containingconstruct. To the best of our knowledge, our study is the first to evaluate SIV RRE in the context of an HIV-1- based gene delivery system. The ability of SIV RRE to render the packaging ... decreasing recombination fre-quency between components of packaging systems is byusing hybrid packaging systems consisting of helper and gene transfer constructs derived in their entirety fromviruses...
- 13
- 357
- 0
Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyenthe evolution of the islamic capital market in malaysiaBáo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ