... permanent radioactive implants (brachytherapy) [7]. iv) The standard initial systemic therapy for locally advanced or metastatic disease is hormonal or androgen depri- vation therapy (ADT) that ... Targeting uPA/uPAR in prostate cancer. Cancer Treat. Rev. 2007;33(6):521-7 3. Catalona WJ and Smith DS. 5-year tumor recurrence rates after anatomical radical retropubic prostatecto...
Ngày tải lên: 26/10/2012, 09:48
... 10:15 http://www.annals-general-psychiatry.com/content/10/1/15 Page 3 of 6 PRIMARY RESEARCH Open Access Advanced paternal age is a risk factor for schizophrenia in Iranians Morteza Naserbakht 1 , Hamid-Reza Ahmadkhaniha 2,3,4* , ... Ahmadkhaniha 2,3,4* , Bahareh Mokri 5 and Cassandra L Smith 6 Abstract Background: Since 1958 many, but not all studies have demonstrated that...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: " ncremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study" potx
... pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study Harald E Vonkeman 1 , Louise MA Braakman-Jansen 2 , ... using the software package S-plus (TIBCO Software Inc., Palo Alto, California, USA) professional version 6.0. Cost effectiveness To calculate the increme...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia" pptx
... A: Induction by inter- leukin-7 of lymphokine-activated killer activity in lymphocytes from autologous and syngeneic marrow transplant recipients before and after systemic interleukin-2 therapy. ... primary abnormality. Therefore, supplementation with recombinant IL-7 may be necessary to improve lymphocyte reconstitution in lympho- penic RA patients, with the caveat that this cytokine is...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: " The RNA interference pathway: a new target for autoimmunity" pot
... RNAi machinery is that RNAi was initially recognized as an antiviral mechanism in plants and certain invertebrates [14]. The evolutionary conservation of RNAi suggests a similar role for RNAi in mammals, which ... Although they were initially reported to be specifically associated with systemic lupus erythematosus [7], a later study showed that auto- antibodies to the Su antigen are...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Incremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study" pptx
... vary, they all used actual primary clinical data from trials and applied them to an economic model. These data may however not always be generalised outside the con- trolled environment of the ... a pharmacoeconomic analysis linked to a case-control study Harald E Vonkeman 1 , Louise MA Braakman-Jansen 2 , Rogier M Klok 3 , Maarten J Postma 3 , Jacobus RBJ Brouwers 3 a...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: " Innate immunity and monocyte-macrophage activation in atherosclerosis" pot
... heterogeneity of originating monocytes, and the inflammatory and lipidic stimuli available in the pla- que. It is known that signalling pathways related to innate immunity are strong determinants ... It relies on two arms: innate im munity and adaptive immunity. Innate immunity is activated immediately upon encounter with the pathogen and is executed pri- marily by myeloi...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: "Establishing an implementation network: lessons learned from community-based participatory research" pptx
... BA: Commentary: Model of community health govern- ance: Applicability to community-based participatory research partnerships. Journal of Urban Health: Bulletin of the New York Academy of Medicine ... with accountability to grant agencies, peers, and promotion committees. Therefore, not only do the types of data differ between these organizations, but also the method by which they collect,...
Ngày tải lên: 11/08/2014, 05:21
Báo cáo y học: " Innate immunity and monocyte-macrophage activation in atherosclerosis" potx
... It relies on two arms: innate im munity and adaptive immunity. Innate immunity is activated immediately upon encounter with the pathogen and is executed pri- marily by myeloid cells with the participation ... of Ly6C + into Ly6C - monocytes. Other mechanisms proposed for this increase in Ly6C + monocytes during hypercholesterole- mia include in creased proliferation and reduc...
Ngày tải lên: 11/08/2014, 06:22
Báo cáo y học: "Expression of Ebolavirus glycoprotein on the target cells enhances viral entry" pptx
... expression of EGP on the target cells enhances viral entry via the fusion machinery, GP2. In contrast, high level expression of EGP on the target cells can sequester the Ebola receptor(s) by RBD of ... (bidirectional) may be more efficient than the GP2 on the viral mem- brane alone (unidirectional) in mediating viral/ cell mem- brane fusion. Second, phys...
Ngày tải lên: 12/08/2014, 04:21
Báo cáo y học: "Innate immunity triggers IL-32 expression by fibroblast-like synoviocytes in rheumatoid arthritis" ppsx
... of inflammatory reactions in RA, by expressing IL-32, which in turn induces the expression of TNF-α, IL-1, or IL-18 by macrophages or dendritic cells, bridging innate and adaptive immunity. IL-32 ... expressed by FLSs, and their expression is increased in response to inflammatory stimuli [15,16]. FLSs exert a pro-inflammatory activity, essentially by synthesizing cytoki...
Ngày tải lên: 12/08/2014, 14:22
Báo cáo y học: " Editorial The sound of silence: rationing resources for critically ill patients" pptx
... sense of conflict for us, we are most likely to become aware of our daily rationing deci- sions if we make them in light of both responsibilities. Whether autonomy, utility and equity (or any other ... 350:7–12. Editorial The sound of silence: rationing resources for critically ill patients Cook and Giacomini R3 suggest a modest rationing framework based on th...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: " Innate immunity against HIV: a priority target for HIV prevention research" ppt
... MJ, Pandrea I, Faye A, Onanga R, Apetrei C, Poaty- Mavoungou V, Rouquet P, Estaquier J, Mortara L, et al: Antiinflammatory profiles during primary SIV infection in African green monkeys are associated ... therapeutically at a systemic level. Likewise protection could also be afforded by direct ad ministration of agents able to block the activity of innate pathways that promote HIV repl...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: " APOBEC3G-UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replication" pot
... 5' primer used was 5'- ATCCAAGACGGAATTCACGCCGCAGGAGAAA- GAAGCTATAG-3'; the 3' primer for the APOPEC3G-UBA2 fusion was 5'-ATCGTACTCGAAGCTTCTAACTCAGGAG- GAAGTTGGCAG-3'; ... Access Research APOBEC3G- UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replication Lin Li 1,4 , Dong Liang 1 ,...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo y học: "Inhaled activated protein C: a new therapy for the prevention of ventilator-induced lung injury" docx
... 1667. doi:10.1186/cc8977 Cite this article as: Abraham E: Inhaled activated protein C: a new therapy for the prevention of ventilator-induced lung injury? Critical Care 2010, 14:144. Abraham Critical Care 2010, 14:144 ... 204:2439-2448. 6. Bae JS, Yang L, Rezaie AR: Receptors of the protein C activation and activated protein C signaling pathways are colocali...
Ngày tải lên: 13/08/2014, 20:21