Báo cáo y học: "HIV-1 subtype distribution in the Gambia and the significant presence of CRF49 cpx, a novel circulating recombinant form" pdf
Báo cáo y học: "HIV-1 subtype distribution in the Gambia and the significant presence of CRF49_cpx, a novel circulating recombinant form" pdf
... data and participated in writing the manuscript, CO participated in designing the sequencing strategy and methods and assisted in the initial analysis of the sequences, BF helped interpret the ... each non -recombinant fragment. Recombinant map of CRF49_ cpx (top) drawn using the Recombinant HIV-1 Drawing Tool at LAHDB and depicting HXB2 numbering at breakp...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: " Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination" pps
... mainly because of the complex anatomy of the central nervous system and the unavailability of physiological para- meters [54, 55]. Whereas the mechanisms involved in drug disposition into brain are ... (N CYP450 in nmol): amount of cytochrome P450; (P app, ab in dm/min): apical to basolateral apparent permeability through the Caco-2 monolayer; (P app, ba in dm/min)...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: "Distinct synovial immunopathology in Behçet disease and psoriatic arthritis" pot
... 130:46-54. 31. Yasuoka H, Okazaki Y, Kawakami Y, Hirakata M, Inoko H, Ikeda Y, Kuwana M: Autoreactive CD8 + cytotoxic T lymphocytes to major histocompatibility complex class I chain-related gene A in patients ... vessels as well as expression of perforin and granzyme. The stained slides were evaluated by digital image analysis. Results The global degree of synovial inflamm...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "Cartilage-specific autoimmunity in animal models and clinical aspects in patients – focus on relapsing polychondritis" ppsx
... whereas the LEW. 1A rat, carrying the same MHC alleles as the DA rat, was a high responder [3]. In the murine models, preliminary data indicate that similar strains, carrying the Q haplotype, ... that have not yet been investigated in RP patients. Adjuvants and oils can induce arthritis in many rat strains [33–36] and auricular chondritis in Wistar rats [21]. Finally,...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Most recent developments in strategies to reduce the progression of structural changes in osteoarthritis: today and tomorrow" doc
... composed of at least three main and distinct signalling pathways: the extracellular signal-regulated protein kinases, the c-Jun amino-terminal kinases or stress-activated protein kinases, and the ... among the inflammatory factors the proinflammatory cytokine IL-1β plays a central role in OA pathophysiology. Factors that regulate its synthesis and/ or activity are therefo...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Progesterone - new therapy in mild carpal tunnel syndrome? Study design of a randomized clinical trial for local therapy" pptx
... in the hand distribution of the median nerve, more often occurring during night or in early morning waking up the patients. There may be also sensory loss and hand weak- ness and clumsiness causing ... Neurophysiology Clinic Section, University of Siena, Siena, Italy Full list of author information is available at the end of the article Milani et al. Journal of...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: " Assessing cognitive insight in nonpsychiatric individuals and outpatients with schizophrenia in Taiwan: an investigation using the Beck Cognitive Insight Scale" ppsx
... reliability, correlation analyses, and discriminative validity. Results: The BCIS showed adequate internal consistency and stability over time. Exploratory and confirmatory factor analyses on the ... study. YCK analyzed the data further and wrote the final manuscript. YPL helped to draft and revised the manuscript. All authors read and approved the paper. Competing int...
Ngày tải lên: 11/08/2014, 16:20
Báo cáo y học: " Endothelial cell apoptosis in chronically obstructed and reperfused pulmonary artery" pps
... a sham- operated group (n = 5). PA vasoreactivity was studied and eNOS assayed. EC apoptosis was assessed by TUNEL in the proximal and distal PA and by caspase-3 activity assay in the proximal PA. ... is triggered and modulated by two pathways. The intrinsic pathway involves the mitochondria and is activated by reactive oxygen species; whereas the extrinsic pathway i...
Ngày tải lên: 12/08/2014, 15:21
Báo cáo y học: "Prolonged ozone exposure in an allergic airway disease model: Adaptation of airway responsiveness and airway remodeling" pptx
... alters breathing patterns, and changes in the timing of early and late expirations (Pause) and in Penh are the results of alterations in the timing of breathing, as well as the prolongation of ... function, increases AHR, and induces airway inflammation in dogs [3], guinea pigs [4], and humans [5-7]. Chronic airway inflammation is associated with airway remod...
Ngày tải lên: 12/08/2014, 16:20
Báo cáo y học: "Epidermal wound healing in severe sepsis and septic shock in humans" pptx
... statistical analysis. VK and TIA-K helped draft the manuscript and helped conceive the study and participated in its design and coordination. JJL and AO participated in the design of the study. JS ... than in the controls [36,37]. Early sepsis is characterised by hyper-inflammation and excess of pro- inflammatory mediators such as tumour necrosis factor-alpha...
Ngày tải lên: 13/08/2014, 16:21