Báo cáo y học: "Structural features in the Rous sarcoma virus RNA stability element are necessary for sensing the correct termination codon" potx

... Access Structural features in the Rous sarcoma virus RNA stability element are necessary for sensing the correct termination codon Johanna B Withers, Karen L Beemon * Abstract Background: Nonsense-mediated mRNA ... and Beemon: Structural features in the Rous sarcoma virus RNA stability element are necessary for sensing the correct...

Ngày tải lên: 13/08/2014, 01:20

... RGWXNYY motif, in which the Y3 54 and Y3 55 amino acids were replaced by alanine residues, and the 2.5· mutant [27], in which the IEP was truncated in the RT domain. Therefore, the pattern of inhibition ... The products expected from partial reverse splicing of the intron RNA into the insertion site in the DNA are shown at the top. Solid lines indicate DNA an...

Ngày tải lên: 15/03/2014, 09:20

... n. These latter two quantities are asymptotically zero in the CRP, while they are constant or infinite in the model of Gerstein and coworkers. The last two columns indicate the resulting scaling ... domains. Assuming they do not, in order for their domain classes to increase lin- early with n, they have to be added with constant probability, as in the model of Gerstei...

Ngày tải lên: 14/08/2014, 21:20

... meninges [1]. This tumor is generally rare in the gastrointestinal t ract. Rectal HPC is extremely rare; to the best of our knowledge, only two cases have been reported in the literature in Englis ... vessels around the tumor, which indicate the vascular origin of the tumor. The uncertainty of the rectal origin reflects the large exophytic nature of the tumor a nd it...

Ngày tải lên: 10/08/2014, 23:22

... (LIPC) is a lipolytic enzyme synthesized in hepatocytes playing a major role in HDL metabolism. It takes part in hydrolysis of triacylglycerides and phosphol- ipids of HDL 2 into antiatherogenic, ... polymorphisms are summarized in this additional file 1. Abbreviations: A: Arginin; C: Cytosin; G: Guanin; T: Thymin; HDL: high density lipoprotein; LDL: low density lipoprotein; VLD...

Ngày tải lên: 10/08/2014, 10:20

... a mutant trypsin with chymotryp- sin-like activity. It is very slow because the recognition sites for chymotrypsin are only outside of the interdomain loop in this basically trypsin-like structure ... sites of chymotrypsin. D-Chymotrypsinogen is a chimera constructed to contain a trypsinogen propeptide instead of the Cys1–Cys122-linked wild-type chymotryp- sinogen peptide. D-Chymo...

Ngày tải lên: 22/02/2014, 07:20

... amounts of sialylated Hex3 glycoforms were indicated. b Minor amounts of Hex2 and Hex3 glycoforms lacking acetyl groups or containing a second glycyl group were indicated. c Very minor amounts ... loci in the type b strain Eagan (RM153) [8] and in the index sequenced strain, Rd – (RM118) [9]. Gene functions have been identified t hat are responsible for most of the steps in th...

Ngày tải lên: 31/03/2014, 21:21

... proteins between the N and I domains. The N and I domains are not separable in the T4 RNase H protein as the N-domain forms part of the a/b structure respo nsible for fork bindi ng and half of the ... leading strand polymerase, allowing for the assembly and coordination of lagging strand synthesis. Once gp41 helicase is assembled onto the replication fork by gp59 prote...

Ngày tải lên: 11/08/2014, 21:21

... Residues that are involved only in CD4 binding are depicted in blue, residues involved in IgGb12 binding are depicted in yellow, residues that interact both with CD4 and IgGb12 are displayed in green ... that are involved only in CD4 binding are depicted in blue, residues involved in IgGb12 binding are depicted in yellow, residues that interact both with CD4...

Ngày tải lên: 13/08/2014, 05:21

... hypertension, and polycystic ovary syndrome. Though questions remain about the pathophysiology of treatment-emergent diabetes, guidelines are being formu- lated to aid clinicians in identifying ... Angiotensin Converting Enzyme CYP = Cytochrome P450 + Not all agents are appropriate for monotherapy. Inclusion in this table does not necessarily imply efficacy. * Currently FDA appro...

Ngày tải lên: 25/10/2012, 10:51