Hyperglycaemia in critically ill patients: marker or mediator of mortality? ppsx

... stratified according to their level of hyperglycaemia, and a clear correlation between level of hyperglycaemia and increased risk for mortality was identified (Figure 1). In the DIGAMI (Diabetes Insulin-Glucose ... between hyperglycaemia and in- hospital mortality was not uniform; hyperglycaemia was an independent risk factor only in patients without a history of diabetes i...

Ngày tải lên: 12/08/2014, 23:24

... above 6.1 mmol/l in 86% and almost Review Hyperglycaemia in critically ill patients: marker or mediator of mortality? Anouk M Corstjens 1 , Iwan CC van der Horst 2 , Jan G Zijlstra 3 , AB Johan Groeneveld 4 , ... value of hyperglycaemia, and of the effects of glucose control in different groups of critically ill patients, in order to evaluate the availab...

Ngày tải lên: 12/08/2014, 23:24

... in most studies. Methods of insulin administration Insulin was administered in different ways: subcutaneously, continuous intravenous infusion combined with intravenous bolus injections, or insulin ... followed by intravenous insulin if needed, resulted in glycaemic control in only two- thirds of ICU patients. Continuous insulin infusion Most study protocols used continuous intr...

Ngày tải lên: 12/08/2014, 23:21

... major determinant of mortality. Finally, Sofianou and colleagues [26], in a pro- spective cohort study examining the incidence, risk factors and pathogens of VAP, concluded that the occurrence of ... of stay in the ICU was found to be statistically significantly increased in patients with A. baumannii infection in three of five studies examining this outcome. The increase i...

Ngày tải lên: 12/08/2014, 23:23

... provided, either in the study by Forceville and colleagues or in any other published study of septic patients or in septic animal models. In contrast, inducing apoptosis of beneficial cell lines (such as intestinal ... levels of plasma selenium have been observed in critically ill patients and are associated with increased markers of oxidative stress, worse organ fai...

Ngày tải lên: 13/08/2014, 08:20

... Erythrocyte zinc protoporphyrin (ZPP). During erythro poiesis, Fe is normally incorporated into protoporphyrin IX to form heme. In iron defi ciency, zinc is substituted for iron, leading to the formation ... hepcidin, which is the master regulator of iron metabolism. Hepcidin binds to ferroportin, inducing its internalization and destruction, thus avoiding iron export. In ammation in...

Ngày tải lên: 14/08/2014, 07:21

... cystatin C to creatinine clearance (C Cr )Relationships of (a) serum creatinine and (b) serum cystatin C to creatinine clearance (C Cr ). Figure 2 The (a) inverse of serum creatinine (1/creatinine) ... (b) inverse of cystatin C (1/cystatin c) were plotted against creatinine clearance (C Cr ) for each of patient (P = 0.002 versus P < 0.001)The (a) inverse of serum creatinine (1/cr...

Ngày tải lên: 12/08/2014, 20:21

... systemic responses in which hypoxia inducible factor-1 is involved, all of which are of importance in preventing energy failure by rearranging more favorable fuel utilization and by increasing local oxygen ... in December 2004 for his presentation on lactate and mitochondria injury in an event organized by Instrumentation Laboratories S.p.a. There are no other financial or non-...

Ngày tải lên: 12/08/2014, 23:20

... number not for citation purposes) Vol 10 No 2 Research Arterial blood pressure monitoring in overweight critically ill patients: invasive or noninvasive? Ali Araghi, Joseph J Bander and Jorge A Guzman Division ... erroneous interpretations of blood pressure. Introduction Although the prevalence of critically ill, morbidly obese patients in the USA is not known, it has been...

Ngày tải lên: 12/08/2014, 23:23

... leading cause of all nosocomial bloodstream infections in the US, accounting for up to 11% of all infections [10]. As early as the 1980s, an increase in surgical yeast infec- ALI = acute lung injury; ... com- paring crude relative OR (crude OR SAP divided by crude OR SDD) and relative OR adjusted for the proportion of surgical patients (adjusted OR SAP divided by adjusted...

Ngày tải lên: 13/08/2014, 10:20