Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcome pptx
Báo cáo y học: " Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcome" pot
... a threshold effect with clear risk classes. Furthermore, early changes in protein C levels, in combination with baseline pro- tein C levels, predict outcome. Patients whose protein C levels fail ... patients and normal (>80%) patients who had a ≥ 10% decrease in protein C levels by day 1. Conclusion Baseline protein C levels were an independent predicto...
Ngày tải lên: 12/08/2014, 23:24
Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcome pptx
... changes in pro- tein C. Conclusion In summary, the current study confirmed that baseline protein C levels are an independent predictor of outcome in severe sepsis patients. Early changes in protein ... clear risk classes. Furthermore, early changes in protein C levels, in combination with baseline pro- tein C levels, predict outcome. Patients whose pr...
Ngày tải lên: 12/08/2014, 23:24
Báo cáo y học: "Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated)" pptx
... baseline PC levels and early changes in PC were prognostic of outcome. Change in PC levels on the first day after diagnosis of severe sepsis was highly correlated with outcome, with a decrease ... - APACHE, Acute Physiology and Chronic Health Evaluation; DrotAA, drotrecogin alfa (activated); ENHANCE, Extended Evaluation of Recombinant Activated Protein C; PROWESS, Recombin...
Ngày tải lên: 13/08/2014, 08:21
Báo cáo y học: " Randomized trial evaluating serial protein C levels in severe sepsis patients treated with variable doses of drotrecogin alfa (activated)" docx
... directional change in plasma levels predicts outcome. Crit Care 2006, 10:R92. 12. Brunkhorst F, Sakr Y, Hagel S, Reinhart K: Protein C concentrations correlate with organ dysfunction and predict outcome independent ... by an unadjusted two-sample t-test. † Change in protein C results analyzed with imputation. ‡ Percentage of protein C change from baseline...
Ngày tải lên: 14/08/2014, 07:21
Báo cáo y học: " Early lactate clearance is associated with biomarkers of inflammation, coagulation, apoptosis, organ dysfunction and mortality in severe sepsis and septic shock" docx
... the infecting pathogen may inhibit or induce apoptosis, involving both the extrinsic and intrinsic pathways, to enhance its damaging effects t o the host [53]. Caspase activation in apoptosisisanenergy-dependent ... American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative th...
Ngày tải lên: 11/08/2014, 08:22
Bóa cáo y học: "Use of an integrated clinical trial database to evaluate the effect of timing of drotrecogin alfa (activated) treatment in severe sepsis" ppt
... complica- tions and secondary nosocomial infections. Conclusion By combining records from several clinical studies of severe sepsis conducted by a common sponsor, the INDEPTH data- base permits an ... therapy, severe sepsis remains APACHE = Acute Physiology and Chronic Health Evaluation; DrotAA = drotrecogin alfa (activated); ENHANCE = Extended Evaluation of Recom- binant Human Activate...
Ngày tải lên: 12/08/2014, 23:23
Báo cáo y học: " Time course of plasma gelsolin concentrations during severe sepsis in critically ill surgical patients" pptx
... severe sepsis were enrolled upon admission to the ICU, using the criteria of the American College of Chest Physician/Society of Critical Care Medicine Consensus Conference Committee [19]. Exclusion ... isoform, and contains six homologous repeats termed gelsolin-like (G) domains [1-3]. Plasma gelso- lin is the principal circulating protein able to sever and scav- enge circulating filame...
Ngày tải lên: 13/08/2014, 11:22
Báo cáo y học: "Early drotrecogin alpha (activated) administration in severe sepsis is associated with lower mortality: a retrospective analysis of the Canadian ENHANCE cohort" ppsx
... finding in the cur- rent analysis that early changes in serum creatinine and plate- let count were independent predictors of mortality has direct clinical implications. In the rapidly changing ... score, baseline prothrombin time, number of organ failures at baseline, pre-infusion APACHE II score, baseline SOFA cardiovascular score, change in platelets, and change in creatinin...
Ngày tải lên: 13/08/2014, 16:20
Spatial Variation of Metal Concentrations in Watercourses of an Urban River Basin in Southeastern Brazil
... basin is composed of carbonate rocks, with several limestone mining and cement companies (CPRM, 1998). Anthropogenic inputs of zinc include manufacturing processes (production of iron, chemicals, ... features and is accordingly used for achieving specific objectives (Wuderlin et Address correspondence to Cristiano Christofaro, Email: christofaro@gmail.com Received July 10, 2009, Accepted...
Ngày tải lên: 05/09/2013, 10:15
báo cáo khoa học: "Severe sepsis caused by Aeromonas hydrophila in a patient using tocilizumab: a case report" pps
... tocilizumab in clinical trials [7,8]. Serious bacterial, viral or fungal infections can occur when using Figure 1 CT scan showing cholelithiasis (white arrow), choledocholithiasis and dilated common ... of which were suscep- tible to cefoperazone-sulbactam. A. hydrophila was resistant to penicillin, ampicillin, ampicillin-sulbactam, and first- and second-gen eration cephalosporins, and susc...
Ngày tải lên: 10/08/2014, 23:20