Báo cáo y học: "Recently published papers: Pandemic flu, the latest ARDS trials, raising legs and other stories" docx

... at day 7. There were no significant differences in any of the other secondary outcomes although, notably, the mortality rates in both groups were high (58% and 66%, respectively) reflecting the ... contrast, the ARDSnet trial investigating the safety and efficacy of moderate-dose corticosteroids in persistent ARDS [6] fails, in my opinion, to answer either question reliably...

Ngày tải lên: 12/08/2014, 23:24

... reported by Lim and coworkers [3,4]. The modified American Thoracic Society guidelines were superior to the other tools in predicting the severity of community-acquired pneumonia, as judged by need ... two treatment groups. The study was pragmatically planned, dictating only the fluid resuscitation of the patients, leaving clinicians free to manage all other aspects of the...

Ngày tải lên: 12/08/2014, 20:20

... recent paper on the effects of methylprednisolone in unresolving acute respiratory distress syndrome [10], and may account for a therapeutic modality by which high-dose steroid therapy works. It ... study, but it positively contributes towards a rationale for the use of steroids in management of the inflammatory response. Thromboembolic disease is a frequent cause of morbidity and m...

Ngày tải lên: 12/08/2014, 18:21

... of mortality risk in the critically ill. This was no doubt triggered by the Acute Physiology and Chronic Health Evaluation (APACHE) III as well as the study reported by McCluskey and colleagues ... recent study reported by Yap and coworkers [7]. They retrospectively studied more than 1000 patients over an 18-month period, their hypothesis being that serum hypoalbuminaemia may be p...

Ngày tải lên: 12/08/2014, 18:21

... reported by Weber and colleagues [22]. Sadly, adoption of this technique, in the UK at least, awaits the deliberation of the government and judiciary. Finally, if you have been seduced by the attractive ... safe and inexpensive, and that there is now good evidence to support its routine use in the severest cases, it only remains for the optimal dose and duration of thera...

Ngày tải lên: 12/08/2014, 19:21

... surgery, trauma and sepsis patients. Their findings confirmed further that when therapy is aimed at improving oxygen delivery (especially in the severely ill, in whom control group mortality was ... further implicating involvement of the neuroendocrine system in sepsis, have they found a highly predictive marker? Time and further investigation will surely tell. Are we drawing too many...

Ngày tải lên: 12/08/2014, 19:21

... and ICU days and consequently outcome, and that a sedation protocol including daily cessation of sedative agents is of benefit. However, is any one agent or group of agents superior to the others? ... sedation, haemodynamic stability and time to extubation, among others. Unsurprisingly, the studies showed wide clinical heterogeneity and this precluded formal statistical analysis...

Ngày tải lên: 12/08/2014, 19:22

... adopted with the same enthusiasm as that of the balloon directed pulmonary artery catheter in the early 1980s. There is some good news for the pulmonary artery catheter enthusiasts – there was no ... and the patients were all aged over 60 years and were at least American Society of Anesthesiologists class III. The conclusions were that there was no benefit to therapy directed...

Ngày tải lên: 12/08/2014, 19:22

... respiratory syndrome) epidemic and a war in Iraq beamed live into our daily lives. The weekly medical journals have covered these events and contributed to the debates surrounding them. These events ... study undoubtedly provides further evidence to support the enormous ongoing efforts to tackle this phenomenon. Obesity Against the background of the global epidemic of obesity,...

Ngày tải lên: 12/08/2014, 19:22

... 282 ARDS = acute respiratory distress syndrome; DHEA(S) = dehydroepiandrosterone (sulphate); NO = nitric oxide. Critical Care August 2003 Vol 7 No 4 Bayley and Venn The search for the marker ... insufficiency extends to androgens, that DHEA and DHEAS changes do not parallel each other, and that DHEAS levels may even predict survival in severe sepsis, which APACHE (Acute Physiolog...

Ngày tải lên: 12/08/2014, 19:22