Báo cáo y học: "Arginine vasopressin versus norepinephrine: will the stronger one win the race" pot

... sepsis. Finally, although redistribution of blood flow away from non- vital organs (e.g. the skin) to vital organs represents one of the primary therapeutic aims of vasopressor therapy (especially in ... vasodilatory shock remains unresolved. The fact that AVP infusion may impair gut mucosal microcirculation [6] and skin perfusion [7] suggests that the stronger one may not neces...

Ngày tải lên: 12/08/2014, 23:24

... purposes) finding may be explained by the less severe septic shock at the time of treatment initiation (drop in MAP of 10% in the present study vs. 30% in the latter study) and is in line with the results ... Notably, only 36% of the patients treated with AVP were supplemented with norepi- nephrine [12]. Reviewing the current literature on this topic together with the work of...

Ngày tải lên: 13/08/2014, 18:22

... inflammatory parameters and duration of ventilatory support, and mortality as a secondary outcome. The a priori hypothesis is that synergistic action of combination therapy will accelerate the resolution ... therapy over monotherapy, the use of empirical combination therapy remains probably relevant in patients with potentially multire- sistant strains, as recommended by Chastre [30]....

Ngày tải lên: 12/08/2014, 23:23

... adaptive evolution to the lymph nodes and the eyes, respectively, considering their extreme conservation among the corresponding strains. On the other hand, these genes may be responsible for ... evaluated the homogeneity of substitution patterns between sequences by calculating the Monte Carlo test-based Disparity Index per site [55]. This gives the probability of rejecting th...

Ngày tải lên: 14/08/2014, 21:20

... of AVP therapy of cardio-respiratory failure; no ischemic lesions secondary to AVP therapy. A congenital cardiac malformation and cardiomyopathy were ruled out by autopsy 5 Twin II: ... of AVP therapy of cardio-respiratory failure; no ischemic lesions secondary to AVP therapy. A congenital cardiac malformation and cardiomyopathy were ruled out by autopsy 6 Twin I: 24 ... hyp...

Ngày tải lên: 12/08/2014, 23:23

... period (P = 0.047). There was no significant overall group difference in the other variables of systemic hemodynamics. New-onset tachyarrhythmias The incidence of new-onset tachyarrhythmias (i.e atrial ... become evident that the efficacy of hemodynamic optimization by fluids and vasopressor agents critically depends on the urgency of therapy [1-4]. The recent Vasopressin and Sept...

Ngày tải lên: 13/08/2014, 18:22

... Glu58 as the general base during the first step of the reaction. The hydrolysis of the cyclic derivative is performed by the same groups, but their roles are reversed [23]. In a-sarcin the same ... the a-fragment result- ing from the specific ribonucleolytic activity of these fungal ribotoxins against ribosomes. Forty nanograms of the wild- type protein was enough to complet...

Ngày tải lên: 31/03/2014, 23:20

... significantly associated with lupus disease activity, as assessed by the SLEDAI-2K (Systemic Lupus Erythematosus Disease Activity Index 2000) or C3 levels. The chemokine score showed a slightly greater degree ... nephritis, although this effect was blunted in the patients treated with at least 30 mg of prednisone daily. Nonetheless, the data suggest that the chemokine score might be...

Ngày tải lên: 09/08/2014, 01:22

... patients, and healthy donors and that support the potential utility of measuring chemokine transcripts in peripheral blood as an indicator of disease activity. Their study builds on a growing literature ... literature that has used microarray, real-time polymerase chain reaction, or functional assays of IFN-α activity to quantify activation of the IFN pathway [5-7]. The measurement of s...

Ngày tải lên: 09/08/2014, 13:22

... participated in the design, coordinated the study, performed the statistical analysis. RC: participated in the design of the study and the statistical analysis. AT: helped to draft the manuscript. ... in the design of the study. AA: participated in the design of the study and the statistical analysis. GG: helped to draft the manuscript. SM: performed coronary angiogr...

Ngày tải lên: 10/08/2014, 09:22