Bóa cáo y học: "Use of an integrated clinical trial database to evaluate the effect of timing of drotrecogin alfa (activated) treatment in severe sepsis" ppt
Bóa cáo y học: "Use of an integrated clinical trial database to evaluate the effect of timing of drotrecogin alfa (activated) treatment in severe sepsis" ppt
... purposes) the leading cause of death in the intensive care unit, and its incidence is increasing [1,2]. Among the many compounds evaluated for the treatment of severe sepsis [3], only drotrecogin alfa ... logistic and Cox regression analysis of DrotAA treatment effect by time to treatmentLandmark logistic and Cox regression analysis of DrotAA treatment effec...
Ngày tải lên: 12/08/2014, 23:23
Báo cáo khoa học: "Timing of drotrecogin alfa (activated) treatment in severe sepsis" pps
... frequently involved pathogen in these pneumonia patients (seven of 12 cases, 58%). Notably, and in contrast to the analysis of the INDEPTH data, hospital mortality rates were comparable Letter Timing ... outcome of severe sepsis was recently evaluated, using the integrated clinical trial database INDEPTH. The evaluation demonstrated an association between ear...
Ngày tải lên: 13/08/2014, 02:24
Báo cáo y học: "FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions" pot
... to other resources, we first compare the FANTOM4 instance of EEDB and the data contained within to similar genomic resources, and then compare the EEDB system to other pre-existing systems. The ... descriptions of the data collected and analyses used for each of the edge types contained within EdgeExpressDB, we refer the reader to the FANTOM4 main paper [1]; howe...
Ngày tải lên: 14/08/2014, 21:20
Bóa cáo y học: "Does productivity influence priority setting? A case study from the field of CVD prevention" ppsx
... that are financed today. We use a deterministic model to compute the effect of an intervention. The starting point is a cohort of CVD-free individuals. Every year the cohort is exposed to the risk of suffering ... neces- sary to analyse the incremental effects and costs of each. The health gains of any particular intervention depend, among other things, on the...
Ngày tải lên: 13/08/2014, 11:22
Báo cáo khoa học: Investigations into the ability of an oblique a-helical template to provide the basis for design of an antimicrobial anionic amphiphilic peptide pot
... instability may contribute to the susceptibility of E. coli model membranes to the action of AP1. An important determinant of the susceptibility of membranes to a-AMPs is the packing characteristics of ... consistent with the peptide penetrat- ing deeply into the membranes hydrophobic core. To investigate further the mechanism of bacterial membrane interact...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo y học: "Using single nucleotide polymorphisms as a means to understanding the pathophysiology of asthma" pps
... [145]. Confirmation of these findings could mark the beginning of the clinical use of genotyping at an individual level as an adjunct to phar- macotherapy for asthma and many other disorders. Statistical ... understanding of the pathophysiology of this disorder, but they also offer significant challenges. Despite much progress in defining the genetic basis of ast...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: "Early drotrecogin alpha (activated) administration in severe sepsis is associated with lower mortality: a retrospective analysis of the Canadian ENHANCE cohort" ppsx
... Trzaskoma B, Sundin D: Use of an integrated clinical trial database to eval- uate the effect of timing of drotrecogin alfa (activated) treat- ment in severe sepsis. Crit Care 2006, 10:R74. 28. Kanji S, ... 'stable', and may wait a significant amount of time in order to determine a 'clear' increased or increasing risk of death. On...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "yrGATE: a web-based gene-structure annotation tool for the identification and dissemination of eukaryotic genes" pdf
... by the annotator. Then, the annotator creates a new annotation using the Annotation Tool and decides to submit the annotation to the community. This newly submitted annotation is listed in the ... for specifying custom exons, allowing thorough analysis and quick annotation of loci. Annotators access the tool over the web, where they create an annotation, decide to...
Ngày tải lên: 14/08/2014, 16:21
Báo cáo y học: "Positive end-expiratory pressure at minimal respiratory elastance represents the best compromise between mechanical stress and lung aeration in oleic acid induced lung injury" pps
... CT morphological analysis to separate the effects of reduction in the amount of aeration from the concomitant increase in the amount of tissue and liquid observed with PEEP reduction. The increase in the ... At the end of the protocol, the ani- mals were killed using an intravenous injection of potassium chloride while they were deeply sedated. Computed t...
Ngày tải lên: 13/08/2014, 08:20