Báo cáo y học: "Small volume of hypertonic saline as the initial fluid replacement in experimental hypodynamic sepsis" pptx
... immediately after fluid infusion in both groups (Table 1). Hypertonic saline infu- sion induced a sustained increase in serum sodium levels (Table 1). Discussion Using an intravenous injection of live ... meas- uring protocol was initiated and the infusion of LR was discontinued. A large gastric polyethylene tube was orally introduced and placed in the stomach to allow gas...
Ngày tải lên: 12/08/2014, 23:23
... pericardial fluid. An adenosine deaminase assay, which has been used to identify tuberculosis, was unin- terpretable due to the am ount of blood in the fluid [9]. Initially, we discharged the patient ... uncommon in North America [5]. Our initial high suspicion for tuberculous pericarditis was based on her history, the bloody fluid, the mediastinal adenopathy, and the...
Ngày tải lên: 11/08/2014, 03:21
... pericardial fluid. An adenosine deaminase assay, which has been used to identify tuberculosis, was unin- terpretable due to the am ount of blood in the fluid [9]. Initially, we discharged the patient ... uncommon in North America [5]. Our initial high suspicion for tuberculous pericarditis was based on her history, the bloody fluid, the mediastinal adenopathy, and the...
Ngày tải lên: 11/08/2014, 07:20
Báo cáo Y học: Amphipathic property of free thiol group contributes to an increase in the catalytic efficiency of carboxypeptidase Y pot
... maintain hydrophobicity and Gly, Ser, Asp and His mutants to provide hydrophilicity. The catalytic roles of Cys341 in carboxypeptidase Y are examined by comparing the kinetic parameters of the ... because of elimination of the bulky SH group. It has been suggested that eliminating steric constraints present in the S1 subsite of the wild-type carboxypeptidase Y wo...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Domain V of m-calpain shows the potential to form an oblique-orientated a-helix, which may modulate the enzyme’s activity via interactions with anionic lipid potx
... progressive increase in hydrophobicity in moving from the N-terminus to the C-terminus (Fig. 2), suggesting the ability to form an a-helix with an asymmetric distribution of hydrophobicty along the a-helical ... °Cand52°C, respectively, and accompanied in each case by a minor increase in membrane fluidity (Fig. 6A,B). In contrast, the presence of VP1 led to a large decr...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Identification of novel membrane proteins by searching for patterns in hydropathy profiles potx
... was designed for the acetylcholine (ACh) and glycine receptors of the cys-loop receptor superfamily. The key feature was a closely spaced triplet of hydropathy peaks bracketed by deep valleys. ... sensi- tivity, as it was able to detect 100% of known GlyR and AChR across a range of species. The accuracy and sensitivity of the search strategy were tested by applying it to...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: Proteolytic action of duodenase is required to induce DNA synthesis in pulmonary artery fibroblasts A role for phosphoinositide 3-kinase pot
... labelling (Fig. 1g). Duodenase induces DNA synthesis in pulmonary artery fibroblasts The effect of duodenase on DNA synthesis w as assessed using [ 3 H]thymidine incorporation in bovine primary pul- monary ... and release of their proteinases may therefore play a central role in the initiation of a p roliferative response following injury or in ammation within the lung. T...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: Identification of an element within the promoter of human selenoprotein P responsive to transforming growth factor-b ppt
... multifocal in ammatory lesions as the main phenotype [29,30]. The Smad family of proteins has been characterized as mediators of TGF-b signalling in recent years [14,23]. After binding of TGF-b 1 to ... a decrease in SeP. As TGF-b 1 plays an important role in regulation of in ammatory processes as well as in wound healing, an involvement of the signalling p...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: "Decreased levels of soluble amyloid β-protein precursor and β-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus" ppsx
... present at increased levels in the CSF [30], and has also been detected in senile plaques. The aim of the present study was to measure the levels of brain-specific proteins directly or indirectly related ... system (CNS) frequently occur in patients with systemic lupus erythematosus (SLE). These symptoms are extremely diverse, including a state of dementia. The aim of...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Direct interaction of immunoglobulins with synovial fibroblasts: a missing link in the pathogenesis of rheumatoid arthritis" potx
... article by Terry Smith and William Cruikshank in the Journal of Immunology provides fascinating yet unexpected insights into how autoantibodies contribute to the maintenance of inflammatory disease ... directly to the pathogenesis of synovial inflammation and joint destruction has seen a ‘revival’ over the last couple of years [6,7]. This is mainly due to the observation t...
Ngày tải lên: 09/08/2014, 06:22