Báo cáo y học: "Mutagenesis analysis of the zinc-finger antiviral protein" ppt

... impor- tant for the antiviral activity of ZAP [7,9,10]. The results are summarized in table 1. Figure 2 The activity of the ZAP mutants to bind the target RNA. The lysates of Rat2 cells expressing the indicated ... to understand how the activity of these mutants was affected, they were further analyzed for their interaction with the target RNA, the exosome, and...

Ngày tải lên: 12/08/2014, 23:23

... activity of the mutant m-126 Luc even below that of the wild-type p-126 Luc. Analysis of the binding affinity of the putative FXRE site for the orphan nuclear receptor FXR To characterize the FXRE ... Thus, we present the nucleotide sequence, as well as a systematic structural and functional analysis of the 5¢ flanking region of the Bsep gene. The 5¢ deletion...

Ngày tải lên: 17/03/2014, 23:20

... 25. Methylation analysis of dephosphory- lated O S-1 showed significantly increasing amounts of terminal Glc and 2-substituted Hep, thereby indicating phosphorylation of these residues i n the native ... protons of AnKdo-ol were observed in the DQF-COSY and TOCSY spectra of OS-1 in the region d 2.20–1.66. A s observed earlier [11], several anhydro-forms of K do are formed d...

Ngày tải lên: 31/03/2014, 21:21

... indicating the importance of antigen presenta- tion in the induction of autoimmunity. This finding clearly could be confirmed in our study. With the exception of haplotype 4, the frequencies of all other PADI4 ... http://www.kursus.kvl.dk/shares/vetgen/_Popgen/ genetik/applets/kitest.htm). Results Distribution of PADI4 haplotype combinations The frequencies of the PADI...

Ngày tải lên: 09/08/2014, 07:20

... requirements. Conclusion Notwithstanding these limitations, this study provides the first stringent evaluation of one of the self-report scales of DSH using Rasch analysis. Further, such evaluations of the BMC Psychiatry 2009, ... population may not be indicative of psycho- pathology but a score of 11 may be suggestive of some psychopathology. The scale authors in their...

Ngày tải lên: 11/08/2014, 17:20

... characterization of many of these suspect viruses, the etiology of the poultry enteric disease syndromes remains elusive, and many enteric viruses can be detected in otherwise healthy turkey and chicken ... in the same units as those of the evolutionary distances used to infer the phylogenetic tree. The evolutionary distances were computed using the Poisson correction me...

Ngày tải lên: 12/08/2014, 02:20

... were sequenced by means of a Prism ready reaction Dyedeoxy terminator cycle sequen- cing kit (Applied Biosystems, Foster, USA). Data analysis Thesequencedatawerecheckedforanyhomologyin BLAST (N ... are HLA-restricted specific cytotoxic T lymphocytes (CTLs). As EBV can switch dir ectly from the latent state into the lytic cycle without any expres- sion of further latent proteins [20]...

Ngày tải lên: 12/08/2014, 02:20

... center of gravity. Computer Systems Analysis of the Hypothesis The hypothesis was examined through a systems analysis approach using a derivative of a well-established computer model of circulatory ... women due to their inher- ent lower center of gravity and proportionately larger mass in the lower extremities. Examining the theoretical consistency of the hypothesis...

Ngày tải lên: 13/08/2014, 16:20

... consequently, it may then be beneficial to isolate further progeny and increase the marker density to improve the resolution of the map in the specific area of the genome. Under these circumstances other ... are unlikely to signify regions of true segre- gation distortion. Therefore, the previously reported region of chromosome 1 remains the only region of the STIB 3...

Ngày tải lên: 14/08/2014, 20:22

... by the fact that most genes are not statistically signif- icantly different among lines and that inclusion of these genes in the analysis may obscure an effect. Thus, we repeated the analysis ... result may reflect the fact that, in the female analysis, there is an excess of male-biased genes in the lowly expressed class and male-biased genes tend to have particularly low...

Ngày tải lên: 14/08/2014, 20:22