Báo cáo y học: " Coupling of receptor interference and a hostdependent post-binding entry deficiency in a gammaretroviral envelope protein" doc

... containing envelopes from SL3-2 or its mutants we find that the same amino acid mutations can dramatically alter the interference profile of this polytropic ENV, suggesting that the same amino acid ... 1990, 64:6176-83. 33. Bahrami S, Jespersen T, Pedersen FS, Duch M: Mutational library analysis of selected amino acids in the receptor binding domain of envelope of Akv murine l...

Ngày tải lên: 12/08/2014, 23:23

... cells/plate. XC cells produce plaques containing syncytia in response to focal areas of virus infected cells. Plates were fixed and stained 3 days later and examined for plaques of syncytia. Syncytium ... pseudotype experiments. YY did the unintegrated DNA analysis. YY and TW did the Western analysis and virus infections. CK did the cytopathicity tests and drafted the manuscri...

Ngày tải lên: 13/08/2014, 06:20

... prepared the manuscript. SK, SA, MW and CB participated in the collection of clinical data and the recruitment of patients into the study. UW and HH partici- pated in the design of the study, statistical ... Germans. The genotype and allele frequencies in the healthy controls were comparable to those reported previously in populations from the US, Canada and Spain, an...

Ngày tải lên: 09/08/2014, 08:22

... criteria of a national good practice guideline [26,27]. According to the Good Practice of Secondary Data Analysis, a national guideline for the use of administrative databases, no approval of an ... LP: Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute...

Ngày tải lên: 11/08/2014, 16:21

... according to respiratory varia- tion in systolic arterial pressure. A similar result was reported by Kiefer and colleagues and by Akinci and colleagues Table 1 Baseline characteristics of the patients Patient ... median (range) age of 63.5 years (23–86), and an Acute Physiology and Chronic Health Evaluation II score of 14 (7–20) at admis- sion to the intensive care unit. O...

Ngày tải lên: 12/08/2014, 20:20

... subtypes were determined in cell-free assays. Efficiency of (-) ssDNA synthesis and initiation by subtype C RTs was measured using gel-based assays with HIV-1 PBS RNA template and tRNA3 Lys as ... percentage of specific activity of subtype B WT RT with the percentage standard deviation of the duplicate samples also indicated. Incorporation efficiency of TFV-DP in cell-free...

Ngày tải lên: 13/08/2014, 05:21

... pulmonary damage separating responders from nonresponders may be an explanation for the varying responses to INO. Besides, a limitation may include the intra- variability and intervariability of ... performed the statistical analysis and interpretation of data, edited the manuscript and acquired funding. GD-D was involved with the biochemical analysis (immunoassays) and with edi...

Ngày tải lên: 13/08/2014, 11:23

... expression and regulation by dasatinib analyzed at mRNA and protein levelsFigure 3 uPA gene expression and regulation by dasatinib analyzed at mRNA and protein levels. (a) Differential baseline expression ... Identification of these preclinical candidate markers and further validation of them in early clinical trials would facilitate patient stratifi- cation in registration...

Ngày tải lên: 14/08/2014, 08:20

... 1):235-241. 11. Patel KP, Sandy JD, Akeda K, Miyamoto K, Chujo T, An HS, Mas- uda K: Aggrecanases and aggrecanase-generated fragments in the human intervertebral disc at early and advanced stages of disc ... 7:R732-R745. 14. Patwari P, Gao G, Lee JH, Grodzinsky AJ, Sandy JD: Analysis of ADAMTS4 and MT4-MMP indicates that both are involved in aggrecanolysis in interleukin-1-tre...

Ngày tải lên: 09/08/2014, 14:22

... Percent of pravastatin and hemoglobin release from loaded erythrocytes in PBS and plasma. Data were tested by one-way analysis of variance and represented as mean ± SD. Three samples in each group ... of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia  Corresponding author: Fars K. Alanazi, Kayyali Chair for Pharmaceutic...

Ngày tải lên: 25/10/2012, 11:10