Báo cáo y học: " Cell-specific targeting of lentiviral vectors mediated by fusion proteins derived from Sindbis virus, vesicular " doc

... Access Cell-specific targeting of lentiviral vectors mediated by fusion proteins derived from Sindbis virus, vesicular stomatitis virus, or avian sarcoma/ leukosis virus Xian-Yang Zhang 1,2 , Robert ... al.: Cell-specific targeting of lentiviral vectors mediated by fusion proteins derived from Sindbis virus, vesicular stomatitis virus...

Ngày tải lên: 12/08/2014, 23:22

... epitope in the Ago proteins by virtue of the high degree of sequence homology (approximately 80% identity) exhibited between the Ago proteins [13]. Regardless of the type of interaction that ... Biology, University of Calgary, 3330 Hospital Drive N.W., Calgary, AB, T2N 4N1, Canada 3 Division of Rheumatology and Clinical Immunology, Department of Medicine, and Department o...

Ngày tải lên: 09/08/2014, 08:22

... distribution of c-myc fusion proteins was detected by anti-c-myc-FITC antibody (green color) and mitochondria were labeled by Mito Tracker Red (red color). Only merged images are shown (colocalization of ... mitochondrial targeting of this protein (data not shown). Establishing the human disease mechanism of the early- onset hypertrophic cardiomyopathy and encephalopath The...

Ngày tải lên: 10/08/2014, 05:21

... saline; PE: phycoerythrin; PE-Cy7: phycoerythrin-cyanin 7; PerCP: peridin chlorophyll protein; Siglec-2: Sialic acid-binding Ig-like lectin 2; SLE: systemic lupus erythematosus; SyK: spleen tyrosine ... improvement in moderately and severely affected body systems in patients with systemic lupus erythematosus (sle) by epratuzumab: results from emblem™, a phase iib study. EULAR Meeting 2010...

Ngày tải lên: 12/08/2014, 15:21

... variants produced by p26-ND60 and p26-alpha were pr esent but recognized poorly by antip26 antibody. To determine if recognition of p26-ND60 and p26-alpha encoded polypeptides by antibody to p26 was ... H.S., Han, Y. & Fung, B.K K. (2000) Subunit e xchange of small h eat sho ck proteins. Analysis of olig- omer formation of aA-crystallin and Hsp27 by fluorescence res- onan...

Ngày tải lên: 22/02/2014, 04:20

... Germany; 4 Department of Medicine, Section Pathophysiology, Johannes Gutenberg University of Mainz, Germany; 5 Department of Biochemistry, Christian Albrechts University of Kiel, Germany Ciliary neurotrophic ... Blot analysis Proteins from cell lysates of transfected BAF/3 or PC12 cells were separated by SDS/PAGE and transferred onto poly(vinylidine fluoride) membranes by ele...

Ngày tải lên: 22/02/2014, 07:20

... activity of PpTGase might be similar to that by which they inhibit the enzymatic activity of TGase 4. Hydrolysing activity of GTP was also found in the purified PpTGase protein as in the case of TGase ... enzymatic activity was apparently decreased by the addition of 100–500 l M GTP. In the presence of 1 m M Ca 2+ , an inhibitory effect was observed only at a higher level of...

Ngày tải lên: 17/03/2014, 23:20

... paired membranes If analysis of crystalline arrays of paired membranes was focussed on the superposition of both layers, it became clear that the interaction of the rows of PSII complexes of adjacent layers was ... center of the paired membranes was observed in other crystals of the 328-type. Another aspect of the lateral freedom in the interaction of the two layers is dem...

Ngày tải lên: 24/03/2014, 04:21

... developing embryo by antagonizing Ang-1- induced autophosphorylation of Tie2 [6]. Transgenic mouse models of Tie2/Ang-1 result in embryonic lethality due to absence of remodeling and sprouting of blood vessels ... methods, the estimated amount of the gene of interest was normal- ized by the amount of glyceraldehyde-3-phosphate dehy- drogenase to compensate for variations in...

Ngày tải lên: 09/08/2014, 03:24

... inflammatory chemokine CXCL10, PBMC from patients with RA were tested with the use of a transmigration assay (Fig. 11). A cytometric analysis of the migrated cells revealed that both fractions of memory ... manuscript. Acknowledgements The work was supported by the SFB 421 and by the Network of Com- petence, Rheumatology (BMBF grant C2.2 to CB). The DRFZ is sup- ported by the...

Ngày tải lên: 09/08/2014, 06:23