Báo cáo y học: "Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue" docx

... Access Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue Michael Schindler 1* , Devi Rajan 2,3 , Carina Banning 1 , ... this article as: Schindler et al.: Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in...

Ngày tải lên: 12/08/2014, 23:22

... Burny, A. (1993) A calcium/calmodulin-binding serine/ threonine protein kinase homologs to the mammalian type II calcium/calmodulin- dependent protein kinase is expressed in plant cells. Plant Physiol. 101, ... CBF gene family is composed of three genes encoding AP2 domain-containing proteins whose expression is regulated by low temperature but not by abscisic acid or dehydra...

Ngày tải lên: 18/03/2014, 01:20

... regulation of cytokine induction by adenoviral gene transfer of IκBα into human macrophages: lipopolysaccha- ride-induced, but not zymosan-induced, proinflammatory cytokines are inhibited, but IL-10 is ... pattern of utilization of NFκB for the T-cell con- tact -dependent induction of CC and CXC chemokines in monocytes is surprising and indicates that chemokine gene...

Ngày tải lên: 09/08/2014, 08:23

... phosphate pathway Glycolysis Amino acid metabolism: all 20 amino acids Fatty acid metabolism: beta oxidation, lipid synthesis Purine metabolism Pyrimidine metabolism Intermediary metabolism Redox ... μM. Owing to the low inhibitory activity of the compound, the possibility of drug-drug interactions is very small. Even for CYP3A4, the major human CYP isoenzyme in the gut and liver...

Ngày tải lên: 09/08/2014, 22:24

... cycle of CAG regimen (cytarabine 30 mg/day for 14 days, aclarubicin 10 mg/day on days 1 - 8, and granulocyte colony-stimulating factor 300 μg/day on days 1 - 14). Imatinib was discontinued ... The cytoplasm of promegakaryocytes was basophilic and might show distinct pseudopod formation (Figure 1b). Immunohistochemistry staining (Leukocyte Phenotyping Kit, Sun BioTech, China) of...

Ngày tải lên: 10/08/2014, 21:23

... Apparently obtaining good excision margins is the most important predictor of local recurrences as it is for women. With a case report of only one patient, it is impossible to make any statement ... final version of the manuscript. Consent Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the w...

Ngày tải lên: 11/08/2014, 23:21

... inhibi- tion of the degradation of CD4 by Vpu occurred follow- ing the substitution of four lysines to arginines in CD4’s cytosolic domain, suggesting ubiquitination as a mechanism. We therefore ... more accessory proteins of HIV-1 play a key role in the observed decrease in GaLV TM levels. Interestingly, despite the lack of effect of R8.91 on intracellular GaLV TM levels,...

Ngày tải lên: 12/08/2014, 23:22

... phosphory- lation site for Akt (protein kinase B), is an alternative way to increase its enzyme activity [21], it is possible that Akt signaling may be involved in PKA -dependent nNOS phos- phorylation ... enhancement of BRR response by ADM in NTS is composed sequentiall y of cAMP/PKA and nNOS/PKG pathways. These findings may provide a new insight for our understanding o...

Ngày tải lên: 10/08/2014, 05:21

... were not involved in the DSMB's data analysis. The study was not terminated because of the finding of increased hospital mortality in patients treated by DIS. Censoring Thirty-six patients ... modifications of the initial strategy [8]. In the recently published Awakening and Breathing Con- ABC = Awakening and Breathing Controlled; ANOVA = analysis of variance; APACHE =...

Ngày tải lên: 25/10/2012, 10:35

... by the vaccination ineffective. Therefore, mutations may play a key role in the difficulties of managing hepatitis B infection. Hence, further research and understanding in this sector may ... sector may bring exciting new information and better understanding of the natural history of HBV and supplement our existing armamentarium to combat this persistent worldwide prevalent dise...

Ngày tải lên: 02/11/2012, 11:17