Báo cáo y học: "Inhibition of HIV-1 integrase nuclear import

Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt

... phosphorylation of Ó FEBS 2002 NAMI-A aﬀects c-myc gene expression and MEK/ERK phosphorylation (Eur. J. Biochem. 269) 5869 Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A ... counteracted, and ultimately abolished, the increase in c-myc gene expression elicited by PMA in serum-free cells. These results sug...

Ngày tải lên : 21/02/2014, 01:21

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Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot

... splicing inhibition by tetracycline is n egligible (Fig. 2). The sixfold stron ger splicing inhibition by Cl-tetracycline may be explained by the a dditional s ize and hydrophobicity introduced by the substitution, ... [31]. RESULTS Erythromycin, Cl-tetracycline and streptomycin inhibit nuclear splicing in vitro The effects of eight different antibiotics (the amino...

Ngày tải lên : 21/02/2014, 15:20

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Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc

... suggest that the inhibition of HA production was not caused by direct inhibition of HAS activity. Effect of MU on HAS activity in FM100 cells treated with MU The activity of the HAS in FM100 cells ... n-dodecyl-b- D -maltoside; GlcNAc, N-acetylglucosamine; GlcUA, glucuronic acid; HA, hyaluronan (hyaluronic acid); HABP, hyaluronan binding protein; HAS (Has), hyaluron...

Ngày tải lên : 08/03/2014, 09:20

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Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot

... into contact in the absence of ATP, curcumin is then able to bind to the ATPase (possibly at the hinge region) locking the two domains together and therefore precluding ATP binding (i.e. inhibiting ... point is the mean ^ SD of three determinations. q FEBS 2001 Inhibition of the Ca 2ỵ -ATPase by curcumin (Eur. J. Biochem. 268) 6323 Inhibition of the...

Ngày tải lên : 08/03/2014, 23:20

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Báo cáo Y học: Modulation of inositol 1,4,5-triphosphate concentration by prolyl endopeptidase inhibition ppt

... Kerenyi, T.D. (1971) Leucylglycinamide released from oxytocin by human uterine enzyme. Science 173, 827–829. 35. Shinoda, M., Miyazaki, A. & Toide, K. (1999) Eﬀect of a novel prolyl endopeptidase ... 0.0005). 5816 I. Schulz et al.(Eur. J. Biochem. 269) Ó FEBS 2002 Modulation of inositol 1,4,5-triphosphate concentration by prolyl endopeptidase inhibition Ingo Sc...

Ngày tải lên : 31/03/2014, 08:20

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Báo cáo Y học: Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues pot

... transduction in macrophages by glycosylphosphatidylinositols of Plasmodium, Trypanosoma, and Leishmania: activation of protein tyrosine kinases and protein kinase C by inositolglycan and diacylglycerol moieties. ... to study GPtdIns biosynthesis in a variety of cell-types and organisms. In all systems investigated so far, mannosamine was able to inhibit GPtdIns biosynthes...

Ngày tải lên : 31/03/2014, 23:20

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Báo cáo Y học: Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites ppt

... 2002 Inhibition of SERCA Ca 2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca 2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca 2+ -binding ... Ca 2+ binding and phosphoryl transfer and postulate that the drug binds to and interferes with the Ca 2+ entry...

Ngày tải lên : 31/03/2014, 23:20

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Báo cáo y học: "Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis" potx

... pathogenesis of RA. The principal plasma inhibitor of thrombin is antithrombin, a single-chain 51 kDa glycoprotein that is synthesized in liver. The inhibitory activity of antithrombin on thrombin is ... presence of HA, supporting the notion that HA could compete with heparin for the heparin-binding region of antithrombin. Remarkably, HA affected the inhibition b...

Ngày tải lên : 09/08/2014, 06:22

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Báo cáo y học: "Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice" docx

... of inhibitors of uptake on the intracellular processing of type II collagen (CII) by dendritic cellsThe effect of inhibitors of uptake on the intracellular processing of type II collagen (CII) ... cells by inhibition of antigen uptake in HLA-DR1- transgenic mice in vitro and in vivo. Electron microscopy, confocal microscopy, subcellular fractionation...

Ngày tải lên : 09/08/2014, 08:22

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Báo cáo y học: " Compression of the radial nerve at the elbow by a ganglion: two case reports" pot

... the metacarpophalangeal joints at the fingers and the interphalangeal joint at the thumb had decreased. Sonography and magnetic resonance imaging of the elbow revealed a cystic lesion located at the ... joint past the proximal edge of the supinator muscle [1,2]. Compressive neuro- pathies of the radial nerve in the radial tunnel can occur anywhere alo...

Ngày tải lên : 11/08/2014, 17:21

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Báo cáo y học: "Inhibition of IFN-γ-dependent antiviral airway epithelial defense by cigarette smoke" pptx

... to inhibit effects of cigarette smoke on airway defense by restoring IFN-γ-dependent antiviral effects. Discussion Epithelial cells in the airway are often targeted by respira- tory viruses, and ... for each sample. Epithelial Cytotoxicity Assays Mitochondrial activity was assessed by quantification of 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphe- nyl)-2-(4-su...

Ngày tải lên : 12/08/2014, 11:22

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Báo cáo y học: "Inhibition of breathing after surfactant depletion is achieved at a higher arterial PCO2 during ventilation with liquid than with gas" ppsx

... study a ventilatory strategy of a moderate PEEP (0.5 kPa) and positive pressure ventilation at 60/ min was chosen in a model of surfactant depletion to sim- ulate a relevant clinical situation ... inspira- tory activity is inhibited at higher peak airway pressures and tidal volumes after lung lavage than before. In cats with surfactant- depleted lungs, inhibit...

Ngày tải lên : 12/08/2014, 18:21

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Báo cáo y học: "Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal" pot

... purposes) Retrovirology Open Access Research Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal Aviad Levin †1 , Ayelet Armon-Omer †1,4 , ... PCR amplification from pT7-7-180-IN. The primers used were: 5'BsrGI: 5'-CCGCCATGTACAAA- GAGCTCAAAAAAATCATCGGTCAG-3' 3 BsrGI: 5&apo...

Ngày tải lên : 12/08/2014, 23:22

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Báo cáo y học: " Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120" docx

... purposes) Retrovirology Open Access Research Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120 James M Binley 1 , Stacie Ngo-Abdalla 2 , Penny Moore 3 , ... effectively, if imper- fectly, by measuring Fc-gp120-DC-SIGN binding. Binding of Fc-gp120 chimeras to cellular CCR5Figure 3 Binding o...

Ngày tải lên : 13/08/2014, 09:20

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Báo cáo y học: "Inhibition of early steps in the lentiviral replication cycle by cathelicidin host defense peptides" pptx

... of 12 (page number not for citation purposes) Retrovirology Open Access Research Inhibition of early steps in the lentiviral replication cycle by cathelicidin host defense peptides Lars Steinstraesser* 1 , ... occurring HDPs representing different classes for inhibition of early, Env-independent steps in the HIV replication cycle. A lentiviral vector-ba...

Ngày tải lên : 13/08/2014, 13:20

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