Báo cáo khoa học: "Pro-Con Debate: Steroid use in ACTH non-responsive septic shock patients with high baseline cortisol levels" potx

... on albumin or corticosteroid-binding globulin levels, the increment in total cortisol following ACTH directly reflects the increment in cortisol synthesis, and thus one can use delta cortisol (cosyntropin ... uncertainties lead to ongoing clinical equipoise regarding the use of steroids in patients with septic shock [26]. Until rigorous definitions and diagnostic too...

Ngày tải lên: 12/08/2014, 23:22

... Academic preparation in the principles of EBP appears to distin- guish high- level users from moderate-level users of research in clinical decisio n making. Our research find- ings in this and in previous ... facility support was independently associated with three EBP behaviors: searching, reading [21], and, in this study, using research findings in clinical decision making, b...

Ngày tải lên: 10/08/2014, 10:23

... transfected individually or in combination into ldlD cells and immunoprecipitation was carried out with myc antibody using detergent-soluble cell lysates containing the amount of protein indicated. ... proteins was not cell-type-specific. Aggresomes are structures formed in the presence of misfolded proteins and con- tain components of the protein degradation and refold- ing machinery, i...

Ngày tải lên: 07/03/2014, 00:20

... mine the identity and location of the nucleotide insertion. Four mutants obtained contained in- frame insertions resulting in the insertion of five amino acids into the Cdc37 protein. Stop ... middle and all of the C-terminal domains, including the postulated Hsp90-binding and dimerization regions [16]. Mutants with truncations extending into the N-terminal domain, Cdc37(1–155), Cdc37(1–1...

Ngày tải lên: 16/03/2014, 22:20

... least C-terminally swapped) ds-RNase A dimers are sug- gested to bind two RI molecules in vitro, resulting in an inactive complex [19], BS-RNase evades RI binding [14,21]. To elucidate the mode of binding ... shown in orange, and the linker is shown in blue. (B) The amino acids within the RATEs are numbered 1–124 for the N-terminal RNase A entity and 1¢–124¢ for the C-terminal RNase A...

Ngày tải lên: 22/03/2014, 16:21

... neuroglobin and cytoglobin in a situation of chronic hypoxia in mice were examined using real-time quantitative PCR. The kinetics of the hypoxic expression of neuroglobin (brain, eyes) and cytoglobin ... and pro- tein level was studied in second order. As can be seen in Fig. 3, in eyes, during hypoxic incubation, H 2 O 2 production remained at levels comparable with norm- oxia. Th...

Ngày tải lên: 23/03/2014, 09:21

... oxidoreductase protein (461 amino acids) contains a FAD-binding N-terminal domain and a C-terminal d-arabinono-1,4-lactone oxidase (ALO) signature from T423 to L458. The ALO domain is characteristic ... first-line antituberculosis drug, does not interfere with the synthesis of d-arabinose, but rather inhibits the incorporation of d-arabinofurano- syl residues of decaprenyl-phospho-arabinose...

Ngày tải lên: 30/03/2014, 04:20

... another. After training has been completed, we retain only the joint model’s parameters. Our resulting joint model is of higher quality than a comparable joint model trained on only the jointly-annotated ... sampling. In Machine Learning, volume 28. R. Caruana. 1997. Multitask learning. In Machine Learning, volume 28. Michael Collins. 1997. Three generative, lexicalised models for statist...

Ngày tải lên: 30/03/2014, 21:20

... physiognomy. The surrounding vegeta- tion that continued to be burnt at 1- to 2-year intervals maintained the original open structure (Campo Cerrado). Cerradão presented higher tree density, taller ... important factor in structuring these ecosystems, and fire recurrence has been consid- ered a limiting factor in biomass development and accu- mulation [8, 15]. In spite of being one of t...

Ngày tải lên: 08/08/2014, 14:21

... effects on pollen germination of forest species. In: Sexual Reproduction in Higher Plants (Cresti M, Gori P, Pacini E, eds), Springer-Verlag, Berlin, 265-270 Brewbaker JL, ... F, Gregorius HR, Rudin D, eds) Springer-Verlag, Berlin, 29-37 The extent of reduction increased with in- creasing doses, until 0% germination was reached at 7 mg/l for the...

Ngày tải lên: 08/08/2014, 19:21