... properties of statistical in- ference and underpins the basis of probability theory [18, 19]. Gotway and Young [17] outline a combination of spatial smoothing and geostatistical upscaling or aggregation ... 2007.06.28 We investigated changes in the geography of Chronic Obstructuve Pulmonary Disease (COPD) hospitalization charges in California over the period...
Ngày tải lên: 26/10/2012, 09:57
... its initial effect on protein kinases phosphorylation. The most strikingly and novel finding obtained hereby was the strong inhibition of the GPCR signaling pathway induced mainly by increased ... regulatory role of this pathway in ethanol- induced apoptosis. Taking these data together, we propose a regulatory mechanism of ethanol- induced apoptosis in HepG2 cells (a...
Ngày tải lên: 31/10/2012, 15:37
Báo cáo y học: "Different effect of exercise on left ventricular diastolic time and interventricular dyssynchrony in heart failure patients with and without left bundle branch block"
... increase in intra-LV dyssynchrony was also demonstrated during pharmacological stress in systolic heart failure patients with normal QRS dura- tion. The prevalence of dyssynchrony was low in ... test, interventricular dyssynchrony Introduction The introduction of cardiac resynchronization therapy has recently renewed the clinical interest in the analysis of...
Ngày tải lên: 05/11/2012, 11:32
Tài liệu Báo cáo Y học: Functional analysis of a small heat shock/a-crystallin protein from Artemia franciscana docx
... heat shock /a- crystallin protein from Artemia (Eur. J. Biochem. 269) 937 Functional analysis of a small heat shock /a- crystallin protein from Artemia franciscana Oligomerization and thermotolerance Julie ... 19051–19058. 59. MacRae, T.H. & Liang, P. (1998) Molecular characterization of p26, a cyst-specific, small heat shock /a- crystallin protein f...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli doc
... Together, these data indicate that the helix breaker in cleavable signal sequences prevents recognition by SRP and is thereby, together with the hydrophobicity of the signal sequence, a determinant ... H.C. & Bernstein, H.D. (2001) The targeting pathway of Escherichia coli presecretory and integral membrane proteins is specified by the hydrophobici...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Coordinated action of protein tyrosine phosphatases in insulin signal transduction potx
... coordinate their ac tion on the insulin signaling pathway remains to be determined. Ó FEBS 2002 Protein tyrosine phosphatases in insulin signaling (Eur. J. Biochem. 269) 1055 MINIREVIEW Coordinated ... 2002 Protein tyrosine phosphatases in insulin signaling (Eur. J. Biochem. 269) 1057 context, recruit signaling m olecules containin g SH2 ( Src homology 2) or PTB (pho...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: Identification of mammalian-type transglutaminase in Physarum polycephalum Evidence from the cDNA sequence and involvement of GTP in the regulation of transamidating activity potx
... of mammalian-type transglutaminase in Physarum polycephalum Evidence from the cDNA sequence and involvement of GTP in the regulation of transamidating activity Fumitaka Wada 1 , Akio Nakamura 2 , ... might be similar to that by which they inhibit the enzymatic activity of TGase 4. Hydrolysing activity of GTP was also found in the purifi...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: Detailed characterization of polydnavirus immunoevasive proteins in an endoparasitoid wasp doc
... K. Tanaka et al. (Eur. J. Biochem. 269) Ó FEBS 2002 Detailed characterization of polydnavirus immunoevasive proteins in an endoparasitoid wasp Kohjiro Tanaka, Hitoshi Matsumoto and Yoichi Hayakawa Institute ... Immunodetective analyses of C. kariyai polydnavirus and immunoevasive activity of IEPs. (A) Left, immunogold staining of CkPDVs on the wasp egg with an...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo Y học: Antiproliferative proteins of the BTG/Tob family are degraded by the ubiquitin-proteasome system docx
... of BTG/Tob family proteins are situated on the conserved N-terminal BTG/Tob homology domains, because BTG1, BTG2, Tob, and Tob2 proteins are all degraded by the ubiquitin–proteasome system and the ... levels of BTG1 and BTG2 mRNAs increase in the early G1 phase of the cell cycle [4,5] and that BTG/Tob family proteins are involved in G1 arrest [7,11,...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo Y học: Structural heterogeneity of pyrimidine/purine-biased DNA sequence analyzed by atomic force microscopy potx
... PRIORITY PAPER Structural heterogeneity of pyrimidine/purine-biased DNA sequence analyzed by atomic force microscopy Mikio Kato 1,2 , Chad J. McAllister 2 , Shingo Hokabe 1 , Nobuyoshi Shimizu 3 and ... solution. Recently, we have successfully characterized the intramo- lecular triplex structure formed in supercoiled DNA within 46 bp of Pyr/Pur mirror symmetry by...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: " Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke" pot
... with COPD. The effect of cigarette smoke was replicated in vitro by examining TLR4 mRNA and protein expression and quantifying IL-8 expression in airway epithelial cells stim- ulated with cigarette ... characterise this disease. TLR4 expression is modu- lated both by drugs used to treat airways inflammation and by cigarette smoke, the major pathogenic de...
Ngày tải lên: 12/08/2014, 15:21
Báo cáo y học: " Visualizing fusion of pseudotyped HIV-1 particles in real time by live cell microscopy" doc
... for investigating viral fusion at the cell membrane by live cell microscopy. Visualization of individual fusion events by single particle tracing After monitoring overall virus -cell fusion by ... Env protein by the viral protease is necessary to render Env fusion- competent. By using a cell- cell fusion assay, particles bearing Env.YFP and deficient in prote...
Ngày tải lên: 12/08/2014, 23:22
Báo cáo y học: "Nuclear import of Avian Sarcoma Virus integrase is facilitated by host cell factors" pdf
... This hypothesis was tested in a variety of ways. Competition experiments with ASV IN mediated import is inhibited by excess histone H1Figure 5 ASV IN mediated import is inhibited by excess his- tone ... BioMed Central Page 1 of 14 (page number not for citation purposes) Retrovirology Open Access Research Nuclear import of Avian Sarcoma Virus integrase is facilit...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo y học: "Cost-effectiveness of activated protein C in real-life clinical practice" potx
... Ryan TJ, Cleary PD, McNeil BJ: Validating recommendations for coro- nary angiography following acute myocardial infarction in the elderly: a matched analysis using propensity scores. J Clin Epidemiol ... the costs of treating patients without using rhAPC. The secondary objective was to determine the cost-effectiveness of rhAPC in real-life clinical practice. In the present study...
Ngày tải lên: 13/08/2014, 08:20
Báo cáo y học: " The burden of acute respiratory infections in crisis-affected populations: a systematic review" doc
... in a referral hospital in Liberia 1 year after the end of the war. Transactions of the Royal Society of Tropical Medicine and Hygiene 2009, 103(5):476-484. 49. Tanaka H, Oda J, Iwai A, Kuwagata ... Kuwagata Y, Matsuoka T, Takaoka M, Kishi M, Morimoto F, Ishikawa K, Mizushima Y, Nakata Y, Yamamura H, Hiraide A, Shimazu T, Yoshioka T: Morbidity and mortality of hospita...
Ngày tải lên: 13/08/2014, 14:20