Báo cáo khoa học: "The key advance in the treatment of sepsis in the last 10 years … doing less" pot

... the greatest single advance in patient management in the intensivecare unit in the past 10 years. Although certainly not qualifying as a‘brave new world’ in terms of daring and exciting innovation, the importance ... advance in the treatment of sepsis in the last 10 years … doing lessMervyn SingerUniversity College London, Gower St, London WC1E 6BT, UKCorresponding author: Mervyn Singer, m.singer@ucl.ac.ukPublished: ... with an increasing emphasis on mono-therapy. Less nutritional neglect but also less persistencewith enteral feeding in the presence of gastrointestinalintolerance. Less acceptance of high...

Báo cáo khoa học: Xenopus Rbm9 is a novel interactor of XGld2 in the cytoplasmic polyadenylation complex pptx

... activation of the complex, which allow PAP to elongate the poly(A) tail[6,7]. Then, the poly(A) tail binds to the poly(A)-bind-ing protein (PABP), which brings in eIF4G, thusallowing the positioning ... arginine ⁄ glycine-rich(RGG) motifs that are characteristic of RNA-bindingproteins, and an alanine-rich carboxy-terminal sequencethat could be involved in protein–protein interactions.Interestingly, ... protein was fused to the MS2 coat protein to allow the tethering of XRbm9 toa reporter mRNA bearing a tandem pair of MS2-bind-ing sites. Oocytes were ﬁrst injected with the MS2-XRbm9-encoding...

Báo cáo khoa học: Fission yeast decaprenyl diphosphate synthase consists of Dps1 and the newly characterized Dlp1 protein in a novel heterotetrameric structure doc

... analyze the size of the Dps1–Dlp1 heteromer, weprepared the crude proteins of E. coli expressing the GST–Dlp1 and His–Dps1 fusion proteins and incubated themwith the protein crosslinker disuccinimidyl ... are under the control of the strong nmt1 promoter. pGEXDLP1 contains the entirelength of the dlp1 genefusedwiththeGST gene in pGEX-KG vector.pSTVHISDPS1 contains the entire length of the dps1 ... ubiquinone synthesis (Fig. 3). This encouragingresult indicates that the dlp1 gene is involved in ubiquinonebiosynthesis.Phenotypes of the dlp1disruptantIt was reported previously that KS10...

Báo cáo khoa học: "KNOWLEDGE ORGANIZATION AND APPLICATION: BRIEF COMIIENTS OF PAPERS IN THE SESSION " potx

... objects and their normal uses.lf a non-normal reading of (1) is intended (e.g., the wine bein 0 poured into the bottle) then (l") John opened the bottle and poured the wine into it is ... case. We have the same situation in John took the bottle out of the refrioerator and poured the w-Tne. The inference here is dependent on knowing something about wine bottles and their normal ... that of Schank. Knowledge about objects, their normal uses, and the kinds of actions they are normally involved in is necessary for interjretation of sentences dealing with objects. In sentence...

Báo cáo khoa học: "A research algorithm to improve detection of delirium in the intensive care unit" pdf

... ill patients[3,9 ,10] . The CAM-ICU and the Intensive Care DeliriumScreening Checklist [11] are the current standard instrumentsfor detecting delirium in the ICU. In the absence of suchassessments, ... from the National Institute on Aging. Dr Elyis a recipient of an NIH K23 award from the NIA (K23 AG01023-01A1). None of the authors has a financial or other poten-tial conflict of interest. Key ... performed the chart-based abstraction, and this may bea potential source of bias and limit the generalizability of the findings. As with any single-site study, the generalizability of the results...

Báo cáo khoa học: Puriﬁcation, characterization and molecular cloning of tyrosinase from the cephalopod mollusk, Illex argentinus docx

... areinvolved in the system as in the case of the arthropodproteins.It remains unclear whether C-terminal cleavage isinvolved in the activation of ST94. For tyrosinases fromplant and fungi, the ... one of the ligands in the Cu(A) site is involved in the cysteine-histidinethioether bridge [55]. This unusual linkage in the copper-binding site has also been observed in ascomycete tyrosin-ases, ... tyrosinase activity of 23.5 U per mg protein.Activation of ST94 by treatment with trypsinAs described above, most of the tyrosinase activity in the ink of I. argentinus originated from tyrosinase-active...

Báo cáo khoa học: "Experimental peritonitis induced by oral administration of indomethacin in Mongolian gerbils" ppt

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Báo cáo khoa học: "Pulmonary echinococcosis mimicking multipl lung metastasis of breast cancer: The role of fluoro-deoxy-glucose positron emission tomography" pot

... charac-terize this kind of lesionsCompeting interests The author(s) declare that they have no competing inter-ests.Authors' contributionsYK drafted the manuscript, ÝS helped in preparing the manuscript, ... foralveolar echinococcosis [1,2]. Parasitic eggs turned to lar-vae form after ingestion in the intestine and migrate to the other organs by penetrating intestinal wall and thendevelop cystic ... characterizing indeterminate pulmonary nodules >1 cm is very helpful tocharacterize this kind of lesions.BackgroundEchinococcosis is a parasitic infestation caused by larvae of the tapeworm echinococcus....

Báo cáo khoa học: "A System for Large-Scale Acquisition of Verbal, Nominal and Adjectival Subcategorization Frames from Corpora" pot

... for lin-guistic annotation of SCFs in corpus data aimed atalleviating the process of obtaining training and testdata for subcategorization acquisition. The tool in- corporates an intuitive interface ... is the NP of the PP. The only part of the featurestructure which is not represented by the GRs is coin-dexation between the omitted direct object1 of the VP-complement and the subject of the ... Ac-cording to the COMLEX classiﬁcation, this is an ex-ample of the frame adj-obj-for-to-inf, shown in Figure 2, (using AVM notation in place of COMLEXs-expressions). Part of the output of RASP...

Báo cáo khoa học: "Pulse high-volume haemofiltration for treatment of severe sepsis: effects on hemodynamics and survival" doc

... have been dis-appointing [29]. Almost paralleling the surge in proinflammatory mediators, there is a rise in anti-inflammatorysubstances, resulting in induction of a state of immunoparaly-sis ... can hypothesize that the use of activated protein C (drot-recogin alfa [activated]) in 50% of the population might havecontributed to the improved outcome. If so, then the combina-tion of activated ... http://ccforum.com/content/9/4/R294R300gle mediators nor single-dose interventions therefore seemappropriate, in part because of a discrepancy between the biological timing of the syndrome and the clinical timing of symptoms.CRRT...

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