Báo cáo y học: " Complementation of diverse HIV-1 Env defects through cooperative subunit interactions: a general property of the functional trimer" potx
Báo cáo y học: " Complementation of diverse HIV-1 Env defects through cooperative subunit interactions: a general property of the functional trimer" potx
... through cooperative subunit interactions: a general property of the functional trimer Karl Salzwedel 1,2 and Edward A Berger* 1 Address: 1 Laboratory of Viral Diseases, National Institute of Allergy ... multi-nucleated syncytia per well with the aid of a grid. For the virus entry assays, p24 levels in the filtered supernatants were quantitated using the...
Ngày tải lên: 12/08/2014, 23:22
Báo cáo y học: "Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain"
... hyperalgesia The paw withdrawal latency (PWL) to radiant heat and paw withdrawal threshold (PWT) were used to evaluate thermal hyperalgesia and mechanical al- lodynia respectively as previously ... transfection reagent (Neuromics, Edina, MN, USA) was administered intrathecally once daily for 7 days, starting from 1 day before CCI surgery. Evaluation of tactile allodynia and thermal...
Ngày tải lên: 25/10/2012, 11:48
Báo cáo y học: " Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma" potx
... a standard curve using the authentic compounds as external standards. Statistical analysis Data wer e analyzed using an analysis of variance and for post hoc comparisons of means a Newman-Keuls ... induce symptoms of a sthma such as ozone and Cl 2 cause oxidant injury, in particular to the airway epithelium. Desquamation of the airway epithe- lium and prolonged sub-epithel...
Ngày tải lên: 12/08/2014, 11:22
Báo cáo y học: "Circulating immune complexes and complement C3 and C4 levels in a selected group of patients with rhinitis in Lebanon" pot
... the absorbance of the turbidity produced at a wavelength of 450 nm using patients' serum as a blank. The results obtained paralleled those obtained when the C 1q assay was used. The absorbance ... that the complement system is activated by the allergen or the immune complex and the anaphyla- toxins, C 3a, C 4a and C 5a produced contributes to the severity...
Ngày tải lên: 13/08/2014, 13:22
Báo cáo Y học: Irregular spiking in free calcium concentration in single, human platelets Regulation by modulation of the inositol trisphosphate receptors ppt
... Histogram of variation in peak-to-peak interval of 15 responsive platelets. (D) Plot of total duration of individual peaks (90% decay) vs. peak amplitude. Data are mean values plus SEM of analysis results ... permitting a simultaneously high tem- poral and spatial resolution of the Ca 2+ signal, clearly indicated that the [Ca 2+ ] i release events in platelets are highly irr...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the a or b catalytic subunit potx
... inactive state, the CaN autoinhibitory domain lies over the catalytic site [20]. The amino-acid sequences of the CnAa and CnAb catalytic domains are 90% identical, and the autoinhibitory domain ... substrate. The functional differences conferred upon CaN by the a or b catalytic subunit isoforms suggestthatthea:b and CaN:substrate ratios may determine the levels of CaN...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: " Multiple functions for CD28 and cytotoxic T lymphocyte antigen-4 during different phases of T cell responses: implications for arthritis and autoimmune disease" pot
... inhibition of early T cell activation is dispensable [11]. Second, whereas only a fraction of activated T cells express CTLA-4 at the cell surface, CTLA-4 has additional functions in already activated ... M, Komata T, Matsuta K, Zama K, Oka T, Juji T, Yamane A, Tokunaga K: Lack of a strong associ- ation of CTLA-4 exon 1 polymorphism with the susceptibility to rheumatoid arthr...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes" pptx
... with active RA. All the patients with RA satisfied the 1987 revised diagnostic criteria of the American College of Rheumatology [12]. The mean age of the RA patients was 58 years (range 28–76 years) ... OA. The mean age of these patients was 51 years (range 46–57 years) and the mean disease duration was 12 years. The normal control samples of peripheral blood were ta...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Leukocyte numbers and function in subjects eating n-3 enriched foods: selective depression of natural killer cell levels" potx
... using a plate reader (Dynatech MR7000, Dynatech Laboratories, Chantilly, VA). The degree of adherence was calculated by subtracting the mean absorbance values of blank wells from the mean of the test ... University of South Australia, Australia, Adelaide SA 5000, Australia 4 Discipline of Paediatrics, University of Adelaide, 72 King William Road, North Adelaide SA 5006,...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Interferon-induced protein IFIT4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into dendritic cell-like cells" pdf
... purposes) ward: 5'-AACTACGCCTGGGTCTACTATCACTT-3'; IFIT4 reverse: 5'-GCCCTTTCATTTCTTCCACAC-3'; GAPDH for- ward: 5'-GAAGGTGAAGGTCGGAGTC-3'; GAPDH reverse: 5'-GAAGATGGTGATGGGATTTC-3'. ... Mann-Whitney test was used to analyze these data. (j) The relative expression of IFIT4 was plotted against Systemic Lupus Erythematosus Disease Activity Index-2,000...
Ngày tải lên: 09/08/2014, 10:23