... production and the endogenous levels of ICDs were not reduced by deletion of BACE1. In fact, in most cases, deletion of BACE1 resulted in an increase in the levels of ICDs. Indeed, treatment of cultured ... frozen in liquid nitrogen, and stored at )80 °C until analysis. Levels of BACE1 protein in all of the brain tissues analyzed were assessed by western blotting...
Ngày tải lên: 15/03/2014, 10:20
... unknown. Measurement of cTnI levels in cases where an evaluation of the heart muscle status is indicated can be valuable for adjusting treatment and monitoring of the individual dog. This is relevant for ... many mammalian species including humans, dogs and cats [6- 8]. Troponins are intracellular contractile-regulating pro- teins in muscle cells and the isoenzyme cTnI is sp...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo khoa học: Sp3 transcription factor is crucial for transcriptional activation of the human NOX4 gene doc
... [12,13]. This led us to undertake an investigation of the molecular basis of the constitutive and ubiquitous expression of NOX4 in human tissues. We report here the predominant role of the transcription ... nuclear extracts obtained from SH-SY5Y and HEK293 cells. As shown in Fig. 5A, the binding of nuclear proteins to GC-boxes 1 and 2 was detected by doublet bands in both ce...
Ngày tải lên: 29/03/2014, 00:20
Báo cáo khoa học: "bcl-2 expression is not associated with survival in metastatic cutaneous melanoma: A historical cohort study" pptx
... the distribution of patients in terms of pri- mary diagnosis and location of tumor and first metastasis. Mean age at initial diagnosis was 43 years, ranging from 16 to 74 years, with a median of ... family in the study of Caenorhabditis elegans, opened new perspectives for the study of tissue morphogenesis and oncogenesis [9,11,18]. Inhibition of apoptosis can occur in a...
Ngày tải lên: 09/08/2014, 07:21
Báo cáo khoa hoc:" Resting energy expenditure is not influenced by classical music" ppsx
... REE between silence and the two music periods. This study could not detect any statistical significant or clinical relevant influences of music on REE, and then the- oretically not on total energy ... Diet induced thermogenesis. Nutr Metab 2004, 1:5. 5. Jessen AB, Toubro S, Astrup A: Effect of chewing gum containing nicotine and caffeine on energy expenditure and substrate utilization...
Ngày tải lên: 11/08/2014, 08:20
báo cáo khoa học: "Apple skin patterning is associated with differential expression of MYB10" ppsx
... with anthocyanin accumulation and are higher in red fruit Coumaroyl-Co-A Dihydroflavonols P h eny l a l anine Hydroxycinnamic acid Chalcones Flavanones Leucoanthocyanidins Anthocyanidins Anthocyanins Dihydrochalcones Flavonols Flavan-3-ols Condensed ... Red’,asportof Figure 2 Different types of fruit peel pigment p atterns in ‘Honeycrisp’ apple. Distribution of anthocyanin in apple...
Ngày tải lên: 11/08/2014, 11:20
Tài liệu Báo cáo khoa học: "The Arabic Online Commentary Dataset: an Annotated Dataset of Informal Arabic with High Dialectal Content" pdf
... clas- sification via text -independent training and testing for arabic, spanish, and chinese. IEEE Transactions on Audio, Speech, and Language Processing, 19(1):85– 96. Omar F. Zaidan and Chris Callison-Burch. ... distinguishing each dialect from the corresponding MSA content, and distinguishing the dialects from each other. We should note that, in practice, accuracy is prob- ably not a...
Ngày tải lên: 20/02/2014, 04:20
Báo cáo khoa học: The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism docx
... immune and neuroendo- crine activities, and tumorostatic and anticarcinogenic properties, affecting proliferation, differentiation and apoptosis in cells of different lineages, and protecting DNA ... (Christ, Germany). The residues were dissolved in methanol and subjected to LC-MS analysis. NMR Samples were dissolved in CDCl 3 (Cambridge Isotope Laboratories, Inc., Andover, MA) [17]....
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: "INTEGRATING MULTIPLE KNOWLEDGE SOURCES FOR DETECTION AND CORRECTION OF REPAIRS IN HUMAN-COMPUTER DIALOG*" potx
... pattern matching, syntactic and semantic analy- sis, and acoustic analysis can be helpful in detect- ing and correcting these repairs. We use pattern matching to determine an initial set of possible ... sults of combining the acoustic constraints just de- scribed. As can be seen, such features in combina- tion can be quite helpful in distinguishing repairs from false posit...
Ngày tải lên: 31/03/2014, 06:20