Báo cáo y học: "Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA" potx

... Access Research Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA Yeshitila N Friew, Vitaly Boyko, Wei-Shau Hu and Vinay K Pathak* Address: ... Transfection with NY-A3G and CY-A3G resulted in YFP reconstitution with a similar efficiency (89%). Reconstitution of YFP fluores-...

Ngày tải lên: 12/08/2014, 23:21

... S: Isolation of human mononuclear cell subsets by counter flow centrifugal elutriation (CCE). I. Characterization of B-lymphocyte, T-lymphocytes and monocyte-enriched frac- tions by flow cytometric ... consistent with active MMPs, and was associated with augmentation of both contraction and degradation (P < 0.01). PGE 2 appeared to decrease both MMP production and activation....

Ngày tải lên: 12/08/2014, 18:20

... drafting and revising the manu- script. VN assisted in designing the experiments and in data anal- ysis, assisted in calculations for the theoretical analysis, and contributed in drafting and revising ... was defined by the association rate constant k association identical for both sites, k association = 1.35 × 10 8 M -1· s -1 . The assigned dissociation rate constants, k di...

Ngày tải lên: 13/08/2014, 16:21

... N-[(N 6 -benzoyladenin-9-yl)acetyl]-N-[2-[(4-meth- oxytrityl) amino] ethyl]glycinate, tetrabutylammonium N-[(N 2 -isobutyrylguanin-9-yl)acetyl]-N-[2-[(4-methoxy- trityl) amino]ethyl] glycinate, tetrabutylammonium ... family was performed by energy minimization and molecular dynamics simulations, and interactions between PNA–DNA chimeras and NF-kB proteins were studied by electrophor...

Ngày tải lên: 24/03/2014, 04:21

... positioning. Based on the pooled results in this study and our previous contributions to this subject, we conclude with a working hypothesis. Glycosaminoglycans released from connective tissues by the action ... sulfated polysaccharides resulted in concentration -dependent inhibition of the enzyme activity. We used semi-synthetic glycosamino- glycan derivatives of precisely defined isom...

Ngày tải lên: 16/02/2014, 14:20

... cells play a key role in the control of viral repli- cation during HIV-1 infection. The cytotoxic T lympho- cyte (CTL) response is mainly measured at the early stage of infection and its a ppearance ... anti-Human Immunodeficiency Virus Type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1 -infected long-term nonpro...

Ngày tải lên: 12/08/2014, 01:21

... mechanisms (for example, stasis and genetics) and one such mechanism could lead to an inflammatory reaction that would amplify thrombin genera- tion with the likely consequence of a more stable, ... Nilsson J-A, Svensson PJ: Location and extent of deep vein thrombosis in patients with and without FV:R 506Q mutation. Thromb Haemost 2000, 83:648-651. 23. Moser KM, Lemoine JR. Is e...

Ngày tải lên: 12/08/2014, 18:20

... participa- tion was sent electronically to attending physicians (either Division Chiefs or other faculty) at different cen- ters between January and May 2009. Surveys were con- ducted primarily by phone ... January to May 2009. Surveys were conducted by phone between the investigators and participating centers and consisted of a 22-point questionnaire devised to assess physician per...

Ngày tải lên: 13/08/2014, 20:21

... to solve is underspecified. That is, in the same context, more than one description can be potentially used. Mutually interchangeable descriptions in- clude synonyms and near synonyms ("leader" ... descriptions based on our algorithm is feasible even though the val- ues of precision and recall obtained may seem only moderately high. The reason for this is that t...

Ngày tải lên: 17/03/2014, 07:20

... participated in its study and coordination. All authors read and approved the final manuscript. Author Details 1 Yonago Medical Corporation, Yonago Clinic, Yonago, Tottori, Japan, 2 Yakumo Hospital, ... 150 mg, and her delusions began to gradu- ally decrease and finally disappeared completely. After recovery, risperidone treatment was stopped. Treatment with fluvoxamine (150 mg)...

Ngày tải lên: 08/08/2014, 23:21