Báo cáo y học: " Proteasome-independent degradation of HIV-1 in naturally non-permissive human placental trophoblast cells" pptx
Báo cáo y học: "The characterisation of mucin in a mature ovarian teratoma occurring in an eight year old patient
... enhanced in 1% copper sulphate for 10min. Finally, sections were counterstained in Mayer’s haematoxylin, dehydrated through the as- cending graded alcohols, cleared in xylol and finally coverslipped ... feature of various cancers including cancer of the co- lon [33]. The amino acid analysis of the purified mucin gave high amounts of ‘mucin-like amino acids, serine, threoni...
Ngày tải lên: 26/10/2012, 10:03
Báo cáo y học: " Mutation Analysis of hCDC4 in AML Cells Identifies a New Intronic Polymorphis"
... Biochemistry of the Charité, Berlin, Germany using the ABI PRISM Big Dye Terminator system (Applied Biosystems, Germany). Sequences were analyzed using the Chromas software (Technely- sium Pty Ltd, ... pathogenesis of AML. During sequence analysis of exon 10 in the AML samples we identified a new intronic SNP which we subsequently confirmed by sequencing DNA samples of 51 heal...
Ngày tải lên: 31/10/2012, 16:49
Báo cáo y học: "Antiviral therapy of HCV in the cirrhotic and transplant candidate"
... against Cirrhosis), is a multicenter study of the potential benefit of prolonged peginterferon therapy in mitigating the progression of fibrotic liver disease. [8] In this study, 391 of the ... factors, specifically G-CSF and erythropoietin, has allowed more aggressive dosing of interferon and ribavirin. [13, 14] Finally, growing experience with antiviral therapy in thi...
Ngày tải lên: 31/10/2012, 17:11
Tài liệu Báo cáo Y học: Re-oxygenation of hypoxic simian virus 40 (SV40)-infected CV1 cells causes distinct changes of SV40 minichromosome-associated replication proteins doc
... origin in hypoxic and in re-oxygenated cells. T antigen-catalysed unwinding of the SV40 origin occurred, however, only after re-oxygenation as indicated by (a) increased sensitivity of re-oxygenated minichromosomes ... remained unchanged in SV40-infected CV1 cells during a 4-h hypoxic incubation, whereas unwinding, as determined by generation of SV40 form U, and incorporation of...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: Identification of residues in the PXR ligand binding domain critical for species specific and constitutive activation docx
... ligand binding domains. By modeling the human PXR ligand binding domain we have identified and mutated two polar residues in the puta- tive ligand binding pocket which differ between the human and ... determinant for the transcrip- tional regulation of the drug metabolizing enzyme family of heme-containing monooxygenases P450 CYP3A [1–4]. Consequently this nuclear receptor is likely t...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: The mechanism of nitrogen monoxide (NO)-mediated iron mobilization from cells NO intercepts iron before incorporation into ferritin and indirectly mobilizes iron from ferritin in a glutathione-dependent manner pot
... isonicotinoyl hydrazone class as effective antiproliferative agents II. The mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydrazone. ... Further, Rogers and Ding [48] have shown that L -cysteine is necessary for the removal of dinitrosyl–Fe complexes from [Fe–S]-containing proteins in Escherichia coli. Interesting...
Ngày tải lên: 08/03/2014, 22:20
Báo cáo Y học: Molecular cloning of columbamine O-methyltransferase from cultured Coptis japonica cells pot
... tetrahydrocolumbamine using this 80% pure tetrahydrocolumbamine. To quantify the enzymatic activity of CoOMT, the transfer of the 3 H-labeled methyl group of S-adenosyl- L - [methyl- 3 H]methionine ... S-adenosyl- L -methionine: coclaurine N-methyltransferase; 4¢OMT, S-adenosyl- L -methionine:3¢- hydroxy-N-methylcoclaurine 4¢-O-methyltransferase; SMT, S-adenosyl- L -methionine:scoulerin...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: The role of zinc in the methylation of the coenzyme M thiol group in methanol:coenzyme M methyltransferase from Methanosarcina barkeri New insights from X-ray absorption spectroscopy doc
... to ligation of the thiol group of coenzyme M. Mutations in His237 or Cys239, which are proposed to be involved in ligating zinc, resulted in an over 90% loss in enzyme activity and in distinct changes in ... & Penner-Hahn, J.E. (1998) Characterization of the zinc binding site in methionine synthase enzymes of Escherichia coli – the role of zinc in the methylation...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: Amidolytic activity of prostatic acid phosphatase on human semenogelins and semenogelin-derived synthetic substrates docx
... (PSA) is an insulin-like growth factor binding pro tein-3 protease fo und in seminal plasma. J. Clin. Endocrinol. Metab. 75, 1046±1053. Fig. 3. Hydrolysis of puri®ed semenogelin I by PAP. HPLC ... those of hK3 and were mainly at P1 Gln residues or b etween residues bearing hydroxyl groups. PAP amidolytic activity was poorly inhibited by all currently used wide spectrum proteinase inhi...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo Y học: Stimulated biosynthesis of flavins in Photobacterium phosphoreum IFO 13896 and the presence of complete rib operons in two species of luminous bacteria Sabu Kasai and Takumi Sumimoto pot
... Chemistry, Faculty of Engineering, Osaka City University, Japan Photobacterium phosphoreum IFO 13896 emits light strongly when cultured in medium containing 3% NaCl, but only weakly in medium containing ... pyrimidine deaminase/pyrimidine reductase, riboflavin synthase, GTP cyclohydrolase II/3,4-dihydr- oxy-2-butanone 4-phosphate synthase, and lumazine syn- thase. The genes coding for th...
Ngày tải lên: 31/03/2014, 08:20