Báo cáo y học: " Synergistic effect of human CycT1 and CRM1 on HIV-1 propagation in rat T cells and macrophages" docx

... efficiently than hCycT1, in contrast to the effects of the two proteins in rat T cell lines.Infectivity of HIV-1 produced by rat cells To investigate whether HIV-1 produced by rat cells is infec-tious, ... from hCycT1/ CRM1 Tg ratsTo investigate the effects of hCycT1 and hCRM1 on p24production in primary T cells, we prepared T cells fromsplenocytes of wild-type (WT) and Tg rats and stimulatedthem ... during the activation of human lymphocytes[33], we stimulated the splenocytes with anti-CD3 and anti-CD28. Expression of hCycT1 was detected within 1 Synergistic effect of hCycT1 and hCRM1 in rat...

Báo cáo y học: " The effect of maternal common mental disorders on infant undernutrition in Butajira, Ethiopia: The P-MaMiE study" pot

... month rather than 12 months of age+ unadjusted effect of concurrent CMD at two month time point++ unadjusted effect of two month postnatal CMD on 18 month nutritional status+++ unadjusted effect ... antenatal only, incident postnatal and chronic CMD on infant undernutrition at the age of six and twelve months in the P-MaMiE studyModel Timing for main exposureSix month time point One year time ... effect of concurrent CMD at 18 month of age§ unadjusted effect of postnatal CMD on three month nutritional status§§ Reported effects are on nutritional status of 6-24 year old childrenET = Ethiopia;...

Báo cáo y học: "The effect of interruption to propofol sedation on auditory event-related potentials and electroencephalogram in intensive care patients" pps

... et al.R490Competing interestsThe author(s) declare that they have no competing interests.Author's contributionsHYP, SN, IK, JP and ER participated in the interpretation of theresults ... midazolam administration discontinued. The opti-mal depth of sedation for each patient was determined on clin-ical grounds, independent of the study, and was assessedusing the sedation–agitation scale ... minafter discontinuation of propofol. Weaning and extubationwere successful in 10 patients, whereas sedation was elec-tively restarted in the remaining nine patients. Of the ERP recordings, 2% and...

Báo cáo khoa học: "The effect of external beam radiotherapy volume on locoregional control in patients with locoregionally advanced or recurrent nonanaplastic thyroid cancer" ppsx

... factors and the effect of treatment with radioactive iodine and external beam radiation on patients with differentiated thyroid cancer seen at a single institutionover 40 years. Clin Endocrinol ... thus, it is needed toevaluate the effect of EBRT volume on locoregional con-trol in nonanaplatic thyroid c ancer patients. Addition-ally, it is important for patients with nonanaplasticthyroid ... radiotherapy (EBRT)remains controversial. Despite conflicting data [1-4], anumber of retrospective studies have demonstrated thatEBRT potentially improves locoregional control in patientswith nonanaplastic...

Báo cáo khoa học: " Synergistic effect of ERK inhibition on tetrandrine-induced apoptosis in A549 human lung carcinoma cells" docx

... USA) at 20 mM as a stock solution and diluted for further analysis.The concentration-dependent effect of TET on the inhibition of A549 cell proliferationThe impact of TET on the viability and ... h. TET treatment significantly reduced the rate of cell proliferation compared to that of control cells in both time-/concentration-dependent manners. The reduction of cell proliferation and ... higher than TET treatment alone and TET with PI3K inhibitor pretreatment. Western blot analysis of Akt and ERK protein levels and activation states confirmed that TET-induced apoptosis may occur...

Báo cáo y học: "Inhibitory effect of IL-8 on insulin action in human adipocytes via MAP kinase pathway." doc

... might affectinsulin sensitivity in adipocytes. To test that possibility,we examined the effect of IL-8 on the insulin-induced Aktphosphorylation in fully differentiated human adi-pocytes. Here, ... a main adi-pocytokine producing insulin resistance via the inhibition of insulin-induced Akt phosphorylation in human adi-pocytes, and the attenuation of IL-8 production and/ oraction may be ... or an antibody to PKB/Akt inhibited the effect of insulin-stimulated GLUT-4 translocation in adi-pocytes [9]. Therefore, it is conceivable that inhibition of insulin-induced Akt activation is...

Báo cáo y học: " The effect of the pro-inflammatory cytokine tumor necrosis factor-alpha on human joint capsule myofibroblasts" ppsx

... demonstrate that TNF-α is capable of inducing cell viability and proliferation in MF cultures.This effect was already present at a low concentration of thecytokine. However, the stimulation of ... Mainz. The authors declare that the study design, the collection and the interpretation of the data, and the presentation of information were not influ-enced by the mentioned organizations or by ... contributed tothe establishment of the MTT assay and the 3D collagen gel model, and helped to perform the statistical analysis and the interpretation of the results.JW contributed to the establishment...

Báo cáo y học: " The effect of interleukin-13 (IL-13) and interferon-g (IFN-g) on expression of surfactant proteins in adult human alveolar type II cells in vitro" docx

... TGTTGCAAGGCGGCATT36B4 CCACGCTGCTGAACATGCT AACATCTCCCCCTTCTCCTTTGGGCTT TCGAACACCTGCTGGATGACDefinition of abbreviations: SP, surfactant proteinFigure 1 IL-13 alters mature SP-C protein level in ... processing and presentation, stimulation of leuko-cyte recruitment, and activation of microbicidal effectorfunctions and a n anti-viral state [36]. In this study, wedemonstrated that IFN-g induces ... of this study is toinvestigate the IL-13 and IFN-g effect on the expression of the surfactant proteins using primary human adultATII cells in monolayer culture in vitro.Theexperi-ments with...

Báo cáo y học: " Biphasic effect of extracellular ATP on human and rat airways is due to multiple P2 purinoceptor activation" ppsx

... recently, a delayed ATP- Effect of indomethacin and H-89 on ATP-induced contraction in rat isolated airway ringsFigure 9 Effect of indomethacin and H-89 on ATP-induced contraction in rat isolated ... 0.05Results Effect of ATP on rat and human isolated airwaysATP induced a fast and transient contraction of rat iso-lated airway rings which amplitude depended on the con-centration of agonist and the ... pro-longs the contractile effect of ATP in trachea and EPB butnot in IPB, show that in extrapulmonary airways, the tran-sient contractile effect of ATP depends, at least in part, on PKA activation,...

Báo cáo y học: "The effect of glutamine infusion on the inflammatory response and HSP70 during human experimental endotoxaemia" pptx

... decline in plasma glutamine after endotoxin injection in thetwo groups. In contrast to our hypothesis, glutamine adminis-tration had no effect on the cytokine or WBC response toendotoxin and ... anti-inflammatory effects of thisprotein. In the present study we hypothesized that intravenous admin-istration of glutamine attenuates the immune response duringacute inflammation. We thus established ... morbidity and mortality in critically ill patients, possibly in partthrough an attenuation of the proinflammatory cytokineresponse and a stimulation of heat shock protein (HSP)70. Weinfused either...

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