Báo cáo khoa học: "Pulse oximeter as a sensor of fluid responsiveness: do we have our finger on the best solution" pot

... by Cannesson andcoworkers [11]. This allowed the investigators to maintain a constant gain throughout the study, rendering quantitativeanalysis of the waveform easier.ConclusionAdditional ... in the ‘pulse’ waverather than that in the peak of the wave. By reflecting the pulsatile changes in absorption of infrared light between the light source and the photo detector of the pulse oximeter, ... the pulse oximetry signal may be of poor quality in the presence of motion, hypothermia or arterial vaso-constriction, although the new generation of pulse oximetersallows one to optimize the...

Báo cáo khoa học: Missense mutations as a cause of metachromatic leukodystrophy Degradation of arylsulfatase A in the endoplasmic reticulum potx

... For that reason we have examined whether inprincipal any of the mutant ASAs can be deliveredfrom the ER upon inhibition of the degradation path-way through inhibition of ER a1 ,2-mann osidase ... acid-substituted ASAsvia the proteasomeIn order to investigate the degradation pathway of amino acid-substituted ASAs in the ER, we used Ltk–Fig. 2. Immunoprecipitation of amino acid-substituted ASAs withstructure-sensitive ... aminoacid-substituted ASAs. The results demonstrate thatall of these mutant ASAs can be partially stabilizedby proteasome inhibition and that the extent of stabilization varies between the substituted...

báo cáo khoa học: "Boerhaave syndrome as a complication of colonoscopy preparation: a case report" ppt

... continuoussuction.Figure 4 A computed tomography (CT ) scan with oral contrastagent (CA) revealed only a thin CA line between the lumen of the esophagus and the mediastinal paraesophageal abscess/CAdepot ... esophagus; ao, aorta).Figure 5 The small perforation on the left side of the esophagus (es) was in a typical location only 2 cm above the esophageogastric border and was intubatable with the ... per-foration at the esophagogastric junction. The initial idea to use vacuum endo-sponge therapy totreat the perforation arose because we have been usingthis kind of interventional therapy successfully...

báo cáo khoa học: "Necrotizing sialometaplasia as a cause of a nonulcerated nodule in the hard palate: a case report" pot

... Open AccessNecrotizing sialometaplasia as a cause of a non-ulcerated nodule in the hard palate: a case reportMônica Ghislaine Oliveira Alves, Dárcio Kitakawa, Yasmin Rodarte Carval ho, Luiz Antonio ... examination, mimics malignant neoplasms.Case report: We report the case of a healthy 25-year-old Cauc asian woman with a three-week history of a painlesslump on her hard palate. Oral examination ... hypothesis was malignant salivarygland tumor; most likely mucoepidermoid carcinomaconsidering the stabbing pain, duration of the lesion andpalpation of a fluctuant area. An incisional biopsy wasperformed....

báo cáo khoa học: "Elevated transaminases as a predictor of coma in a patient with anorexia nervosa: a case report and review of the literature" pot

... Internal Medicine, TMG Asakadai CentralGeneral Hospital, Saitama 351-8551, JapanFull list of author information is available at the end of the articleYoshida et al. Journal of Medical Case Reports ... liver was higher than that of the spleen in a patient with AN and elevated transaminases, wherea sliver steatosis was diagnosed in ultrasound imaging, as was found in our patient. In addition, these ... Open AccessElevated transaminases as a predictor of coma in a patient with anorexia nervosa: a case reportand review of the literatureShuhei Yoshida1,2*, Masahiko Shimada1,3, Miroslaw Kornek2,...

báo cáo khoa học: "Vulval elephantiasis as a result of tubercular lymphadenitis: two case reports and a review of the literature" pptx

... Aeron1, Sidharth Jain1,Nikhil Narayan1, Rahul Bamal1, Yashwant Kumar1, S Srinivas1, Sunita Saxena2AbstractIntroduction: Elephantiasis as a result of chronic lymphedema is characterized ... than one to two percent of the total cases of filarial elephantiasis [7]. Elephantiasis of the femalegenitalia due to other causes is rarer still. We presenttwo unusual cases of vulval elephantiasis ... of past tuberculosis,leading to a blockage of lymphatic d rainage and result-ing in vulval elephantiasis.ConclusionsVulval elephantiasis is very rare, and vulval elephantiasis as a consequence...

báo cáo khoa học: "Emotional stress as a trigger of myasthenic crisis and concomitant takotsubo cardiomyopathy: a case report" pot

... ventricular dysfunction in the absence of coronary arterydisease.Case presentation: We report a unique case of a 60-year-old Hispanic woman with myasthenia gravis whodeveloped takotsubo cardiomyopathy ... patient’sneuromuscular condition and management and was a major contributor inwriting the manuscript. JTW analyzed and interpreted the patient’s data andwas a major contributor in writing the ... triggering of both takotsubo cardiomyopathy andmyasthenic crisis by the physiologic consequences of a state of severe emotional stress. We hypothesize that the mechanism underlying the rare association...

Báo cáo khoa học: " Air embolism as a cause of the systemic inflammatory response syndrome: a case report" pps

... regular and nomurmurs were heard. The patient was orally intubated andplaced on mechanical ventilation. A diagnosis of venous airembolism was made and the patient was taken to a hyper-baric ... andfollowing cardiopulmonary bypass [2–4]. We describe a case of SIRS associated with air embolism following the removal of a central line catheter.Case presentation A 65-year-old male with adult immune ... embolism the patient’s hemodynamic and clini-cal condition (elevated cardiac output, decreased systemicvascular resistance, tachypnea, fever and diffuse intravascularcoagulation) was compatible...

Tài liệu Báo cáo khoa học: Pharmacologic chaperoning as a strategy to treat Gaucher disease ppt

... increases the lysosomal concentration of partially active GC vari-ants, as demonstrated by increased cellular GC activity,an increased concentration of lysosomal GC glyco-forms and increased ... colocalization of GC with the lyso-somal markers based on ﬂuorescence microscopyanalysis.All of the GC variants that are amenable to phar-macologic chaperoning harbor mutations in the active-site ... the balance between substratesynthesis and degradation in the lysosome, inhibition of glucosylceramide biosynthesis may improve the clinicalcourse of disease. ZavescaÒ (Actelion Pharmaceuticals,South...

Tài liệu Báo cáo khoa học: Phage-display as a tool for quantifying protein stability determinants pptx

... laboratoryinvestigating the effect of mutations on the stability of the B1 domain of Streptococcal protein G (GB1). One aspect of GB1 stability that we have addressed is the tolerance formutations in the ... biophysical data can be obtained from a statistical analysis of selected phage populations [16]. We also discuss experiments addressing the physical basis of thisselection and the range of stabilities ... a phage selection.Design of a heavy chain antibody scaffold A conceptually similar approach was employed by Bondet al. in the design of a camelid heavy chain antibodyscaffold for use in constructing...

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