Báo cáo khoa học: "Antithrombin in sepsis revisited" docx

... needs prospective confirmation in a properly designed randomized controlled clinical trial. The odds of finding a successful result by administering antithrombin to patients with severe sepsis in such a trial ... treatment benefit. This finding is very reminiscent of data from the phase III Prowess trial of recombinant human activated protein C in patients with severe sepsis showing...

Ngày tải lên: 12/08/2014, 23:20

... noted that LPS in blood binds to LPS binding protein [5], activating the cell surface CD14 receptor [6]. This stimulates the release of a cascade of proinflammatory cytokines, including tumor necrosis ... against lethal endotoxemia and severe Gram-negative infections. Indeed, infusion of HDL blocked LPS-induced cytokine production in rabbits [11] and protected against lethal doses of endo...

Ngày tải lên: 12/08/2014, 20:20

... important denominator of clinical outcome. DIC has been shown to be a strong and independent predictor of mortality in patients with sepsis and severe trauma. Clinical studies aimed at intervening in the coagulation ... of coagulation activation in patients with severe sepsis that were included in the PROWESS trial, the pivotal phase III clinical trial of recombinant activated pro...

Ngày tải lên: 12/08/2014, 20:20

... specialized to a domain by inheriting and instantiating domain-specific types and instances of the PS objects. 5.3 Adaptive Turn Planning The fission component comprises detailed con- tent planning, media ... the multi-modal setting. Novel aspects in turn planning and realization include the comprehensive modeling in a sin- gle, OWL-based ontology and an extended range of context-sensitive...

Ngày tải lên: 20/02/2014, 12:20

... specified in the second and third rules in order to eliminate the need for ordering. In our account, we can define this alternation declaratively and succinctly. As with the coda voicing alternation ... Abstract In this paper we present a means of defin- ing morphonological phenomena in an in- heritance based lexicon. We make use of the theory behind the formal language MO...

Ngày tải lên: 09/03/2014, 01:20

... Formulae expressing these conditions on argumentation will only appear in sentences containing this kind of connectives, since I haven't found, as yet, simple sentences imposing conditions ... Implicature", in Syntax and Semantics, vol.11, Oh and Dinnen, eds. New York 1979. Montague, Richard : "The Proper Treatment of Quantification in Ordinary English" (197...

Ngày tải lên: 17/03/2014, 19:21

... nvasion in int estine of C orn Snake (Elaphe guttata). Figure 6 Cyclospora sp. invasion in intestine of Platyceps karelini - pathoanatomical changes. Figure 7 Cyclospora sp. invasion in intestine ... role in maintaining a rickettsial reservoir (Borr elia burgdorferi [15], Cowdria ruminantium [16], Coxiella burnetti) [13], while mosquitoes can play a role in maintaining the West Nile...

Ngày tải lên: 12/08/2014, 18:22

... on hypercoagulability in sepsis clearly seems to be interesting and important. In a recent issue of Critical Care, Gonano and co-workers [1] analyzed hypercoagulability in a subset of patients in the KyberSept ... to interfere with the clotting process at various sites [2]. AT activity is decreased in patients with trauma, shock and sepsis by virtue of its consumption during com...

Ngày tải lên: 13/08/2014, 03:20

... pleural involvement (gray line: visceral pleura intact, black line: visceral pleura invaded)Figure 1 Survival depending n visceral pleural involvement (gray line: visceral pleura intact, black line: ... occurred in 27/35(77.1%) pts. in the stage IIIA and in 21/40(52.5) pts in the stage IIB. In none of four pts. in the stage IIA cancer relapse occurred, unlike 22.2% pts. with relap...

Ngày tải lên: 09/08/2014, 04:21

... yields a sepsis incidence of 1.49 cases/1000 inhabitants in the year 1999. In total, 3517 patients (52.8%) had this as their main diagnosis, and 2121 patients (31.8%) had severe sepsis (sepsis ... code indicating acute organ dysfunction). In the latter group septic shock was the largest subgroup, including 1562 patients. Mean age and mortality in different subgroups are shown in...

Ngày tải lên: 12/08/2014, 20:20