Báo cáo khoa học: "Impact of HIV/AIDS on care and outcomes of severe sepsis" pdf

Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx

... 2010 The Authors Journal compilation ª 2010 FEBS P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity Anja ... sensitized them to the toxicity of extracellular dopamine. Neuronal expression of p25a thusholds the potential to sensitize the cells toward dopamine and toxinscarried by the dopamine transporter. Structured ... with 1% Triton X-100 and 1% SDS to ABFig. 4. p25a binds to porcine brain vesicles. (A) The wild-type and deletion constructs of p25a p25aDN, p25aDC and the p25a core, corre-sponding to residues...

Tài liệu Báo cáo khoa học: The elusive intermediate on the folding pathway of the prion protein pptx

... intermediate species on the folding pathway of PrP. The potential role of this intermediate in prion conversion is discussed.AbbreviationsPrP, prion protein; SHaPrP, Syrian hamster prion protein. FEBS ... indicative of the existence of stable, partially folded intermediates on the folding pathway of a protein [27–30]. The presence of an intermediate on the folding path-way of PrP was further disclosed ... conformational transition of the prion protein from its cellular state to the altered dis-ease-associated form [12]. Thus, an understanding of the folding and refolding mechanisms of the prion...

Tài liệu Báo cáo khoa học: Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores pdf

... SD Bax- a5 Buffer 23 6 15 2 10 2 7 1 19 4 26 320% TFE 62 5 26 2 0 1 0 1 3 1 9 6 60% TFE 61 5 27 2 0 1 0 2 1 1 11 5 0 .5 mM SDS 63 6 19 3 1 2 0 1 4 4 13 44mM SDS 61 4 25 3 0 1 0 1 4 2 10 6 Bax- a6 ... C 50 (lM)1) Bax- a5 Bax- a6PtdCho 158 .7 35. 2PtdCho:PtdSer ( 75 : 25) 59 .3 15. 8PtdCho:PtdSer (50 : 50 ) 37 .6 13.8PtdCho:CL (90 : 10) 35. 3 5. 7PtdCho:lysoPtdCho ( 95 : 5) 2 15. 1 53 .1PtdCho:lysoPtdCho ... Journal 273 (20 06) 971981 ê 20 06 The Authors Journal compilation ê 20 06 FEBS 973 Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores Ana J. Garcı´a-Sa´ez1,...

Tài liệu Báo cáo khoa học: Arginine ethylester prevents thermal inactivation and aggregation of lysozyme pptx

... equation and determined the apparent Tm.Results Thermal inactivation and aggregation of lysozyme in the presence of additivesFigure 1 s hows the thermal inactivation and aggregation of lysozyme ... presence of NaCl suggest that themolecular mechanism of ArgEE in preventing thermal inactivation and aggregation is different from that of Arg. Thermal unfolding proﬁle of proteins in the presence of ... Arginine ethylester prevents thermal inactivation and aggregation of lysozyme Kentaro Shiraki1, Motonori Kudou1, Shingo Nishikori1,2, Harue Kitagawa1,2, Tadayuki Imanaka3 and Masahiro...

Tài liệu Báo cáo khoa học: The undecided serpin The ins and outs of plasminogen activator inhibitor type 2 pdf

... Studies on the plasminogen activating system.J Biol Chem 26 7, 122 20– 122 26.85 Maurer F & Medcalf RL (1996) Plasminogen activator inhibitor type 2 gene induction by tumor necrosis factor and phorbol ... overexpression of plasminogen activator inhibitor type- 2. J Biol Chem 26 6, 20 960 20 964.63 Dickinson JL, Bates EJ, Ferrante A & Antalis TM(1995) Plasminogen activator inhibitor type 2 inhibitstumor ... encode the secreted and cyto-solic forms of plasminogen activators inhibitor 2. EMBO J 8, 328 7– 329 4. 12 von Heijne G, Liljestrom P, Mikus P, Andersson H &Ny T (1991) The efﬁciency of the uncleaved...

Tài liệu Báo cáo khoa học: A role for the intersubunit disulﬁdes of seminal RNase in the mechanism of its antitumor action docx

... A role for the intersubunit disulﬁdes of seminal RNase in the mechanism of its antitumor action Aurora Bracale1,*, Francesco Castaldi1,*, Lucio Nitsch2and Giuseppe D’Alessio11Dipartimento ... proposed for the mechanism of antitumour action of BS -RNase is based on the ability of the proteinto resist the neutralizing action of the cytosolic RNase inhibitor, a resistance due to the dimeric ... sulfhydryls.These results indicate that the intersubunit disulﬁde bonds of BS -RNase have a key role in the mechanism of antitumour action of the enzyme.Materials and methodsMaterialsIodoacetic acid...

Báo cáo khoa học: Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein doc

... hydantoinase, allantoinase and dihydrooratase [32]. Cyclic amidohydrolases share a number of physicochemical characteristics. Thesecharacteristics include quaternary, tertiary, secondary and ... decarboxyl-ation of OHCU to (S)-allantoin. Thus, the pathway of the conversion of uric acid to (S)-allantoin via the threeenzymes uricase, TLP (5-HIUase) and OHCU decar-boxylase was revealed ... 0Loktanella vestfoldensis SKA53 Proteobacteria, Alphaproteobacteria 2 0Roseovarius sp. HTCC2601 Proteobacteria, Alphaproteobacteria 2 0Ralstonia eutropha H16 Proteobacteria, Betaproteobacteria...

Báo cáo khoa học: " Dose-Incidence Relationships on the Prenatal Effects of Gamma-Radiation in Mice" pdf

... 7-11ABSTRACT2) The objective of this investigation was to evaluate dose-incidence relationships on the prenatal effects of gamma-radiation. Pregnant ICR mice were exposed on day 11.5 after conception, coincident ... length was measured from the tip of the snouttothebaseofthetail.Thelongitudinaldistancefromthetipofthesnouttothebaseoftheskullwasrecordedas head length. The distance between the two ears wasrecorded ... Relationships on the Prenatal Effects of Gamma-RadiationinMice 9Discussion The present work is the systematic study of dose-incidence relationships to acute irradiation, assessed bydetectable effect in...

báo cáo khoa học: "A cytogenetic investigation on peripheral blood lymphocytes of cattle affected by enzootic bovine leukemia" pdf

... A cytogenetic investigation on peripheral blood lymphocytes of cattle affected by enzootic bovine leukemiaA. GALLIL. CARBONIA. GHIDONI ** Consorzio Provinciale Fecondazione ... effects of the consequentstimulation on other subsets of B -lymphocytes, as suggested by Kx!sTErrsErr et al.(1982). Until this point is made clear, the analysis of cytogenetic ... subjects affected by enzootic bovine leukemia with lymphocytosis, whose lymphocyte cultures were stimulated by concanavalin A.Key words : Chromosome, enzootic bovine leukemia,...

báo cáo khoa học: "Phagocytic response to fully controlled plural stimulation of antigens on macrophage using on-chip microcultivation system" docx

... purposes)Journal of NanobiotechnologyOpen AccessShort CommunicationPhagocytic response to fully controlled plural stimulation of antigens on macrophage using on- chip microcultivation systemKazunori ... secondphagocytic process of the macrophage depending on thetiming of the second stimulation. If the second antigen stimulation started within 10 s of the first stimulation, the response of ... Corresponding author Abstract To understand the control mechanism of innate immune response in macrophages, a series of phagocytic responses to plural stimulation of antigens on identical cells was...

báo cáo khoa học: " Translating global recommendations on HIV and infant feeding to the local context: the development of culturally sensitive counselling tools in the Kilimanjaro Region, Tanzania" doc

... AccessResearch article Translating global recommendations on HIV and infant feeding to the local context: the development of culturally sensitive counselling tools in the Kilimanjaro Region, TanzaniaSebalda ... and infant feeding and related generic counselling tools to the local social and cultural context of infant feeding and HIV in the Kilimanjaro Region of northern Tanzania. Because infant feeding practices ... information exchange related to infant feeding in the context of HIV counselling and testing. Development of performance and learning objectives and key messagesFollowing dissemination of findings and...

báo cáo khoa học: " Impact: a case study examining the closure of a large urban fixed site needle exchange in Canada" ppt

... reproduc-tion in any medium, provided the original work is properly cited. Case study Impact: a case study examining the closure of a large urban fixed site needle exchange in CanadaJoan MacNeil*† and ... this article as: MacNeil and Pauly, Impact: a case study examining the closure of a large urban fixed site needle exchange in Canada Harm Reduc-tion Journal 2010, 7:11Received: 7 August 2009 Accepted: ... 7:11http://www.harmreductionjournal.com/content/7/1/11Page 2 of 8 the single fixed site needle exchange in a large urban cen-ter. Thus, the unit of analysis or case, is the closure of the fixed site needle exchange. We have used a chronologicalapproach...

báo cáo khoa học: " Toward a treaty on safety and cost-effectiveness of pharmaceuticals and medical devices: enhancing an endangered global public good" pot

... for citation purposes)Globalization and HealthOpen AccessDebate Toward a treaty on safety and cost-effectiveness of pharmaceuticals and medical devices: enhancing an endangered global public ... medicinesthat Australians need, at a cost individuals and the com-munity can afford; medicines meeting appropriate stand-ards of quality, safety and efficacy; quality use of medicines; and maintaining ... Globalization and Health 2006, 2:5 http://www.globalizationandhealth.com/content/2/1/5Page 8 of 9(page number not for citation purposes)in bilateral trade deals) as a rational and scientific...

báo cáo khoa học: " Some historical remarks on the conservative treatment of facial paralysis – comment on ''''Temporary ectropion therapy by adhesive taping: a case study''''" pot

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Báo cáo khoa học: "Recently published papers: the Jekyll and Hyde of oxygen, neuromuscular blockade and good vibrations" doc

... paucity of evidence tosupport prophylactic chest physiotherapy after abdominalsurgery [15] and other previous negative reviews [16,17].Tsuruta and colleagues report the safety and efficacy of superimposing ... clinicalconsequences of altering the pro-inflammatory cytokineprofile, especially on the incidence of extra-pulmonary organdysfunction, nor indeed am I aware of any evidence tosupport the hypothesis that ... ARDS.Cue the rhythm section?December saw the publication of three papers investigating the therapeutic potential of intermittent intrapulmonarypercussive ventilation (IPV). This technique, and the...

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