Báo cáo khoa học: " Science review: Carnitine in the treatment of valproic acid-induced toxicity – what is the evidence" pot

... formed; this step is needed because the inner mitochondrial membrane is not permeable to acylcarnitines. Valproylcarnitine is then exchanged for free carnitine by carnitine translocase. In the mitochondrial ... neonates develop carnitine deficiency because of impaired proximal renal tubule carnitine reabsorption and immature carnitine biosynthesis. The final step in...

Ngày tải lên: 12/08/2014, 22:22

... continuous with the sinuses of the medulla, which drain into the central vein of the medulla. The right adrenal vein drains into the inferior vena cava and the left into the renal vein. Hence, the ... ACTH/cortisol synthesis. In normal individuals administration of an opiate agonist results in a fall in plasma cortisol levels, although it induces hypotension. In...

Ngày tải lên: 12/08/2014, 20:20

... hormones, numbered by their amino acid sequences beginning at the N-terminal end of the ANP prohormone, consist of the first 30 amino acids of the prohormone (i.e. proANP 1–3 0; long-acting natriuretic peptide), ... results should be interpreted cautiously because of the relatively small number of patients included, the finding of a lack of value for prediction of...

Ngày tải lên: 12/08/2014, 20:20

... hypothesis’ and the ‘epithelial hypothesis’. The former hypothesis suggests that neutrophil apoptosis plays an important role in the resolution of inflamma- tion, and predicts that inhibition of neutrophil ... apoptosis are susceptible to therapeutic intervention. In the present review we examine two important hypotheses that link apoptosis with the pathogenesis of acute l...

Ngày tải lên: 12/08/2014, 19:22

... bound to proteins. The two main binding proteins are the cortisol-binding globulin (CBG) and albumin [1]. Review Clinical review: Corticotherapy in sepsis Helene Prigent 1 , Virginie Maxime 2 and ... progress in our understanding of the role played by the hypothalamic–pituitary– adrenal axis in the response to sepsis, and of the mechanisms of action of glucocortico...

Ngày tải lên: 12/08/2014, 19:22

... in the lung in ALI decreases the capacity of the epithelium to remove edema fluid from the distal airspaces of the lung. Disruption of the integrity of the alveolar–capillary membrane results in ... clearance, they are anti-inflammatory, and they induce bronchodilation. The preclinical studies of the effects of beta-2 adrenergic agonists in models of AL...

Ngày tải lên: 12/08/2014, 20:20

... influ- ential interaction between the interviewer and the inter- viewed during the interviews that could influence the statements of the interviewed e.g., the use of leading ques- tions. In the phase of ... between the recording of metritis scores and veterinarians' decision making connected to metritis treat- ment and potential links to data quality. This under...

Ngày tải lên: 25/10/2012, 10:45

Ngày tải lên: 21/02/2014, 20:20

... tagged training corpus and upgrading or downgrading likelihoods according to the probability markets against word tags in the lexicon or suffixlist. In the majority of cases, this first order ... the intermediate tag is misleading. The curreat vemm of the CLAWS system requires no pro- editing and auribums the correct won1 tag to over 96 per cent of the input r...

Ngày tải lên: 08/03/2014, 18:20

... b-1,3-glucan polymers. The nature of the aromatic residues in the two triads might then be reflecting the different func- tional constraints for the two proteins: Exg requiring precise positioning of laminarin substrate ... subfamilies [15]. The stacking of aromatic residues against the hydrophobic faces of sugar rings is a recurring feature of protein–carbohy- drat...

Ngày tải lên: 15/03/2014, 23:20