Báo cáo khoa học: "The role of thyroid hormone therapy in acutely ill cardiac patients" pot

... rekindled interest in the use of thyroid hormone therapy in critical illness. Continued improvements in survival after critical cardiac illness provokes the question of whether thyroid hormone therapy ... of thyroid hormone therapy in acutely ill cardiac patients Kathleen L Wyne Assistant Professor, Division of Endocrinology and Metabolism, Department...

Ngày tải lên: 12/08/2014, 22:22

... clear whether or not H39 is dominantly tuning the V H ⁄ V L interaction of other Fvs, including HyHEL-10. In addition, the effect of the H39 mutation on antigen binding has not yet been analyzed. ... improved the antigen-binding affinity of Fv, similarly to the level of scFv (Table 2). Some single V H domains of anti-protein IgG, inclu- ding HyHEL-10 and D1.3, were known to retain...

Ngày tải lên: 07/03/2014, 12:20

... Cardie, Vincent Ng, David Pierce,Chris Buckley. Ex- amining the role of statistical and linguistic knowledge sources in a general-knowledge que stion answering sys- tem. In Proceedings of the 6th ... resolution. In the following example, a chain of coreference links Bill Gates and Mi- crosoft founder in the candidate answer: Answer Question Q318: Where did Bill Gates go to col...

Ngày tải lên: 08/03/2014, 05:20

... glu- cokinase and hexokinase I in distinct pools [3,24], or by the involvement of mechanisms, additional to Glc6P, in mediating the effects of glucokinase over- expression. As glucokinase binds ... the increase of Glc6P in the presence of S4048 was caused by the inhibition of Glc6P hydro- lysis in the absence of detectable changes in glucose phosphorylation. S4048 causes...

Ngày tải lên: 16/03/2014, 14:20

... tight binding affinity was demonstrated towards lauric acid, resulting in the synthesis of mainly x-1 hydroxylated lauric acid, suggesting a role in the lipid oxidative metabolism. Interestingly, ... mem- ber of subfamily A of family 94 (there is more about the activity of this enzyme in the accompanying mini- review by Pinot & Beisson [4]). Over 11 000 P450 genes are inclu...

Ngày tải lên: 22/03/2014, 16:21

... Nuijens Pharming, Archimedesweg, Leiden, the Netherlands Lactoferrin (LF) is an iron-binding glycoprotein of the innate host defence system. To elucidate the role of N-linked glycosylation in protection of ... Properties of the iron-binding site of the N-terminal lobe of human and bovine lactotransferrins. Importance of the glycan moiety and of the non–covalent interaction...

Ngày tải lên: 30/03/2014, 13:20

... study in which overexpression of ADAM10 in HEK293 cells increased the a-secretase cleavage of APP, while expression of a dominant negative form of ADAM10 with a point mutation in the zinc binding ... ADAM10 and TACE are not critically involved in the shedding of ACE. APMA has been reported to induce the shedding of a number of protein ectodomains, including APP, from CHO...

Ngày tải lên: 30/03/2014, 14:20

... to fulfill the chilling requirement to break winter dormancy in Scots pine has been stressed (e.g., Wareing, 1951; Vegis, 1965; Sarvas, 1974). In the following, I will use ... however. Ins- tead the plants formed more stem units. The role of photoperiod and temperature in the induction and the release of dormancy in Pinus sylvestris L. s...

Ngày tải lên: 09/08/2014, 02:21

... the role of adjuvant pelvic RT in rec- tal cancer with synchronous liver metastasis has not been defined. In this study, we investigated the clinical implications of adjuvant pelvic RT following ... Stone MD: The role of surgical resection of liver metastases in colorectal carcinoma. Seminars in oncology 1991, 18:399-406. 3. August DA, Ottow RT, Sugarbaker PH: Clinical per...

Ngày tải lên: 09/08/2014, 09:20

... Amplification of MYCN was confirmed to be a strong predictor of adverse outcome, but other single genomic alterations, such as loss of 11q or gain of 17q, were overridden by the presence of any kind of ... limited by the instability of mRNA in comparison with DNA, which will require strict adherence to elaborated standard operating procedures in the processing of tum...

Ngày tải lên: 11/08/2014, 12:20