Báo cáo khoa học: "Drotrecogin alfa (activated) in patients with severe sepsis presenting with purpura fulminans, meningitis, or meningococcal disease: a retrospective analysis of patients enrolled in recent clinical studies" ppt
Báo cáo khoa học: "Drotrecogin alfa (activated) in patients with severe sepsis presenting with purpura fulminans, meningitis, or meningococcal disease: a retrospective analysis of patients enrolled in recent clinical studies" ppt
... Indianapolis, IN, USA
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Clinical Development Associate, Lilly Research Laboratories, Indianapolis, IN, USA
8
Associate Global Medical Information Consultant, Lilly Research Laboratories, Indianapolis, IN, ... http://ccforum.com/content/9/4/R331
R331
Vol 9 No 4
Research
Drotrecogin alfa (activated) in patients with severe sepsis
presenting with purpura fulminans,...
Báo cáo khoa học: "Drotrecogin alfa (activated): down and not out, but not really in eithe" ppt
... that a
meta -analysis using individual patient data and adjusting for
baseline covariates would be an important first step to identify
appropriate patients for DrotAA. However, such an analysis
would ... selecting a more uniform subgroup
of patients with severe sepsis and a high risk of death. In
particular, for the subgroup with an APACHE II score of 25 or
more...
Báo cáo khoa học: "Drotrecogin alfa (activated) should not be used in patients with severe sepsis and low risk for death" pdf
... the Administration of Drotrecogin Alfa (Activated) in Early
Stage Severe Sepsis (ADDRESS) study [1], Abraham and
colleagues assessed the role of DrotAA in patients with
severe sepsis and low ... complete a number of phase IV studies evaluating the
use of DrotAA in lower-risk patients with severe sepsis, in
children with severe sepsis, and i...
Báo cáo khoa học: "Drotrecogin alfa (activated): current evidence supports treatment for severe sepsis patients with a high risk of death" ppsx
... 344:699-709.
3. Abraham E, Laterre PF, Garg R, Levy H, Talwar D, Trzaskoma BL,
Francois B, Guy JS, Bruckmann M, Rea-Neto A, et al., for the
Administration of Drotrecogin alfa (activated) in Early Stage
Severe ... estimate
to the left of the line of identity (1) favors treatment with Drotrecogin alfa (activated) and an estimate to the right favors placebo. A 95% conf...
Báo cáo khoa học: "Drotrecogin alfa (recombinant human activated protein C) in severe acute pancreatitis" pptx
... pharmacologic intervention for acute
pancreatitis. Death from acute pancreatitis remains a major issue,
and late deaths are often related to haemorrhage and are
associated with unresolved intra-abdominal ... intra-abdominal sepsis. Drotrecogin
alfa, an analogue of endogenous protein C, has antithrombotic,
anti-inflammatory and profibrinolytic properties, and it has been
shown to reduc...
Báo cáo y học: "Drotrecogin alfa (activated) may attenuate severe sepsis-associated encephalopathy in clinical septic shock" pot
... levels in DrotAA-treated patients; °P < 0.05 DrotAA-treated vs. -
untreated patients. Values are means ± SEM DrotAA: drotrecogin alfa
(activated); GCS: Glasgow Coma Scale; SEM: standard error of ... present
in more severe encephalopathy and does not affect
mortality.
Abbreviations
APACHE: Acute Physiology and Chronic Health Evaluation; APC: activated pro-
tein C; DrotAA: Dro...
Báo cáo y học: "Drotrecogin alfa (activated): real-life use and outcomes for the UK" ppt
... Sablotzki A, Arkins N, Utterback BG, Macias WL, Adminis-
tration of Drotrecogin Alfa (Activated) in Early Stage Severe Sepsis
(ADDRESS) Study Group: Drotrecogin alfa (activated) for
adults with ... ICNARC physiology scores and for patients
with two organs failing, as compared with a significant reduc-
tion in mortality for higher scores and for patients wit...
Báo cáo khoa học: Cause of mortality in insects under severe stress Hitoshi Matsumoto, Kohjiro Tanaka, Hirofumi Noguchi and Yoichi Hayakawa pdf
... the
neurilemma and perineural cells is visible in
MPLI-injected larval brain (as indicated in D
with an arrow).
Fig. 2. [
3
H]Dopamine incorporation into MPLI-treated larval brains.
Brains were dissected ... times
more abundant than that observed in control larvae.
Structural changes in MPLI-treated larval brains
The dopamine in ux into the MPLI-injected larval brain
suggested that...
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