... FEBSsion of SREBP-1 in the brain does increase in miceduring aging [39], a phenomenon also observed in theperipheral nerve [3]. The meaning of this aging-relatedincrease in SREBP-1 in both the PNS ... myelin protein-22, myelin asso-ciated glycoprotein (MAG) and myelin basic protein,but no myelin-specific lipids. Nevertheless, whereas allmajor lipid classes are present in myelin, as in othermembranes, ... transit of albumin,a fatty acid-binding protein present in the developingbrain, into the astrocytic endoplasmic reticulumcompartment. This transit of albumin correlated withinduction of SREBP-1...