intensive replacement of basal insulin in
intensive replacement of basal insulin in
... 2003 W hen rapid-acting insulin analogs are used in type 1 diabetic pa- tients as mealtime insulin in place of human regular insulin, intensifi- cation of replacement of basal insulin is needed to ... mealtime or basal insulin dose. In contrast, with glargine there was a de- crease in mealtime insulin lispro and an increase in basal insulin requirements. Th...
Ngày tải lên: 12/08/2014, 20:59
Báo cáo y học: "Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/ cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma"
... morn- ing [21-24], being consistent with the findings of this study. However, in the NDP group, the pattern of circadian rhythm in 5-FU pharmacokinetics was cer- tainly different from that in ... but when using NDP instead of CDDP, it is necessary to look for some marker capable of indicating clinical re- sponse. In conclusion, only a small number of patients were enrol...
Ngày tải lên: 26/10/2012, 09:53
Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx
... triglyceride, glucose, leptin and insulin, and insulin sensitivity, in TG mice After 6 weeks of normal or HF diet, serum levels of triglyceride, glucose, leptin and insulin were deter- mined (Fig. 4A). ... improvement in peripheral insulin resis- tance through the activation of PPARc in WAT, it is possible that PGD 2 stimulates pancreatic islets to increase insulin secret...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx
... The binding of ZIP to Grb14, by recruiting protein kinase Cf, enhances the serine phos- phorylation of Grb14 and its inhibitory effect on IR kinase and insulin signaling [10]. The interaction of Grb14 ... livers of rats studied at the indicated time points (one rat per time point) after injection of 30 lg of [GluA13,GluB10 ]insulin (A3), [HisA8,HisB4,GluB10,HisB27 ]insulin (H2...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khoa học: Insulin-dependent phosphorylation of DPP IV in liver Evidence for a role of compartmentalized c-Src ppt
... proteinase K. DPP IV levels following stimulation with insulin and bpV(phen) In order to examine changes in DPP IV levels follow- ing insulin stimulation, rats were injected with the PTP inhibitor ... Identification, by finger printing MS, of the nine major proteins purified by anti-PY affinity column chromatography, stained with Coomassie blue, indicates that of these proteins, four...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: Insights into the interaction of human arginase II with substrate and manganese ions by site-directed mutagenesis and kinetic studies Alteration of substrate specificity by replacement of Asn149 with Asp docx
... by agmatine hydrolysis, in studying the inhibitory effect of agmatine on arginine hydrolysis, reactions were followed by measuring the formation of ornithine, determined by the method of Chinard ... agmatine in E. coli agmatinase and l-arginine in B. caldovelox arginase [37], indicating that the substrate specificity of these enzymes rely mainly in substituents at C-a. This has...
Ngày tải lên: 20/02/2014, 02:21
Báo cáo khoa học: Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity docx
... enzyme. Binding of oxidized FMN to the mutant proteins To characterize the serine mutant proteins in further detail, binding of the oxidized FMN cofactor to the isolated apoproteins was investigated ... double-mutant protein, in contrast to the single-mutant proteins (Ser16Ala and Ser127Ala) is not capable of forming the flavin-derived intermedi- ate. The decay rate of the intermed...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Choline increases serum insulin in rat when injected intraperitoneally and augments basal and stimulated aceylcholine release from the rat minced pancreas in vitro pptx
... choline-induced increase in insulin (Table 1). Effects of relatively selective antagonists of muscarinic receptors on choline-induced increases in serum insulin To determine the involvement of muscarinic ... Turkey Intraperitoneal injection of choline (30–90 mgÆkg )1 ) produced a dose-dependent increase in serum insulin, glu- cose and choline levels in rats. The increase...
Ngày tải lên: 17/03/2014, 09:20
Báo cáo khoa học: Role of peroxidase inhibition by insulin in the bovine thyroid cell proliferation mechanism pdf
... decrease of thyroid hormone biosynthesis in primary cultures in the presence of insulin. In addition, our data suggest that insulin stimulates cell division, in bovine thyroid cultures, promoting ... monolayer primary cultures of bovine thyroid cells, maintained in the presence of insulin, produced a cytosolic inhibitor of TPO activity. Its molecular mass of less tha...
Ngày tải lên: 30/03/2014, 14:20
