Báo cáo y học: "Scanning the horizon: emerging hospital-wide technologies and their impact on critical care" pot

... ofCommentaryScanning the horizon: emerging hospital-wide technologies and their impact on critical careGanesh Suntharalingam1, Jonathan Cousins2, David Gattas3 and Martin Chapman41Consultant ... developed national horizon scanning systemsto identify and monitor new health technologies. There isvariation in how these centres gather information, but aconsistent set of high priority sources ... driving their local and national healtheconomy.ConclusionA variety of emerging technologies are examined here. Veryfew of these are designed or marketed to be specific tointensive care, and...

Báo cáo y học: "Targeting the interleukin-15/interleukin-15 receptor system in inflammatory autoimmune diseases" pot

... & Therapy Vol 6 No 4 WaldmannIntroductionCytokines are crucially involved in the regulation of the normal human immune response. Furthermore, dysregula-tion of cytokine expression also ... distinct and at times contrastingcontributions to the life and death of lymphocytes,especially in adaptive immune responses [13].CommentaryTargeting the interleukin-15/interleukin-15 receptor system ... by the retrovirus HTLV-I.Through the action of the HTLV-I-encoded Tax proteinthere was transactivation of the genes encoding IL-15 and IL-15Rα [6]. The interaction of the expressed IL-15 and...

Báo cáo y học: "Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis" pps

... performed the Affymetrix chip analysis. US, NS and CP analysed the MMP, cathepsin and cytokine expres-sion by real-time PCR. MH performed the zymography, the MMP activity assay and the cytokine ... activity and proteinase inhibitor expression at the mRNA level and, on the other, cytokine expression. The mRNA data were manifested at the protein level by zymog-raphy and activity assays. Safranin ... rea-son for the decreased expression of MMP-3 on day 7 at the mRNA level in our study. The biological activity of the proteinases can be regulatedtranscriptionally and post-transcriptionally by...

Báo cáo y học: " Disrupting the rhythm of depression: design and protocol of a randomized controlled trial on preventing relapse using brief cognitive therapy with or without antidepressants" pptx

... of Psychology at the Universityof Groningen in collaboration with psychologists of the Rotterdam University and Maastricht University and psychiatrists of the departments of Psychiatry of the University ... the patient through their therapist: if a therapist wants toinform the patient themselves, the patient thenreceives the information via the therapist and i s givena letter containing all the ... the trial. If they agree to enter the trial, they complete acopy of the consent form and send it back to the researcher. The second procedure we use is by direc tly informing the patient in case the patient...

Báo cáo y học: "DeDefining the relationship between gastroesophageal reflux and cough: probabilities, possibilities and limitations" ppt

... disparity of opinion between respiratory and gastroenterology society guidelines on the link between GORD and chronic cough. This commentary explores of these issues.Background The first guideline on ... upper airway symp-toms to GORD [6-9,29], adult respiratory ones largelyendorse the cause and effect [5,30]. Recent gastroenterol-ogy society recommendations are based largely on system-atic ... production. The spectrum and fre-quency of causes, key components of the diagnostic evalua-tion, and outcome of specific therapy. Chest 1995, 108:991-997.34. Katz PO, Castell DO: Medical therapy...

Báo cáo y học: "Assessing the effects of multiple infections and long latency in the dynamics of tuberculosis" ppt

... 1), the solutions of the polynomialQy()given by equation (B.7), as a function of the transmission coefficient b .The curve on the right (labelled 1) corresponds to the case g <g+ and ... for10c<<there are two positive solutions for the equation (B.7), whichwill be denoted as y 1+ and y 1−, respectively, the large and the small roots. The la rgeroot y 1+is monotonically increasing ... years-1(b > b0), we have onlyone attracting region and, independently of the initial conditions, the dynamical systemgoes to the asymptotic equilibrium P+(figure not shown). When the...

Báo cáo y học: "Feed the ICU patient ‘gastric’ first, and go post-pyloric only in case of failure" pptx

... contradictory studies and two non-con clusive meta-analyses, by randomly assigning the patients to either feeding method from the start.  ey (apparently) observed a lower daily energy deﬁ cit, ... early enteral feeding by gastric and post-pyloric routes, White and colleagues have shown that gastric feeding is possible and e cient in the vast majority of critically ill patients. But the ... group: the diﬀ erence between median APACHE II (Acute Physiology and Chronic Health Evaluation II) scores of 24.5 and 30 is clinically relevant. Furthermore, to have more diabetics in the PP...

Báo cáo y học: " Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts" pdf

... differencesof cytokine stimulations between patients carrying WTalleles and those carrying SNP alleles on day 7. The onlyprobable explanation may come from the known changesof responsiveness of monocytes ... in the Figure 2 Impact of TIRAP/Mal or TLR4 polymorphisms or their combinations on monocyte release of IL-6 and TNF-α following LPS-stimulation. Monocytes were isolated from patients on day ... groups the Kruskall-Wallis test, the Mann-Whitney U test or one-way analysis of variancewith a Bonferroni correction and within a group the Wil-coxon's rank sum test were used, respectively....

Báo cáo y học: "How the relationships between general practitioners and intensivists can be improved: the general practitioners'''' point of view" ppt

... end-of-lifedecisions, and conveying information to GPs at patientdischarge through a short hospitalization report includ-ing the reason for admission, the primary diagnosis, and the treatment. The impact ... Leger R, Xue X, Colacone A, Soucy N, Vandal A, Boivin JF, Unger B: Impact of a standardized communication system on continuity of care between family physicians and the emergency department. CJEM ... patient con-sultation). In another study, Long et al. [8] sent a ques-tionnaire to 80 consultants working for four hospitals insoutheast England and to 100 GPs in the same area. Only2% of the...

Báo cáo y học: "Exploring the transcriptional landscape of plant circadian rhythms using genome tiling arrays" potx

... ELONGATED HYPOCOTYL, and (d) EARLY FLOWERING3. The top half of each panel displays the Watson strand and the bottom half the Crick strand. Individual features that exceed the false discovery ... arrays each contain1,683,620 unique 25-mer oligonucleotide features. One arrayis composed of the forward or Watson strand and the other the reverse or Crick strand. The Arabidopsis InformationResource ... (At2g38325) and MIR390B (At5g58465) were reliably detected by the AtTILE1arrays, neither was found to exhibit a circadian rhythm (Addi-tional data files 1 and 2). On the other hand, the abundance ofthe...

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