Báo cáo y học: "Pro/con clinical debate: It is acceptable to stop large multicentre randomized controlled trials at interim analysis for futility" pptx
Báo cáo y học: "Pro/con clinical debate: It is acceptable to stop large multicentre randomized controlled trials at interim analysis for futility" pptx
... should ever be stopped for futility. Review Pro/con clinical debate: It is acceptable to stop large multicentre randomized controlled trials at interim analysis for futility David A Schoenfeld 1 and ... debate the role of futility-stopping rules. Keywords clinical research, futility, interim analysis, randomized controlled trials, stopping rules The...
Ngày tải lên: 12/08/2014, 20:20
Báo cáo y học: "Illustrating risk difference and number needed to treat from a randomized controlled trial of spinal manipulation for cervicogenic headach" ppsx
... that are not reflected in the odds ratio, a statistic often reported for binary data [5,7]. Clearly, binary analysis is appropriate with naturally dichotomous variables, such as cure or death. ... with missing data imputed [11]. Five subjects were eliminated from this analysis due to lack of follow-up after baseline. For this secondary analysis, the continuous outcomes were dicho...
Ngày tải lên: 13/08/2014, 14:20
Báo cáo Y học: Proteolytic action of duodenase is required to induce DNA synthesis in pulmonary artery fibroblasts A role for phosphoinositide 3-kinase pot
... PAR2. In summary, this study has demonstrated that duoden- ase induces DNA synthesis in pulmonary artery fibro- blasts and that this response may be mediated by an atypical PAR, either an i soform of ... duodenase is capable of cleaving certain substrates with trypsin-like primary specificity, we initially hypothesized that induction of DNA synthesis by duoden- ase is mediated through a PAR...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: "The acute management of trauma hemorrhage: a systematic review of randomized controlled trials" ppsx
... to be recruited Expected end date CRISTAL: Colloids versus crystalloids for resuscitation of critically ill patients ITU patients, fluid resuscitation Colloids Crystalloids 28 day mortality 3,010 ... Dentistry, Queen Mary University of London, London, E1 4NS, UK. Authors’ contributions NC contributed to study design, acquisition of data, analysis and interpretation of data, drafted an...
Ngày tải lên: 14/08/2014, 07:21
Báo cáo y học: "(Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis" ppsx
... Hydro- lysis of pyrophosphate, which is an inhibitor of hydro- xyapatite formation, is especially needed to facilitate normal mineralisation [99]. In vitro studies in VSMC’s showed that the ALP ... 16:64-70. 54. Yamada S, Inaba M, Goto H, Nagata-Sakurai M, Kumeda Y, Imanishi Y, Emoto M, Ishimura E, Nishizawa Y: Associations between physical activity, peripheral atherosclerosis and b...
Ngày tải lên: 12/08/2014, 15:22
Báo cáo y học: " Improving surgical outcomes: it is the destination not the journey" ppt
... hemodynamic optimization: relationship to methodological quality. Crit Care 2005, 9:771-779. 3. Abbas SM, Hill AG: Systematic review of the literature for the use of oesophageal Doppler monitor ... intraoperative therapy based on autocalibrated arterial pressure waveform analysis reduces hospital stay in high-risk surgical patients: a randomized, controlled trial. Crit Care 2010...
Ngày tải lên: 13/08/2014, 20:22
Báo cáo y học: "Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis" ppt
... negligi- Figure 4 In situ hybridization of ADAM15 in rheumatoid arthritis synovial tissuesIn situ hybridization of ADAM15 in rheumatoid arthritis synovial tissues. Paraffin sections were reacted with digoxigenin-labeled ... possibility that ADAM15 is involved in angiogenesis in RA synovium. Introduction In rheumatoid arthritis (RA), the affected joints develop chronic synovitis that is ch...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "An ethnobotanical survey of plants used to manage HIV/AIDS opportunistic infections in Katima Mulilo, Caprivi region, Namibia" ppt
... programmes discourage the use of traditional med- icines, fearing that the efficacy of antiretroviral drugs may be inhibited by traditional medicines, or that their interactions could lead to toxicity ... tra- ditional medicines can also lead to a discontinuation of ART therapy [33]. Thus many African governments including Namibia still have contradictory attitudes towards traditional med...
Ngày tải lên: 10/08/2014, 09:21
Báo cáo y học: "Treatment of eccrine porocarcinoma with metastasis to the parotid gland using intensity-modulated radiation therapy: a case report" pptx
... the treatment course. Discussion Eccrine porocarcinoma is challenging to diagnose based on clinical presentation alone, and histopathological examination is almost always required. Typically, a Figure ... parotidectomy with facial nerve preservation and cer- vical lymphadenectomy. Surgical pathology specimens revealed a moderately differentiated carcinoma with growth pattern and morph...
Ngày tải lên: 11/08/2014, 12:20
Báo cáo y học: " REFLEX, a social-cognitive group treatment to improve insight in schizophrenia: study protocol of a multi-center RCT" pptx
... Cognitive- behavioural therapy for refractory psychotic symptoms of schizophrenia resistant to atypical antipsychotic medication: Randomised controlled trial. British Journal of Psychiatry 2005, ... Leeuwarden. Patients who partici- pate in the fMRI study will be randomized separately. 3. Statistical analysis 3.1 Behavioral data Analysis will be performed according to the intent...
Ngày tải lên: 11/08/2014, 16:20