Báo cáo y học: "Variability science in intensive care – how relevant is it" docx
Báo cáo y học: "Variability science in intensive care – how relevant is it" docx
... variability in intensive care. The commentary discusses whyvariability can nevertheless accurately estimate prognosis and how easily this can be implemented in the critically ill.Keywords heart ... a marker of sympathetic activity in conditions ofCommentaryVariability science in intensive care – how relevant is it?P van de BorneDepartment of Cardiology, Erasme Hospital, Brussels, BelgiumCorrespondence: ... Research by Seely et al., see page 513AbstractThe article by Seely et al. in this issue of Critical Care highlights that variability portend prognosis.Numerous parameters interact to modify variability...
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Báo cáo y học: "Oropharyngeal decontamination in intensive care patients: less is not more" ppsx
... length of stay and, possibly,increased mortality in ICU patients. Colonization of the oropharyn-geal cavity with potentially pathogenic micro-organisms is instru-mental in the pathogenesis of VAP, ... was used in one study [13] and CHX was combined with Colistine in another [12], and in one study effects were compared tohistoric controls [10]. Moreover, all individual studies pub-lished so ... whichCommentaryOropharyngeal decontamination in intensive care patients: less is not moreLennie PG Derde1and Marc JM Bonten1,21Julius Center for Health Sciences and Primary Care, Heidelberglaan...
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Báo cáo y học: "Early tracheostomy in intensive care trauma patients improves resource utilization: a cohort study and literature review" pdf
... endotracheal intubation are increasingly being recog-nized, including injury to the larynx and trachea, and patientdiscomfort. In addition, endotracheal intubation often requiresthe administration ... hospital outcome. Adopting astandardized strategy of early tracheostomy in appropriately selected patients may help in reducingunnecessary resource utilization.Keywords: intensive care, mechanical ... Intensive Care Department (MC 1425), King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia3ICU Pulmonary Fellow, Intensive Care Department (MC 1425), King Abdulaziz Medical City, Riyadh,...
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Báo cáo y học: "Spontaneous hypothermia on intensive care unit admission is a predictor of unfavorable neurological outcome in patients after resuscitation: an observational cohort study" pptx
... Spontaneous hypothermia in combina-tion with coagulopathy and acidosis is therefore consid-ered as a lethal triad in trauma patients [5]. In septicpatients presenting with hypothermia, mortality is approximately ... [7].It is conceivable that body temperature on admissioncan be used as a sign of the ability of the body to maintaintemperature homeostasis. Under normal circumstances,body temperature is mainly ... [3,4]. In trauma patients, spontaneoushypothermia occurs in more severely injured patients andmight therefore be caused by disrupted homeostasis anddepletion of energy stores occurring during...
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Báo cáo y học: "Delirium epidemiology in critical care (DECCA): an international study" docx
... 1-day point-prevalence international study confirmsprevious findings from single-center studies showingthat delirium occurs frequently and is independentlyassociated with adverse outcomes in ... Epidemiology in Critical Care) Study GroupAbstractIntroduction: Delirium is a frequent source of morbidity in intensive care units (ICUs). Most data on itsepidemiology is from single-center ... beimplemented in the critical care setting.Finally, different patterns of pra ctice may play animportant role in criti cal care outcomes [23]. Currently,a paucity of data exists regarding global...
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Báo cáo y học: "The epidemiology of intensive care unit-acquired hyponatraemia and hypernatraemia in medical-surgical intensive care unit"
... assessedusing the APACHE II score and intensity of care using theTISS score [15,16].Patients were classified into three categories of admissiondiagnosis, based on data recorded by the admitting physician,medical, ... hyponatraemia and hypernatraemia arecommon in the critically ill. The risk of ICU-acquired sodiumdisturbances appear to vary according to patient characteris-tics. Finally, ICU-acquired hyponatraemia ... epidemiology of intensive care unit-acquired hyponatraemia and hypernatraemia in medical-surgical intensive care unitsHenry Thomas Stelfox1,2,3, Sofia B Ahmed3,4, Farah Khandwala5, David Zygun1,2,6,...
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Báo cáo y học: "Somatic mutations in mitochondria: the chicken or the egg" docx
... theetiology is simply unknown. Biomedical researchers haveinvestigated various aspects of this intricate disease. DaSylva and colleagues have now analyzed yet another piece in the ‘RA-puzzle’. In ... osteoarthritis (OA). Moreimportantly, in RA tissue significantly more of these mutationsresulted in non-synonymous amino acid changes than those in tissues of patients with OA.Mutations in mtDNA ... of mtDNA. They comprise a wide spectrum ofclinical symptoms that arise as a result of dysfunction of themitochondrial respiratory chain, mostly affecting tissues thatare highly dependent on...
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Báo cáo y học: "Genetic studies in osteoporosis - the end of the beginning" docx
... ZL, Qin YJ, He JW, Huang QR, Li M, Hu YQ, Liu YJ: Asso-ciation of polymorphisms in low-density lipoprotein receptor-related protein 5 gene with bone mineral density in postmenopausal Chinese ... Osteogenesis imperfecta type VII 605497LEPRE1 Prolyl 3-hydroxylase Osteogenesis imperfecta type VIII 610339PLOD2 Lysyl hydroxylase-2 Bruck syndrome (osteogenesis imperfecta with 601865joint contractures) ... hip.Meta-analysis may also produce findings that individualscreens have missed. Although in the past competitionbetween groups hindered data sharing for meta-analysis,there is a solid recognition...
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Báo cáo y học: "Rituximab treatment in rheumatoid arthritis: how does it work" pdf
... rituximab is associated with persistence of Blineage cells in specific body compartments. In a recent issue of Arthritis, Research & Therapy, Nakou andcolleagues [1] present an interesting study ... anti-citrullinated proteinantibodies), which can be found already in the preclinicalphase of the disease; the presence of lymphocyte aggre-gates containing B cells, which are often surrounded by largenumbers ... response mayprovide insight into the mechanism of action in RA. We andothers have previously shown that rituximab causes a rapiddecrease in numbers of B cells in the synovial tissue of RApatients...
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