Báo cáo khoa học: " Science review: Natriuretic peptides in critical illness" pps

... For example, forgetting to restart an infusion of heparin postoperatively is a lapse. Restarting the heparin infusion but entering an incorrect infusion rate despite knowing the correct rate ... involving continu- ously infused medications in a surgical intensive care unit. Crit Care Med 2004, 32:428-432. 80. Stambouly JJ, McLaughlin LL, Mandel FS, Boxer RA: Complica- tions of care in ......

Ngày tải lên: 25/10/2012, 10:35

... a preincubation for 20 min with 3 μg/ml lipofectin in serum-free Opti-MEM (Life Techn ologies, Inc.). After the beginning of the incubation (4 h), the medium con- taining ODN and lipofectin was ... Burlingame, CA). 3,3’-dia- minobenzidine tetrahydrochloride was used as a chro- mogen, and Mayer’s hematoxylin counterstaining was applied. Immunohistochemical staining of clusterin was defined ....

Ngày tải lên: 09/08/2014, 01:24

... ret- ropharyngeal nodes using MRI findings. After analyzing trade-off, we chose 15 cm 2 as the cut-off point in the validation cohort (additional file 1). Using this cut-off point, we further d ivided ... Johnson PJ: Final report of a randomized trial on altered-fractionated radiotherapy in nasopharyngeal carcinoma prematurely terminated by significant increase in neurologic complicatio...

Ngày tải lên: 09/08/2014, 09:20

... three distinct receptor tyrosine kinase inhibitors (RTKI), overlapping in inhibi- tion of PDGF signaling, attenuated radiation-induced pul- monary fibrogenesis in vivo [78]. The radiation-induced overexpression ... during imatinib treatment [36]. The clinical success of imatinib/gleevec, a triple tyrosine kinase inhibitor of c-kit, PDGF and c-Abl signaling, in chronic myeloid leukemia [...

Ngày tải lên: 09/08/2014, 10:21

... below). Cell-penetrating peptides working as antimicrobial peptides, and antimicrobial peptides working as cell-penetrating peptides A substantial number of mammalian cell-penetrating peptides, including TP-10, ... France Introduction There has been increasing interest in recent years in describing the complex, multifunctional role that anti- microbial peptides play in directl...

Ngày tải lên: 18/02/2014, 06:20

... present in the in ammatory in ltrate as well as in the epithelium migrating over the wound, but not at the wound edge. Interestingly, its highest level in the skin wounds is reached 48 h postinjury, ... defensins in psoriasis, ros- acea and atopic dermatitis, providing evidence that the concentration, processing and signaling of antimicro- bial peptides are critical parameters f...

Ngày tải lên: 18/02/2014, 06:20

... and leads to an increase in intracellular cAMP levels. The involvement of kinases, such as protein kinase C (PKC), phosphatidylinositide 3-kinase and mitogen- activated protein kinases has also ... from both C- and N-terminal sequences were synthesized and initially assayed in rat brain protein kinase C to identify which part of the entire protein maintained the in vitro effects describ...

Ngày tải lên: 07/03/2014, 05:20

... element containing amino acids 98–110 of the flavivirus E protein) may serve as an internal fusion peptide, as it is directly involved in interactions with target membranes during the initial stages ... induc- tion at the membrane interface in poly(Leu) stretches [11,12] and therefore play important structural roles in membrane-inserted peptide chains [13]. The direct involvement of fusi...

Ngày tải lên: 07/03/2014, 17:20

... containing peptides. In contrast with these ®ndings Etoh et al. [20] identi®ed a decapeptide with g rowth p romoting activity towards B. bi®dum , which contains neither cystine nor cysteine. Therefore, ... immunoglobulins act protectively by regulating the infants' i ntestinal m icro¯ora. A further precursor protein y ielding p eptidic b i®dus growth factors i s l actofer- rin. Intere...

Ngày tải lên: 23/03/2014, 21:21

... endotoxin-neutralizing molecules. We have determined 3D structures of antimicrobial peptides and designed peptides in complex with LPS, using NMR experiments, to gain insights into the peptide interactions ... determined the binding sites of LPS in the presence of polymyxin antibiotic peptides, using DPC-solublized isotope-labeled LPS [66]. Remaining challenges In order to form por...

Ngày tải lên: 29/03/2014, 22:21