... critically ill patients must be called into question.Competing interestsNone declared.References1. Cunha BA, Shea KW: Fever in the intensive care unit. Infect DisClin North Am 1996, 10:185-209.2. ... ofanimal models with fever and infection, call into question the routine practice of treating fever in critically ill patients.Keywords fever, heat shock proteins, intensive care unit, nuclear factor-κB, ... Suter PM, Ricou B: Is it worth treatingfever in intensive care unit patients? Preliminary results froma randomized trial of the effect of external cooling. Arch InternMed 2001, 161:121-123.9....