... use and the choice of one or another can be guided by the variety of parameters indicated, mainly according to the goal of the study and the importance of the species considered. Whatever the ... close to the coding sequences have been found, this has usually been done through the use of SNPs. The mapping of regions containing QTLs involves the genotyping...
Ngày tải lên: 09/08/2014, 18:21
... analysis revealed the presence of actin, the actin-related compo- nents a-actinin and gelsolin, tubulin including acety- lated a-tubulin, and the kinesin motor proteins KIF3A and KIF3B in these membranes ... with a-tubulin thereby forming a high-molecular weight complex [29]. This suggests stronger binding of TRPV1 to the plus end rather than the minus end of A B Fig...
Ngày tải lên: 30/03/2014, 10:20
Tài liệu Báo cáo khoa học: "What lies beneath: Semantic and syntactic analysis of manually reconstructed spontaneous speech" pdf
... concep- tion of transformation (Harris, 1957). In this view, the original verbatim string is the surface form of the sentence, and as in linguistic theory should be constrained in some manner ... modifying material. Reconstructive insertions 751 Proceedings of the 47th Annual Meeting of the ACL and the 4th IJCNLP of the AFNLP, pages 746–754, Suntec, Singapore...
Ngày tải lên: 20/02/2014, 07:20
Tài liệu Báo cáo khoa học: "Prosodic Aids to Syntactic and Semantic Analysis of Spoken English" ppt
... purpose of utteranc- es and their domain context, it is then possible to correct some of the insertion and mis-recognised word errors from the SR and determine the com- municative intent of the ... rules of the form A -> B C to the form A -> B Link C, and add con- straints to the rules application in terms of the value of the =breaking indi...
Ngày tải lên: 20/02/2014, 21:20
Báo cáo khoa học: MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells potx
... an Exportin-5-dependent mechanism, and further processed by the RNAse III enzyme Dicer, producing miRNA duplexes. One strand of the duplex is incorporated into the RNA-induced silencing complex, ... been used in the clinic for several decades, and its metabolic pathways and cyto- toxic modes of action through the inhibition of thymi- dylate synthase activity and inco...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Regulated expression by PPARa and unique localization of 17b-hydroxysteroid dehydrogenase type 11 protein in mouse intestine and liver pdf
... by PPARa and its ligand in the intestine than in the liver. 17b-HSD11 is distributed only in duodenum and jejunum To examine the distribution of the induced 17b- HSD11 along the gut, proteins from ... fractions of the intestinal mucosa and liver and antibodies to recombi- nant 17b-HSD11 is shown in Fig. 1B. The amounts of 17b-HSD11 protein were markedly ind...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Identification, subcellular localization and functional interactions of PilMNOWQ and PilA4 involved in transformation competency and pilus biogenesis in the thermophilic bacterium Thermus thermophilus HB27 ppt
... implicated in retraction of the PilA4-comprising DNA translocator transporting the DNA through the periplasmic space. Binding of the DNA to the DNA-binding protein ComEA on the surface of the inner ... mutations in either pilW or pilQ significantly affect the location of the other protein in the outer membrane. Furthermore, no PilA4 was present in the oute...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Refined solution structure and backbone dynamics of the archaeal MC1 protein ppt
... creating sufficient room for accepting DNA [20]. The tips of the arms are highly flexible, and once the DNA has moved inwards, the arms close and the tips of the arms wrap around the DNA. The amplitudes ... with the DNA-binding b-hairpin arms of HUs, which showed high mobility relative to the core (Fig. 2). The b-ribbon arms wrap around the minor groove of t...
Ngày tải lên: 22/03/2014, 17:20
Báo cáo khoa học: Glycogen synthase kinase 3b and b-catenin pathway is involved in toll-like receptor 4-mediated NADPH oxidase 1 expression in macrophages ppt
... on production of the pro -in ammatory cytokine inter- feron-b [26]. b-Catenin is one of the most important downstream molecules of the GSK3b pathway [27]. When b-catenin is released into the cytosol and ... need regulatory cofactors, including NoxO1, NoxA1 and Rac1 [5]. The most well-studied activation of Nox1 is that of angiotensin II mediating phospholi- pase C and...
Ngày tải lên: 22/03/2014, 21:21
Báo cáo khoa học: Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entry potx
... recep- tor binding [15]. Alteration in gD conformation then mobilizes gH and gL, a heterodimer, and gB to initiate the fusion process at the cell surface. Multiprotein complexes involving gD ⁄ gB and ... remains to be determined whether the inability to use 3-OS HS and additional differences in HS binding may have a role in the tissue tropism shown by the two HSV ser...
Ngày tải lên: 23/03/2014, 04:20