Báo cáo khoa học: " Effects of volume resuscitation on splanchnic perfusion in canine model of severe sepsis induced by live Escherichia coli infusio" pdf

... similar to those in controlanimals (Figs 1 and 2; Table 1).Regional effects of live Escherichia coli infusion and fluid replacement Live E. coli infusion resulted in marked reductions in mesenteric ... significant.ResultsSystemic effects of live Escherichia coli infusion and fluid replacementThe infusion of live E. coli promoted significant reductions in mean arterial pressure, cardiac index, DO2, and SVO2. In ... preparationA strain of Escherichia coli O55B, provided by the Adolfo LutzInstitute of Infectious Diseases, originating from the stool of apatient with gastrointestinal sepsis, was used in the...

Báo cáo khoa học: "Conformal radiotherapy for lung cancer: interobservers'''' variability in the definition of gross tumor volume between radiologists and radiotherapists" pot

... atelectasisthat constitutes the main cause of error in tumor volume delineation. We emphasize that in our study, we observedone case of tumor with mediastinal invasion, two withinvasion of the thoracic ... observed in the distribu-tion of data within the constructed confidence interval,and only one point fell outside the interval, indicatingthat the error among the measurements does not tend toincrease ... useful in defining the tar-get volume in the presence of atelectasis and in defininginvolved lymph nodes. [43]ConclusionRadiotheraphy plays an important role in the manage-ment of inoperable...

Tài liệu Báo cáo khoa học: Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase pdf

... The in vitro kinase reaction was initiated by the addition of kinase buffer containing 100 lm ATP, samples were incu-bated at 30 °C for 45 min, and reactions were terminated by the addition of ... andPtdIns3K ⁄ Akt pathway, as a consequence of inactiva-tion of EGFR [10–13]. The PtdIns3K ⁄ Akt pathway isdownregulated in response to geﬁtinib only in NSCLCcell lines that are growth-inhibited ... cells were incubated with the indicatedconcentrations of AG1478 for 48 h. The viability of cells was deter-mined by conducting WST-8 assays. The reading obtained foruntreated cells was considered...

Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

... glycine, l-alanine,l-proline, l-lysine, l-serine, b-alanine, taurine, sarcosine,dimethylglycine, glycine betaine, trimethylamine N-oxide,and cytidine 2¢-3¢ cyclic monophosphate were also obtainedfrom ... parameters of proteins in the presence andabsence of trimethylamine N-oxide. J Biol Chem 280,1035–1042.40 Monterroso B & Minton AP (2007) Effect of highconcentration of inert cosolutes on the ... of osmolytes on protein stability, folding and theactivity of proteins and enzymes, the relationshipbetween protein stabilization by osmolytes and its con-sequent effects on the activity of...

Báo cáo khoa học: Post-ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death ppt

... neurons in vitro [26]. Experimental research in the ﬁeld of ischemia was mainly prompted by observations indi-cating that CBs could attenuate glutamate -induced injury by inhibiting glutamate ... dif-ferential inhibition of glutamate or GABA in variousexperimental models of cerebral ischemia may be one of the principal reasons whereby activation of CBreceptors may lead to either neuroprotection ... detrimental effects of OGD in vitro by releasing glutamate in excess, indicating that the increase in 2-AG levelsthat was observed by these authors following OGDmay protect dopaminergic neurons through...

Báo cáo khoa học: "COMMON TOPICS AND COHERENT SITUATIONS: INTERPRETING ELLIPSIS IN THE CONTEXT OF DISCOURSE INFERENCE" ppt

... discourse model representations: in the case of parallel constructions, the source resided in the propo- sitional representation; in the case of non-parallel con- structions, the source had been integrated ... discourse. In Proceedings of the International Conference on Computational Linguistics (COLING-88), pages 573-577, Budapest, August. Mark Steedman. 1990. Gapping as constituent coordi- nation. Linguistics ... Understanding segments of utterances standing in a Common Topic relation requires the determination of points of commonality (parallelism) and departure (contrast) between sets of corresponding entities...

Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc

... Synoviolin, strongly suggesting that nicastrin is the substrate of Synoviolin. Interestingly, amyloid b-protein generation was increased by the overexpression of Synoviolin, although the nicastrin ... functional deletion of Synoviolin causes a change in the intracellular trafﬁcking of NCT.Effect of Synoviolin on the production of AbNCT is one of the essential cofactors of the c-secretasecomplex. ... b-protein genera-tion. It was found that the level of immature nicastrin was dramaticallyincreased in synoviolin-null cells as a result of the inhibition of degradation,but the accumulation of...

Báo cáo khoa học: "A Feedback-Augmented Method for Detecting Errors in the Writing of Learners of English" docx

... “mal-rule” scoring. In Proc. of 5th International Conference on User Modeling,pages 69–66.G. Minnen, F. Bond, and A. Copestake. 2000.Memory-based learning for article generation. In Proc. of CoNLL-2000 ... contains further useful in- formation. For example, we can obtain trainingdata consisting of instances of errors by compar-ing the feedback corpus with its original corpus.Also, comparing it ... articlesand the distinction between singular and plural.Finally, the tagged instances are stored in a ﬁlewith their surrounding words. Each line of it con-sists of one of the tagged instances and...

Báo cáo khoa học: Calcium-dependent protein–protein interactions induce changes in proximity relationships of Cys48 and Cys64 in chicken skeletal troponin I ppt

... Mapping of asecond actin-tropomyosin and a second troponin C binding sitewithin the C terminus of troponin I, and their importance in theCa2+-dependent regulation of muscle contraction. ... was to relate conformational changes in the N-terminal domain of chicken troponin I (TnI) toCa2+activation of the actin–myosin interaction. The twocysteine residues in this region (Cys48 and ... ﬂuorescence.Ca2+activation of striated muscle is mediated by thetroponin complex. Troponin is composed of three subunits:troponin C (TnC), a Ca2+binding subunit; troponin I(TnI), an inhibitory subunit and troponin...

Báo cáo khoa học: "What’s There to Talk About? A Multi-Modal Model of Referring Behavior in the Presence of Shared Visual Information" potx

... perform-ance of the visual-only model on the visual task conditions and the language-only model on the 12What’s There to Talk About? A Multi-Modal Model of Referring Behavior in the Presence of Shared ... tradeoffs be-tween relying on the linguistic context and the visual context. Our current instantiation of the integrated model could be enhanced by taking a more theoretical approach to integrating ... We conclude by presenting preliminary results and discussing future modeling plans. 2 Motivation There are several motivating factors for develop-ing a computational model of referring behavior...

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